Optimal Sleep II* - 60 Capsules

Rated 3.9 out of 5
Based on 22 reviews

List price: $

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Key Benefits and Actions*

  • Supports healthy onset of sleep for occasional sleeplessness
  • Promotes healthy metabolism of dopamine, epinephrine, and norepinephrine for feelings of calm and relaxation
  • Great for those with slower MAOA or COMT enzymes

Do you stare at the ceiling at night, counting sheep? If you struggle to fall asleep on occasion, you may benefit from nutrients that support your body’s ability to calm down, relax, and produce melatonin.*

Healthy sleep requires balanced brain chemistry. This relies on the proper metabolism of catecholamines (dopamine, norepinephrine, and epinephrine). This is because catecholamines are responsible for feelings of excitement, nervousness, and anger, which can all interfere with restful sleep.*

Optimal Sleep II* is a powerful vitamin, mineral, and herbal formula intended to support the healthy onset of sleep.*

Unlike our original Optimal Sleep* formula (intended for people with faster MAOA and COMT enzymes), this product is designed for those who feel that their MAOA and COMT enzymes are working slower (see Dirty Genes or StrateGene® to learn your MAOA and COMT status). Due to genetics or epigenetics, slower MAOA and COMT enzymes can contribute to the build-up of excitatory brain chemicals.*

This formula supplies the necessary nutrient cofactors for healthy neurotransmitter metabolism to support optimal sleep. These targeted nutrients serve as cofactors for enzymes that break down excitatory brain chemicals (such as dopamine) and potentially toxic byproducts (such as ammonia). They also support the metabolism of serotonin for those who may have a build-up of this neurotransmitter.*

The targeted nutrients found in Optimal Sleep II* support your ability to calm down and fall asleep on those occasional sleepless nights:*

  • Riboflavin: Cofactor for the MAOA enzyme which helps to metabolize dopamine for feelings of calm
  • Magnesium: Cofactor for the COMT enzyme to support the breakdown of dopamine, epinephrine, and norepinephrine
  • Lithium & Vitamin B6: Support glutamate metabolism and feelings of calm
  • Ornithine: Helps reduce ammonia production caused by neurotransmitter breakdown, as ammonia can lead to excitation in the brain
  • Thiamine, Zinc & Niacin: Cofactors for the ALDH2 and ADH1B enzymes to support the breakdown of potentially toxic DOPAL, DOPEGAL, and other aldehydes

Each of these key nutrients was specifically selected to target the enzymes and processes responsible for producing healthy sleep. If you find yourself struggling to calm down after crawling into bed, Optimal Sleep II* might just be the perfect partner for your nighttime routine.*

Suggested Use

Take 2 capsules away from food 30 minutes prior to bedtime, or use as directed by your healthcare professional.


Children and pregnant or lactating women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged.

Allergy and Diet Information

  • Optimal Sleep II* is suitable for vegetarians and vegans
  • Optimal Sleep II* is free of milk, egg, fish, shellfish, tree nuts, peanuts, wheat, soy, gluten, GMOs, artificial colors, artificial flavors
  • Optimal Sleep II* meets or exceeds cGMP Quality Standards

When taking Optimal Sleep II*, consider these complementary products as recommended by Dr. Ben Lynch:

  • SAMe: S-adenosylmethionine (SAMe) is a cofactor for the COMT enzyme, responsible for breaking down excitatory brain chemicals to support healthy feelings of calm.*
  • PQQ: This nutrient has antioxidant properties that help support a healthy glutamate response in the brain for healthy cognitive function.*
  • Optimal Adrenal: The herbs and nutrients in this vegan formula support adrenal gland function and feelings of calm.*
  • Adrenal Cortex: This powerful glandular extract may help support energy production in the morning by providing building blocks for cortisol.*

Serving Size: 2 Capsules
Servings Per Container: 30

Thiamin (as thiamine hydrochloride) 5 mg 417%
Riboflavin (as riboflavin 5'-phosphate sodium) 5 mg 385%
Niacin 15 mg 94%
Vitamin B6 (as pyridoxal 5'-phosphate) 5 mg 294%
Magnesium (as DiMagnesium Malate§ and magnesium acetyl taurine) 125 mg 30%
Zinc (as Zinc Bisglycinate Chelate§) 7 mg 64%
L-Ornithine hydrochloride 160 mg **
KSM-66 Ashwagandha Extract (Withania somnifera)(root)(5% total withanolides) 125 mg **
Phosphatidylserine 25 mg **
Lithium (as lithium orotate) 2.5 mg **
**Daily Value (DV) not established.

Other Ingredients: Vegetarian capsule (hypromellose and water) and ascorbyl palmitate.

Learning Center Find product FAQ and more! Click here.
Cost Per Serving $0.87
Delivery Method Vegetarian Capsule
Capsule Size 0
Storage Keep closed in a cool, dry place out of reach by children.
Age Suitability Adult
Manufactured In USA
Case Quantity 24
Dimensions (in.) Length: 2.375 / Width: 2.375 / Height: 4.25
Weight (lb.) 0.2500
Barcode 810007521671
Return Policy Learn more about our Return Policy.

We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback!

average rating 3.9 out of 5
Based on 22 reviews
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82% of reviewers would recommend this product to a friend
22 Reviews
Reviewed by Megan B., from United States
Verified Buyer
I don't recommend this product
Rated 2 out of 5
Review posted

Unrestful Sleep

I took 1 before bed and had very unrestful sleep. My heart was pounding pretty fast all night, so I'm not sure what happened. Possibly from the B vitamins? Hard to say, but I know B1 and B6 do have a noticable energy affect on my body. Maybe I will try again, but not sure I'll want to. I realize some people may benefit, but I'm probably not one of them. I'm finding just taking magnesium before bed, helps me most.

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Seeking Health

Hi Megan, thank you for the feedback! We do offer a 60-day money-back guarantee if you find that this product does not work for you. One of our customer service representatives will reach out to you to see if we can be of further assistance.

Reviewed by Tricia B., from United States
Verified Buyer
I recommend this product
Rated 3 out of 5
Review posted

Tried it once

Normally I have fantastic results with all of these supplements and I'm sure there's a reason why I didn't with this yet. I tried it with optimal sleep 1 and woke up with the worst TMJ of my life for about three weeks. I don't know if it made me clench and grind my teeth but I'd like to figure this out and start small taking it alone without the first optimal sleep. Just a bit hesitant now that my jaws finally healed. I'm sure there's a reason ...we are all different too so I can't recommend or not recommend this

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Seeking Health

Hello, apologies this item did not yield the results you wanted, we are here at customer@seekignhealth.com for any info or help you may need further. Thanks!

Reviewed by Momof4boys, from United States
Verified Buyer
I recommend this product
Rated 4 out of 5
Review posted

Good sleep is not a quick fix...hoping this helps in the long run

I find it difficult to accurately review this supplement but I'll give an honest opinion. I've had many (20+) years of interrupted sleep at night...4:30 am seems to be the common wake-up cycle for me. I know that it cannot be corrected with one capsule a night in one month's time, but I'm giving it a try. I also wonder if the Optimal Sleep regular would be better suited for my issues? I've not had any adverse issues - just trying a comprehensive approach to better sleep.

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