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ProBiota HistaminX Powder

SALE $69.95
  • Histamine-friendly probiotic formulated without strains known to produce high levels of histamine
  • Supports microbiome balance and a healthy gut response to ingested histamine
  • Supports the health of your immune system and skin

Who Needs ProBiota HistaminX Powder

Does your histamine response get worse when using most probiotics? Do you have histamine issues such as headaches, food intolerance, hives, or heart palpitations? Are you looking to support your gut microbiome, but aren’t sure where to start?

ProBiota HistaminX Powder is a unique probiotic supplement designed for those sensitive to histamine. It excludes strains known to produce high levels of histamine in the gut.†‡

This convenient powder version of our best-selling probiotic is ideal for adding to food or smoothies. In addition, it’s an excellent option for those needing to adjust their serving size more effectively than a capsule delivery.

Most probiotic strains naturally produce histamine in the body. This can cause adverse reactions in people who struggle with excess histamine or histamine intolerance.

ProBiota HistaminX Powder is a histamine-friendly probiotic. Unlike most probiotics, it is meticulously formulated to exclude the different strains of bacteria known to produce histamine. It’s a great option for those struggling with histamine intolerance or looking for a probiotic that avoids excess histamine production in the gut.†‡

If you have histamine intolerance, it may seem like the only way to avoid unpleasant side effects is to eliminate high-histamine foods altogether. However, a low-histamine diet can be restrictive and end up depriving your body of certain nutrients. It can also make enjoying your meals an unnecessary challenge!

Your gut health is a key factor in maintaining healthy histamine levels throughout your body. With nearly 400 5-star reviews, our ProBiota HistaminX product line is best-selling for good reasons. Thousands of people worldwide use it every day to support healthy gut bacteria and histamine metabolism. Whether or not you struggle with histamine, ProBiota HistaminX Powder will support your daily gut health in an easy powder delivery.

Because there is no acid-resistant component to this powder form, you will want to consume it with food to prevent stomach acid degradation of the microbes. Simply add to smoothies or sprinkle on food for a healthy histamine recipe!

Customer Review

These are so much better than the capsules!

Wow! There is no going back. I am EXTREMELY sensitive to probiotics and specific strains will trigger a histamin reaction. That is not the case with the powder. I love that my body no longer has to break down capsules and there is now a better, more potent product in this powder form! Thanks Seeking Health! No more headaches or reactions like I do with regular probiotic formulas. ~Ermorriak

Key Ingredients In ProBiota HistaminX Powder

  • Histamine-friendly probiotics: Support the body’s response to food-derived histamine, specifically excluding strains known to produce histamine.
  • Inulin-Free: Does not contain inulin for those who are sensitive to prebiotics and carbohydrates.

Why ProBiota HistaminX Powder Works

Histamine is metabolized in your body via your DAO (diamine oxidase) enzymes. Due to genetic variations, some individuals have slower DAO enzyme activity. Your DAO enzymes can also become stressed from your environment or lifestyle. This can slow down histamine metabolism, leading to high histamine levels. DAO enzymes can be further slowed by leaky gut permeability, alcohol, and certain drugs. Slow enzyme activity combined with high-histamine foods can cause high histamine levels in your body. This, in turn, can lead to increased levels of inflammation and histamine intolerance in a vicious cycle.

Intestinal microbes assist us in digesting foods. In the process, they may produce byproducts that either help or harm us. Certain bugs, like Salmonella typhi, have long been known to irritate the intestinal tract and increase histamine release in immune cells. Some organisms used as probiotics (like Lactobacillus casei and Lactobacillus d. bulgaricus) may also build up gut histamine levels. In someone with histamine intolerance, this may lead to a rise in histamine-associated complications.

A healthy microbiome is essential to support your body’s response to histamine. Intestinal microbes have been shown to assist in digesting foods, produce beneficial nutrients, and train immune cells to have healthy responses to foreign invaders. When the intestinal environment is calm, the intestinal cells produce a healthy level of DAO. With adequate DAO production, a healthy level of histamine exists in the intestinal tract.

The probiotic strains in ProBiota HistaminX Powder help lessen your DAO enzyme’s workload by excluding species known to produce histamine. This unique probiotic also supports your gut’s natural response to food-derived histamine. It promotes a normal inflammatory response in the body, which in turn lessens your DAO enzyme’s workload. It’s never been easier to support a healthy microbiome and balanced histamine levels!

ProBiota HistaminX Powder
Supplement Facts

Serving Size: 1 Scoop (0.39g)
Servings Per Container: 60

Probiotic Blend 197 mg **
Bifidobacterium infantis
Bifidobacterium bifidum
Bifidobacterium longum
Lactobacillus salivarius
Lactobacillus plantarum
Bifidobacterium lactis
Bifidobacterium breve
 Total Cultures 25 Billion CFU
**Daily Value (DV) not established.

Other Ingredients: None

At the time of manufacturing.

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Powder
  • How To Store: Refrigerate and keep tightly closed to maintain maximum potency.

    This product does not require an ice pack during shipping, click here to learn more

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use ProBiota HistaminX Powder

Suggested Use

Take 1 scoop any time of day with food. You may sprinkle or mix in food or drink. Use as directed by your healthcare professional.


Children and pregnant or lactating women should consult their healthcare professional prior to use. Keep out of reach of children.

Constipation or shifts in bowel movements may occur when first beginning a probiotic regimen. If this happens, stop taking ProBiota HistaminX Powder until normal bowel movement occurs. If bowel movements do not return to normal, stop use and consult a healthcare professional.

FAQs for ProBiota HistaminX Powder

What is the purpose of each ingredient in ProBiota HistaminX Powder?

Ingredients Purpose
Bifidobacterium bifidum, bifidobacterium longum, bifidobacterium lactis, bifidobacterium breve, bifidobacterium infantis, lactobacillus salivarius, lactobacillus plantarum Support healthy microbiome bacteria

What strains are contained in ProBiota HistaminX Powder, and in what amounts?

The amounts of each strain and strain numbers are proprietary. ProBiota HistaminX Powder is 100% strain-specific to maintain consistency from lot to lot.

You can see the species that are included in ProBiota HistaminX Powder here: Probiotic Supplement Comparison Chart.

Which histamine product is right for me?

Click here to view our Histamine Supplement Comparison Chart.

We wrote an article sharing our Top 5 Histamine Intolerance Products.

If you have a question that's not addressed
here, see all frequently asked questions.


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What our customers say

Real reviews from real customers.

Rated 4.8 out of 5 stars
Based on 25 reviews
Total 5 star reviews: 23 Total 4 star reviews: 1 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 1
96%would recommend this product
25 reviews
  • DR Profile picture for Deiyi logo
    Deiyi R.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Histamina estable

    Gran probiótico que no eleva mis niveles de histamina, me encanta la forma en polvo, tiene un buen sabor.

  • MB Profile picture for Melissa B.
    Melissa B.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago

    This probiotic is perfect and it never gives me trouble, ever! The only trouble I have is when I don’t take it!

  • S
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    4 months ago
    Support for healthy skin and overall wellness.

    This probiotic has been very supportive for my family. My son is taking it to support histamine intolerance he has been dealing with. I recently started it because I need additional support for healthy skin. I'm noticing benefits in my skin, as well as in my gut and seasonal sensitivities. Very thankful for this product so we can support our gut health without irritating histamine intolerance symptoms.

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These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.