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Seeking Health will be closed on Monday the 29th in observance for Memorial Day.

Serotonin Nutrients - 60 Capsules

Rated 4.3 out of 5 stars
31 Reviews

Serotonin Nutrients - 60 Capsules

Original price $39.95 - Original price $203.76
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  • Supports healthy feelings of patience and happiness
  • Supports a healthy response to carb cravings
  • Supports a healthy sleep duration and quality of sleep
This formula contains niacin. When taken on an empty stomach, a healthy response to niacin supplementation may include mild blushing, warming, or tingling of the skin. See below for more details.

Who Needs Serotonin Nutrients

Do you regularly experience stressful moments, struggle with recurring infections or experience unhealthy levels of inflammation? If so, you may not be producing healthy levels of serotonin. This is because in times of stress, infections or inflammation, your body uses tryptophan to support a healthy immune response.

Modern living affects our mood, sleep, cravings and digestion. Research is indicating that common lifestyle factors are decreasing levels of serotonin.

Why are serotonin levels important? Serotonin is the neurotransmitter that:

  • Supports healthy levels of inflammation
  • Supports normal feelings of calm and happiness
  • Supports healthy sleep duration as serotonin converts to melatonin
  • Supports healthy libido vs excessive desire
  • Supports healthy duration of male orgasm vs premature
  • Supports relaxation vs being obsessive or compulsive about things
  • Is found in your gut in high amounts where it supports healthy appetite
  • Supports healthy movement of your stool through your digestive tract

If you can relate to one or more of the following statements, then Serotonin Nutrients may be helpful for you in supporting healthy serotonin levels:

If you are lacking serotonin, you may crave foods and behaviors that increase serotonin levels. This leads to an increase in the consumption of carbs, sweets or other addictive foods and behaviors. By supporting balanced serotonin levels, Serotonin Nutrients may support healthy food and behavior choices.

Maybe you have tried to take 5-HTP to support a healthy mood and it hasn’t worked. Why? It may be that making serotonin is not enough for you. Your body needs to get serotonin where it needs to go and that is delivered, and bound, to the serotonin receptors.

If you have been searching for a comprehensive serotonin support supplement, you have found what you are looking for with Serotonin Nutrients.

Customer Review


This supplement has been a game changer for me! Whenever I am feeling a little down or not upbeat I take one of these capsules and feel rejuvenated. This is great for when you need that extra boost on those grey days. Really happy with this formula. Seeking Health, great job! ~Jason P.

Key Ingredients In Serotonin Nutrients

  • HTPurityTM: Patented 5-HTP, the direct precursor for Serotonin
  • Safr’inside (R ) Saffron extract: Supports healthy levels of serotonin
  • Vitamin B6 (Pyridoxyl-5-Phosphate): Cofactor for DDC enzyme that makes serotonin
  • Inositol: Supports healthy serotonin receptor signaling

Why Serotonin Nutrients Works

Utilizing necessary nutrient cofactors, saffron extract, curcumin, and inositol, this complex formula is a unique serotonin support supplement.

Serotonin Nutrients works by providing a 4-prong approach to supporting serotonin levels:

  1. Conservation
  2. Synthesis
  3. Enhancement
  4. Persistence

The targeted ingredients of Serotonin Nutrients have specific functions:

  • Niacin and Curcugen®, a clinically researched curcumin extract, both work to conserve tryptophan, and thus, serotonin levels.
  • The essential nutrients (5-HTP and vitamin B6) are used by the AADC enzyme to synthesize serotonin.
  • Inositol supports healthy serotonin receptor signaling, and thus, enhancement of serotonin.
  • Safr’InsideTM, a patented saffron extract that supports the maintenance of healthy serotonin levels by slowing the reuptake of serotonin from the synapse.

To make serotonin, your body needs the AADC enzyme to function. This enzyme requires 5-HTP and vitamin B6 as P-5-P. If these nutrients are unavailable, your AADC cannot function and thus, low serotonin is the consequence.

Let’s say you have sufficient 5-HTP and vitamin B6 as P-5-P. You still may have low serotonin troubles.

Here’s why. Once serotonin is made, it is passed into the synapse where it travels and binds to serotonin receptors. Once serotonin is bound to the receptor, only then can you experience the effects of serotonin. Of course, a couple things may prevent serotonin from binding to the receptor.

  1. Serotonin can be broken down by your MAOA and MAOB enzymes. This is more common in people that have “fast” MAOA and MAOB activity.
  2. Serotonin can be removed out of the synapse by the serotonin transporter.

Neither of these options are good if you are experiencing symptoms of low serotonin. Remember, in order to experience the effects of serotonin, it must bind to the serotonin receptor. Receptor binding cannot occur if serotonin is broken down or removed by the serotonin transporter. Your body has gone to all the work of making serotonin for you, yet you receive none of the benefits.

This is where Safr’InsideTM comes to the rescue. For centuries, cultures around the globe have found success in supporting a healthy mood with the herb saffron. Research is now explaining why. The compounds found in the patented Safr’InsideTM ingredient used in Serotonin Nutrients appear to slow down important enzymes. Both of the MAOA and MAOB enzymes are slowed down by saffron which helps keep serotonin in the synapse longer. Saffron also slows the reuptake of serotonin by inhibiting the activity of the serotonin SLC6A4 transporter. This transporter is responsible for removing more serotonin from the synapse. If serotonin is removed from the synapse, it’s not available to bind to serotonin receptors. Thus, this saffron derived ingredient supports serotonin traveling, and binding to, the serotonin receptors.

Once bound to the receptors, serotonin initiates a signaling process that relies on inositol to carry out its function. Serotonin Nutrients includes this important ingredient.

Serotonin Nutrients
Supplement Facts

Serving Size: 1 capsule
Servings Per Container: 60

Supplement Facts

Vitamin B6 (as pyridoxal-5-phosphate) 10 mg 588%
Niacin (as nicotinic acid) 25 mg NE 156%
5-hydroxytryptophan (5-HTP) (from Griffonia simplicofolia)(seed) 50 mg **
Inositol 350 mg **
Saffron Extract (Crocus Sativus L)(stigma)(Safr'Inside™) 30 mg **
Tumeric Extract (Curcuma longa)(rhizome)(Curcugen®) 100 mg **
**Daily Value (DV) not established.

Other Ingredients: Vegetarian capsule (hypromellose and water), ascorbyl palmitate, L-leucine, and silica.

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Capsules
  • How To Store: Keep closed in a cool, dry place out of reach of children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use Serotonin Nutrients

Suggested Use

Take 1 capsule with food any time of day, or use as directed by your healthcare professional. Take before bed to support healthy sleep duration. Capsule may be opened and sprinkled on a bite of food if lower serving is desired.


Do not use if you are using a Selective Serotonin Reuptake Inhibitor (SSRI) or if you are pregnant. Children, lactating women, those taking psychiatric or neurological medications should consult their healthcare provider prior to use for specific healthcare advice. Do not use if tamper seal is damaged. This supplement may not be suitable for individuals with a slow MAOA, MAOB, or COMT gene.

Niacin Flushing: This formula contains niacin. When taken on an empty stomach, a healthy response to niacin supplementation may include mild blushing, warming, or tingling of the skin. This can appear on the ears, face, arms, torso, or occasionally on the legs. Commonly referred to as a "niacin flush", this harmless response normally dissipates within an hour. It is related to niacin's role in vasodilation (widening of blood vessels). Vasodilation leads to better circulation, capillary flushing, and increased blood flow to the surface of the skin. To minimize or prevent flushing, consider taking this supplement with food or in divided doses.

How to Enhance Serotonin Nutrients


Consider Pulsing

Dr. Ben Lynch recommends using certain dietary supplements based on your need for them. Start with a partial serving and increase slowly over time to the full serving, only if needed. When you start feeling good, consider reducing the serving size, skipping days, or pausing supplementation. Then take again when you feel you need it (stressful day, traveling, chemical exposure, etc.), hence "pulsing." Work with your qualified healthcare practitioner to determine what's best for you.


