Optimal Sleep II* - 60 Capsules

Rated 5.0 out of 5
Based on 3 reviews

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Key Benefits and Actions*

  • Supports healthy onset of sleep for occasional sleeplessness
  • Promotes healthy metabolism of dopamine, epinephrine, and norepinephrine for feelings of calm and relaxation
  • Great for those with slower MAOA or COMT enzymes

Do you stare at the ceiling at night, counting sheep? If you struggle to fall asleep on occasion, you may benefit from nutrients that support your body’s ability to calm down, relax, and produce melatonin.*

Healthy sleep requires balanced brain chemistry. This relies on the proper metabolism of catecholamines (dopamine, norepinephrine, and epinephrine). This is because catecholamines are responsible for feelings of excitement, nervousness, and anger, which can all interfere with restful sleep.*

Optimal Sleep II* is a powerful vitamin, mineral, and herbal formula intended to support the healthy onset of sleep.*

Unlike our original Optimal Sleep* formula (intended for people with faster MAOA and COMT enzymes), this product is designed for those who feel that their MAOA and COMT enzymes are working slower (see Dirty Genes or StrateGene® to learn your MAOA and COMT status). Due to genetics or epigenetics, slower MAOA and COMT enzymes can contribute to the build-up of excitatory brain chemicals.*

This formula supplies the necessary nutrient cofactors for healthy neurotransmitter metabolism to support optimal sleep. These targeted nutrients serve as cofactors for enzymes that break down excitatory brain chemicals (such as dopamine) and potentially toxic byproducts (such as ammonia). They also support the metabolism of serotonin for those who may have a build-up of this neurotransmitter.*

The targeted nutrients found in Optimal Sleep II* support your ability to calm down and fall asleep on those occasional sleepless nights:*

  • Riboflavin: Cofactor for the MAOA enzyme which helps to metabolize dopamine for feelings of calm
  • Magnesium: Cofactor for the COMT enzyme to support the breakdown of dopamine, epinephrine, and norepinephrine
  • Lithium & Vitamin B6: Support glutamate metabolism and feelings of calm
  • Ornithine: Helps reduce ammonia production caused by neurotransmitter breakdown, as ammonia can lead to excitation in the brain
  • Thiamine, Zinc & Niacin: Cofactors for the ALDH2 and ADH1B enzymes to support the breakdown of potentially toxic DOPAL, DOPEGAL, and other aldehydes

Each of these key nutrients was specifically selected to target the enzymes and processes responsible for producing healthy sleep. If you find yourself struggling to calm down after crawling into bed, Optimal Sleep II* might just be the perfect partner for your nighttime routine.*

Suggested Use

Take 2 capsules away from food 30 minutes prior to bedtime, or use as directed by your healthcare professional.


Children and pregnant or lactating women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged.

Allergy and Diet Information

  • Optimal Sleep II* is suitable for vegetarians and vegans
  • Optimal Sleep II* is free of milk, egg, fish, shellfish, tree nuts, peanuts, wheat, soy, gluten, GMOs, artificial colors, artificial flavors
  • Optimal Sleep II* meets or exceeds cGMP Quality Standards

When taking Optimal Sleep II*, consider these complementary products as recommended by Dr. Ben Lynch:

  • SAMe: S-adenosylmethionine (SAMe) is a cofactor for the COMT enzyme, responsible for breaking down excitatory brain chemicals to support healthy feelings of calm.*
  • PQQ: This nutrient has antioxidant properties that help support a healthy glutamate response in the brain for healthy cognitive function.*
  • Optimal Adrenal: The herbs and nutrients in this vegan formula support adrenal gland function and feelings of calm.*
  • Adrenal Cortex: This powerful glandular extract may help support energy production in the morning by providing building blocks for cortisol.*

Serving Size: 2 Capsules
Servings Per Container: 30

Thiamin (as thiamine hydrochloride) 5 mg 417%
Riboflavin (as riboflavin 5'-phosphate sodium) 5 mg 385%
Niacin 15 mg 94%
Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg 294%
Magnesium (as DiMagnesium Malate§ and magnesium acetyl taurine) 125 mg 30%
Zinc (as Zinc Bisglycinate Chelate§) 7 mg 64%
L-Ornithine hydrochloride 160 mg **
KSM-66 Ashwagandha Extract (Withania somnifera)(root)(5% total withanolides) 125 mg **
Phosphatidylserine 25 mg **
Lithium (as lithium orotate) 2.5 mg **
**Daily Value (DV) not established.

Other Ingredients: Vegetarian capsule (hypromellose and water) and ascorbyl palmitate.

Learning Center Find product FAQ and more! Click here.
Cost Per Serving $0.87
Delivery Method Vegetarian Capsule
Capsule Size 0
Storage Keep closed in a cool, dry place out of reach by children.
Age Suitability Adult
Manufactured In USA
Case Quantity 24
Dimensions (in.) Length: 2.375 / Width: 2.375 / Height: 4.25
Weight (lb.) 0.2500
Barcode 810007521671
Return Policy Learn more about our Return Policy.

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average rating 5.0 out of 5
Based on 3 reviews
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100% of reviewers would recommend this product to a friend
3 Reviews
Reviewed by Melissa C., from United States
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

So far so good

Seems to be okay. I am noticing it takes less time to fall asleep at night & my sleep seems more restful however my deep sleep seems to be declining - it could be something else that's causing this so I will test it out some more.

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Reviewed by Linda L., from United States
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Optimal sleep II capsules

I like the Product as it helps me fall asleep and stay asleep. I will be ordering the product again.

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Reviewed by Katie M., from United States
Verified Buyer
I recommend this product
Rated 5 out of 5
Review posted

Best Sleep Hack Yet!

After years of living on the graveyard shift & then returning to a day shift I have struggled to reset my circadian rhythm. Supplementing with melatonin has never worked for me. Optimal Sleep ll has been a game changer for me. After a few weeks using this I have much better deep sleep and wake up less often. My Fitbit scores show a clear change in my sleep patterns. I highly recommend this product!

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