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Histamine Block

Choose 30 or 90 Capsules

Key Benefits and Actions*

  • May help support digestion of food-derived histamine in the digestive tract
  • Enhances the presence of diamine oxidase (enzyme) in the digestive tract
  • Patented material with optimized stability
  • May help support normal inflammatory responses in the digestive tract

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Availability: In stock

Product Name Price Qty
Histamine Block 90 ct.
Histamine Block 30 ct.
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Our return policy covers full refunds or replacements on items within 30 days of purchase.


NOT Suitable for Vegans and Vegetarians



Free of:

Dairy, Egg, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, Soy

Histamine Block by Seeking Health contains a patented enzyme formula providing 10,000 HDU of diamine oxidase (DAO) - the main enzyme responsible for the degradation of ingested histamine - per capsule. Histamine is known as a biogenic amine, an organic nitrogen compound, involved in certain immune responses and found in mast cells. It may be involved in regulating healthy function in the GI tract as well as the nervous system. Histamine also plays an important role in triggering the body’s normal inflammatory response.

An excess of histamine can be problematic, however, leading to histamine sensitivity/intolerance, digestive concerns, allergies and more. Individual sensitivity to histamine varies, and some individuals may be more reactive to histamines and other biogenic amines in foods. Diamine oxidase (DAO) has been clinically tested and found to break down food-derived histamine in the digestive tract. DAO is not absorbed and does not have systemic activity. Histamine Block does not manage or address antibody-related or IgE-related food allergies.*

To help maintain your body's natural first line of defense against ingested histamine - your gut - try ProBiota HistaminX.

Suggested Use

Take 1 to 2 capsules no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare professional.


Children and pregnant or lactating women should consult their healthcare practitioner prior to use. This product contains an ingredient derived from porcine (pig). