Adenosylcobalamin is a non-methylated, active form of vitamin B12. It is present in the mitochondria of cells in large quantities. Here, it supports cellular energy production (ATP).†
Adenosylcobalamin is used as a coenzyme for the Methylmalonyl CoA Mutase (MCM) enzyme. This important enzyme facilitates the creation of energy from cholesterol, branched-chain amino acids, odd chain fatty acids, and propionate (from gut bacteria). It converts these substances into succinyl CoA, which can enter the Krebs cycle to create ATP (energy). By supplementing with adenosylcobalamin, you provide your body with the compounds necessary to support healthy energy production.†
This methyl-free B12 is readily converted into cobalamin that enters the cell’s cobalamin pool. When needed, cobalamin is pulled from this pool for your body to use in various processes, including methylation. Cobalamin plays essential roles in the methylation cycle to support homocysteine breakdown to methionine.†
Homocysteine levels may increase with poor homocysteine metabolism. Cardiovascular and general wellness are dependent upon maintaining healthy homocysteine levels.†
Your body needs vitamin B12 and methylfolate (L-5-MTHF) to metabolize homocysteine into methionine via the MTR enzyme. From methionine, SAMe is created, your body’s main methyl donor. SAMe donates methyl groups to support your body’s methylation processes, including DNA expression.†
Without adequate B12, your body cannot effectively utilize methylfolate through the MTR enzyme. By consuming Adeno B12, you are giving your body indirect methylation support without the side effects some people experience from methyl groups.†
Most B12 dietary supplements contain the active ingredient cyanocobalamin. Before it can be used, your liver must first convert cyanocobalamin into an active form and discard the cyanide. If a person already has exposure to cyanide from cigarette smoke, fire smoke, or other sources, an alternative form of B12 such as adenosylcobalamin may be a healthier option.†
Here at Seeking Health, you’ll never find the cyanide-containing form, cyanocobalamin. Instead, you’ll only find bioavailable forms of vitamin B12 that your body can quickly recognize and utilize.†
Because B12 needs folate to support proper methylation, be sure to pair Adeno B12 with a bioactive form of folate, such as methyl-free Folinic Acid.†
It has never been easier (or more delicious!) to get your daily B12. If you’re looking to support healthy energy and methylation (without the side effects of methyl groups), Adeno B12 is the perfect formula for you!†