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ProBiota HistaminX - 60 Vegetarian Capsules

Rated 4.8 out of 5
Based on 952 reviews

ProBiota HistaminX - 60 Vegetarian Capsules

Original price $32.95 - Original price $168.06
Original price


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$32.95 - $168.06
Current price


You save: $$$ (%)

Key Benefits and Actions

Key Benefits and Actions

  • Histamine-friendly probiotic formulated without strains known to produce high levels of histamine
  • Supports microbiome balance and a healthy gut response to ingested histamine
  • Supports the health of your immune system and skin

Who Needs ProBiota HistaminX

Does your histamine response get worse when using most probiotics? Do you have histamine concerns such as headaches, intestinal upset, skin issues, or heart palpitations? Are you looking to support your gut microbiome, but aren’t sure where to start?

ProBiota HistaminX is a unique probiotic supplement designed for those sensitive to histamine. It excludes strains known to produce high levels of histamine in the gut.

Most probiotic strains naturally produce histamine in the body. This can cause adverse reactions in people who struggle with excess histamine or histamine intolerance.

ProBiota HistaminX is a histamine-friendly probiotic. Unlike most probiotics, it has been meticulously formulated to exclude species of bacteria known to produce histamine. It is a great option for those struggling with histamine intolerance or looking for a probiotic that avoids producing excess histamine in the gut.

The targeted strains of bacteria are encased in a delayed-release (acid-resistant) capsule. This helps ensure the probiotics are delivered intact to your lower digestive tract, where they are needed.

If you have histamine intolerance, it may seem like the only way to avoid unpleasant side effects is to eliminate high-histamine foods altogether. However, such a restricted diet can end up depriving your body of certain nutrients. It can also make enjoying your meals an unnecessary challenge!

Your gut health is a key factor in maintaining healthy histamine levels throughout your body. With nearly 400 5-star reviews, ProBiota HistaminX is a best-seller for good reason. Thousands of people worldwide use it every day to support healthy gut bacteria and histamine metabolism. Whether or not you struggle with histamine, ProBiota HistaminX was designed to support your daily gut health in only one capsule per day.

** ProBiota HistaminX has met standards for ingredient and product quality for Probiotics in independent testing. More information at

Customer Review

This really seems to help with my histamine intolerance!

I'm several months into a histamine lowering regimen that includes these probiotics and a very low histamine diet. These have really helped to 'empty the bucket' of histamines I've been dealing with and my symptoms are much more manageable. Thank you! ~Sierra

Key Ingredients In ProBiota HistaminX

  • Histamine-friendly probiotics: Support the body’s response to food-derived histamine, specifically excluding strains known to produce histamine.
  • Acid-resistant capsules: Protect probiotics from stomach acid to help deliver them intact to the gut.
  • Inulin-Free: Does not contain inulin for those who are sensitive to prebiotics and carbohydrates.

Why ProBiota HistaminX Works

Histamine is metabolized in your body via your DAO (diamine oxidase) enzymes. Due to genetic variations, some individuals have slower DAO enzymes. Your DAO enzymes can also become stressed from your environment or lifestyle. This can slow down histamine metabolism, leading to high histamine levels. DAO enzymes can be further slowed by leaky gut, alcohol, and certain drugs. Slow enzyme activity combined with high-histamine foods can cause high histamine levels in your body. This, in turn, can lead to increased levels of inflammation and histamine intolerance in a vicious cycle.

Intestinal microbes assist us in digesting foods. In the process, they may produce byproducts that either help or harm us. Some specific bugs like Salmonella typhi have long been known to irritate the intestinal tract and increase the release of histamine in immune cells. Some organisms used as probiotics (like Lactobacillus casei and Lactobacillus d. bulgaricus) may also contribute to a build up of gut histamine levels. In someone with histamine intolerance, this may lead to a rise in histamine associated complications.

A healthy microbiome is essential to support your body’s response to histamine. Gut health can also alleviate potential stress from slowed DAO enzyme activity. The probiotic strains found in ProBiota HistaminX help to lessen your DAO enzyme’s workload by excluding species known to produce histamine. This unique probiotic also supports a healthy response to histamine from food and a normal inflammatory response in the gut. By lessening your DAO enzyme’s workload, you can support the efficiency of your histamine pathway.

ProBiota HistaminX
Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 60

Probiotic Blend 81.8 mg **
Bifidobacterium infantis
Bifidobacterium bifidum
Lactobacillus salivarius
Bifidobacterium longum
Lactobacillus plantarum
Bifidobacterium lactis
Bifidobacterium breve
 Total Cultures 10 Billion CFU
**Daily Value (DV) not established.

Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose, water, gellan gum), L-leucine, and silica.

  • Suitable For: Vegetarians and Vegans
  • Age Suitability: Adults
  • Delivery Method: Capsules
  • How To Store: Keep tightly closed to maintain potency. Do not freeze. Keep out of reach of children.

    This product does not require an ice pack during shipping, click here to learn more.

Free Of: Eggs, Fish, Gluten, GMO, Milk, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use ProBiota HistaminX

Suggested Use

Take 1 capsule daily with or without food or as directed by your healthcare professional.


Children and pregnant or lactating women should consult their healthcare professional prior to use. Keep out of reach of children.

Constipation or shifts in bowel movements may occur when first beginning a probiotic regimen. If this happens, stop taking ProBiota HistaminX until normal bowel movement occurs. If bowel movements do not return to normal, stop use and consult a healthcare professional.

ProBiota HistaminX is NOT EFFECTIVE for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease. DAO is not absorbed and does not have systemic activity. ProBiota HistaminX does not manage or address antibody-related or IgE-related food allergies.

