Methylate Chewable - 60 Tablets

Rated 4.4 out of 5
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Key Benefits and Actions*

Methylate Chewable by Seeking Health provides a lower dose of methylation support for those who are sensitive to the higher doses found in most methyl support supplements. We’ve included active forms of folate, vitamin B12 and nine other targeted nutrients to help support and optimize healthy methylation processes throughout your body.*


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Methylation is an extremely important biochemical reaction that’s happening every second in every cell of your body. On the cellular level, methylation is the process of transferring a methyl group (CH3) to a molecule, which activates the molecule so it can be used by the body.


For example, attaching a methyl group to folate transforms it into the active form known as 5-MTHF (l-methylfolate), which is the predominant form of folate found in the body and the only form that can cross the blood-brain-barrier. Likewise, adding a methyl group to homocysteine (a marker of inflammation and cardiovascular disease) converts it back into methionine, a harmless amino acid. The addition and removal of methyl groups to and from DNA are responsible for turning genes on and off.


People with the MTHFR gene mutation (especially the C677T variety) can have significant reductions in methylation (even if they take plenty of folate) and may benefit from supplementing with activated forms of folate, B12 and other methyl-supportive nutrients.* When you have two copies of the MTHFR gene (homozygous) it becomes even more important to provide methylation support for your body, however, taking high doses can lead to overmethylation. Common symptoms of too much methylation support include headaches, irritability, insomnia, runny nose, body pain, and itchy skin.


Methylate Chewable was created by Dr. Ben Lynch to address the need for an easy-to-take vitamin that supports methylation quickly, comprehensively, and gently. The lower amounts per serving allow you to optimize rather than overwhelm your methylation cycle. By supporting methylation gently, common unpleasant side effects of taking methylation support may be lessened or prevented completely.*


The targeted ingredients found in Methylate Chewable are designed to provide the following benefits and actions:*

  • Riboflavin is the primary vitamin needed to support the MTHFR enzyme. Riboflavin also helps in the recycling of glutathione (the body’s master antioxidant) along with supporting the metabolism of serotonin, epinephrine, norepinephrine, and histamine

  • Niacin helps to support histamine metabolism while providing a calming effect

  • Vitamin B6 is used in the conversion of harmful homocysteine into beneficial glutathione. Vitamin B6 also supports the production of GABA, a calming neurotransmitter

  • Folate is included in two forms: 80% as L-5-MTHF (l-methylfolate) and 20% as folinic acid. L-5-MTHF is the active methylated form of folate needed to produce the body's main methyl donor, SAMe. Folinic acid is involved in the production of energy and BH4 (an important cofactor in the body)

  • Vitamin B12 is included in three different forms: methylcobalamin to support methylation, hydroxocobalamin to balance reactive forms of nitric oxide and hydrogen sulfide, and adenosylcobalamin to support mitochondrial health and energy production

  • Choline and betaine (TMG) support the recycling of homocysteine back to methionine via the BHMT enzyme. Choline also supports the synthesis of phosphatidylcholine, which uses a large majority of the body’s methylation reactions to produce

  • Magnesium is required for the production of the body's main methyl donor, SAMe. Magnesium also supports the COMT enzyme, which can be a common culprit of methylation side effects

  • Zinc is an important cofactor for the MTR and BHMT enzymes, which helps them bind to homocysteine. Zinc also supports the reduction of excitatory NMDA activity

  • Molybdenum helps support the metabolism of sulfites, which is important if one consumes too much methylation support

  • PQQ helps support the reduction of oxidative stress, which when present, can slow the methylation cycle. PQQ is also protective to BH4, which helps support the production of neurotransmitters and the healthy form of nitric oxide

Suitable for Vegans and Vegetarians

Free of:

Milk, Egg, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, Artificial Colors, Artificial Flavors

Suggested Use

Chew 1 tablet with or without food. Tablets may be cut into halves or quarters if a lesser dose is desired and taken throughout the day. Do not take within 5 hours of bedtime as it may interfere with sleep. Use as directed by your healthcare professional.

Warnings

Children and pregnant or lactating women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged.

Looking for complimentary support?

Additional supplements that complement Methylate Chewable are:

Serving Size: 1 Tablet
Servings Per Container: 60

AMT %DV
Calories 5
Total Carbohydrate 1 g <1%
Riboflavin (as riboflavin and riboflavin 5'-phosphate sodium) 2.5 mg 192%
Niacin 2.5 mg 16%
Vitamin B6 (as pyridoxal 5'-phosphate and pyridoxine HCl) 2.5 mg 147%
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt and calcium folinate] 170 mcg DFE (100 mcg) 43%
Vitamin B12 (as methylcobalamin, hydroxocobalamin, and adenosylcobalamin) 38 mcg 1,583%
Choline (as choline bitartrate) 25 mg 5%
Magnesium (as magnesium citrate) 25 mg 6%
Zinc (as Zinc Bisglycinate Chelate§) 1.25 mg 11%
Molybdenum (as Molybdenum Glycinate Chelate§) 12 mcg 27%
Betaine Anhydrous (trimethylglycine) 62.5 mg **
Pyrroloquinoline Quinone Disodium Salt 1.5 mg **
Percent Daily Values are based on a 2,000 calorie diet.
**Daily Value (DV) not established.

Other Ingredients: Xylitol, natural flavors, ascorbyl palmitate, silica, stevia leaf extract, sea salt, monk fruit extract, citric acid, and malic acid.

Learning Center Find product FAQ and more! Click here.
Cost Per Serving $0.63
Delivery Method Chewable Tablet
Storage Keep tightly closed in a cool, dry place out of reach by children.
Age Suitability Adult
Manufactured In USA
Case Quantity 24
Dimensions (in.) Length: 2.5 / Width: 2.5 / Height: 5.25
Weight (lb.) 0.4000
SKU METHYL-60-TAB
Barcode 810007520698
Return Policy Learn more about our Return Policy.
average rating 4.4 out of 5
Based on 47 reviews
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81% of reviewers would recommend this product to a friend
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47 Reviews
Reviewed by Kathy G., from United States
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Great Tasting

I am sensitive to mentholated folate and B-12. These wafers are great as you can break off a smaller amount to take if you need to.

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Reviewed by Teresa Wemheuer T., from United States
Verified Reviewer
I recommend this product
Rated 5 out of 5
Review posted

Good stuff

Just started using but it is working great

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Reviewed by Kellie G., from United States
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Methylated chewables

I love them it’s like taking a shot of clarity. I seem to be able to focus better. I can’t imagine not taking one daily now.

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Reviewed by Heather H.
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Methylation is key

Everything you could want wrapped into one great tasting chewable!!

Highly recommend this to anyone especially those with absorption problems.

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Reviewed by Megan, from United States
Verified Reviewer
I recommend this product
Rated 5 out of 5
Review posted

My kids ask for these!

The cherry flavor of these is a winner for my kids. They ask me to buy more when they know we're out.

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