Your DAO gene makes an enzyme known as diamine oxidase (also called DAO). DAO enzymes are necessary for processing histamine, a chemical in your body that gets released in response to some foods or inflammatory situations. Gut bacteria can also produce histamine.
While you need some histamine, if your body does not have enough DAO, your histamine reactions to foods and common environmental exposures will seem more pronounced. You might feel itchy, sneezy, get rashes, hives, or experience bloating. Histamine intolerance can be common but is not a food allergy. It simply means that your body needs more DAO enzyme. (Food allergies are different, serious reactions. Supplementing with DAO does not help these.)
Nutrients that support healthy DAO activity include vitamin C, quercetin, vitamin B6, magnesium, and DAO enzyme supplements.
To support healthy DAO levels and healthy histamine levels, you can take a DAO supplement and other supportive cofactors. Histamine Digest and Histamine Block Plus are Seeking Health’s supplements that promote a healthy response to ingested histamine. ProBiota HistaminX is a gut health supplement to help promote a healthy digestive tract and intestine response to histamine.
Get started with DAO gene supplements today. Use this comparison chart to decide which histamine products are right for you.