How to Enhance ProBiota HistaminX


Consider Pulsing

Dr. Ben Lynch recommends using certain dietary supplements based on your need for them. Start with a partial serving and increase slowly over time to the full serving, only if needed. When you start feeling good, consider reducing the serving size, skipping days, or pausing supplementation. Then take again when you feel you need it (stressful day, traveling, chemical exposure, etc.), hence "pulsing." Work with your qualified healthcare practitioner to determine what's best for you.


Pairs Well With

Optimal Electrolyte, to support optimal hydration. Optimal Liposomal Vitamin C Plus, to support normal DAO production and healthy inflammatory responses. Histamine Block, for more immediate histamine support. Intended to be taken with high-histamine meals, Histamine Block provides DAO (diamine oxidase) to support the metabolism of histamine from food.†‡


Clean Your Genes

After years of suffering from unexplainable health issues, Dr. Ben Lynch, ND discovered the root cause - "dirty" genes. In his best-selling book, Dirty Genes, Dr. Ben Lynch describes the steps you can take to promote optimal epigenetic health. Ready to get started? Click here to take the Dirty Genes Quiz to find which of your genes are dirty!

Why Choose Seeking Health

Here at Seeking Health, we are committed to providing you the best in bioavailable supplements, methylation support, prenatal vitamins, genetic analysis tools, and more.

We strive to go above and beyond the average supplement company, which is why we allocate significant resources to testing all of our supplements for purity, potency, and label claims.

  • Third-party tested for heavy
    metals, microbials, and potency
  • Scientifically formulated by Dr. Ben Lynch, ND
  • Manufactured in the USA from globally
    sourced ingredients
  • Nutrients in their bioavailable
    forms for optimal absorption
  • cGMP facility registered by NSF International
Purity & Potency Tested & Assured
Scientifically Formulated by Dr. Ben Lynch
Manufactured in the USA from globally sourced ingredients third-party independently tested
Bioavailable Nutrients

FAQs for ProBiota HistaminX

What is the purpose of each ingredient in ProBiota HistaminX?

Ingredients Purpose
Bifidobacterium bifidum, bifidobacterium longum, bifidobacterium lactis, bifidobacterium breve, bifidobacterium infantis, lactobacillus salivarius, lactobacillus plantarum Support healthy microbiome bacteria

What strains are contained in ProBiota HistaminX, and in what amounts?

The amounts of each strain and strain numbers are proprietary. ProBiota HistaminX is 100% strain-specific to maintain consistency from lot to lot.

You can see the species that are included in ProBiota HistaminX here: Probiotic Supplement Comparison Chart.

Which histamine product is right for me?

Click here to view our Histamine Supplement Comparison Chart.

We wrote an article sharing our Top 5 Histamine Intolerance Products.

If you have a question that's not addressed
here, see all frequently asked questions.


Do you have Questions
for this Product?


What our customers say

Real reviews from real customers.

average rating 4.8 out of 5
Based on 952 reviews
  • 5 Stars
    849 Reviews
  • 4 Stars
    74 Reviews
  • 3 Stars
    9 Reviews
  • 2 Stars
    8 Reviews
  • 1 Star
    12 Reviews
97% of reviewers would recommend this product to a friend
Customer photos and videos
952 Reviews
Reviewed by Samifer S., from United States
Verified Buyer
We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback!
I understand
Rated 3 out of 5
Review posted

Have a sensitivity to this probiotic

Our Integrative Med Dr recommended this for my daughter and me for high histamine issues. We have really wanted this product to work, understanding we need to give it time to do so, as well as the pulse method. However, each time we try this, we get itchy rashes on our skin and flushing. We are familiar with high histamine reactions, however this probiotic we really struggle with - even taking a 1/3 of a capsule. We keep trying it in all different methods, and after different treatments - but we can't seem to adjust to be able to get this particular probiotic to work for us. It does constipate me, - and Dr Lynch does a great job at educating on his products! Love this about Seeking Health and will continue to try more of their products on top of the many other fabulous products they offer!

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We apologize you are experiencing these side effects with this product. Please reach out to Customer Service to discuss a return/refund (800) 547-9812 or email

Reviewed by Aleksandra B., from United States
Verified Buyer
I recommend this product
We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback!
I understand
Rated 5 out of 5
Review posted

Improving my health

I really like these capsules. I use them to make my own yogurt and I also take them every morning. I used to have really strong reactions to different foods but have been able to diversify my diet and I also feel like the foods that bother me don't bother me as much. Will keep buying these!

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Reviewed by Rod S., from Canada
Verified Buyer
I recommend this product
We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback!
I understand
Rated 5 out of 5
Review posted

Second purchase

I purchased this product earlier this year when I finally learned histamine was elevated in my gut but had crossed epithelial wall in gut into bloodstream and was now triggering many more symptoms other than gut (bloating, borborygmi, flatulence). Unfortunately then, I struggled to understand ALL the possible factors contributing to the variance and how much. Initially, I thought supplementing with DAO would solve however, that's not the case - at least with me. I have since learned not being breastfed (Bifidobacterium species increases 100 fold during pregnancy) may have significantly increased my risk for elevated histamine I now experience as an adult since strains from Bifidobacterium may significantly degrade histamine in infants and in turn colonize gut for possible lifetime barrier to elevated histamine. But other factors such as alcohol, foods and stress that trigger mast cells, limited DAO activity ALL may play a role in my current battle to lower histamine. Thus, I was not disciplined taking this product and in fact tossed unused bottle. Thus, I have reordered because a probiotic (histamine degrading) along with controlling the other factors I just listed are important to possibly restoring normal histamine - at least in myself. I have come a long way in 6 months so I will check back with the community to update my rating but for now I'll give it 5 stars based on the fact that the product seems to have key histamine degrading bacteria. Cheers, RS

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These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.