Pairs Well With

Vitamin D3 plays a key role in supporting serotonin synthesis by inducing the activity of the tryptophan hydroxylase enzyme. Lithium Orotate supports normal feelings of happiness and calm. Adrenal Nutrients support a healthy response to stress. Normalizing stress response may assist in tryptophan being available for serotonin production


Clean Your Genes

After years of suffering from unexplainable health issues, Dr. Ben Lynch, ND discovered the root cause - "dirty" genes. In his best-selling book, Dirty Genes, Dr. Ben Lynch describes the steps you can take to promote optimal epigenetic health. Ready to get started? Click here to take the Dirty Genes Quiz to find which of your genes are dirty!

Why Choose Seeking Health

Here at Seeking Health, we are committed to providing you the best in bioavailable supplements, methylation support, prenatal vitamins, genetic analysis tools, and more.

We strive to go above and beyond the average supplement company, which is why we allocate significant resources to testing all of our supplements for purity, potency, and label claims.

  • Third-party tested for heavy
    metals, microbials, and potency
  • Scientifically formulated by Dr. Ben Lynch, ND
  • Manufactured in the USA from globally
    sourced ingredients
  • Nutrients in their bioavailable
    forms for optimal absorption
  • cGMP facility registered by NSF International
Purity & Potency Tested & Assured
Scientifically Formulated by Dr. Ben Lynch
Manufactured in the USA from globally sourced ingredients third-party independently tested
Bioavailable Nutrients

FAQs for Serotonin Nutrients

What is the purpose of each ingredient in Serotonin Nutrients?

Ingredients Purpose
Vitamin B6 (P-5-P) Supports normal serotonin production (cofactor for DDC/AADC enzyme which makes serotonin)
Niacin Slows IDO1 which preserves tryptophan for serotonin synthesis
HTPurityTM 5-Hydroxytryptophan (5-HTP) Supports normal serotonin production (substrate for DDC/AADC enzyme which makes serotonin)
Inositol Supports normal serotonin utilization (supports serotonin receptor signaling)
Safr’Inside Saffron Extract Supports normal serotonin utilization (shows inhibition activity of MAOA and MAOB that degrade serotonin, and the SLC6A4 enzyme that reuptakes serotonin)
Curcugen® Turmeric Extract Supports a healthy inflammatory response, slows IDO1 which preserves tryptophan for serotonin synthesis - and slows SULT1A3 which preserves active serotonin

Who is Serotonin Nutrients intended for?

Serotonin Nutrients is intended for people who want to support a healthy mood, a healthy response to food or alcohol cravings, and to support normal serotonin production. Dr. Lynch recommends this product to those who have a fast MAOA or MAOB gene, according to his book Dirty Genes.

How to use Serotonin Nutrients?

Take 1 capsule with food any time of day, or use as directed by your healthcare professional. Take before bed to support healthy sleep duration. Capsule may be opened and sprinkled on a bite of food if lower serving is desired.

If you have a question that's not addressed
here, see all frequently asked questions.


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What our customers say

Real reviews from real customers.

Rated 4.3 out of 5 stars
Based on 31 reviews
Total 5 star reviews: 22 Total 4 star reviews: 4 Total 3 star reviews: 1 Total 2 star reviews: 1 Total 1 star reviews: 3
84%would recommend this product
31 reviews
  • KM Profile picture for Kat M.
    Kat M.
    Verified Buyer
    I do not recommend this product
    Rated 1 out of 5 stars
    2 days ago
    Please bring 5HTP back

    Unfortunately, the product did not work for me at all and actually had a very negative mood consequence (note - I was taking 5HTP prior, so this effectively reduced that dose).

    Please bring back the 5HTP.

    SH Profile picture for Seeking Health
    Seeking Health
    11 seconds ago

    Hello Kat,

    Thank you for reaching out to us! I have added your feedback (to bring back the 5HTP) to our customer feedback file that is reviewed monthly!

  • SP
    Sue P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6 days ago

    I'm just trying these. I think I may need them more during the gray season. It's bright and sunny finally so I haven't had a chance to give them a good trial

    I trust the company. Customer service is great. Shipping is very fast. You can fin out so much by Dr Ben on social media or his u tube

  • JM Profile picture for Jill M.
    Jill M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Most helpful!

    Serotonin Nutrients has helped me experience the deepest sleep in a long while! A great product for me taking with a large lunchtime meal several hours before sleep. Very Happy, will reorder! Thank you

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These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.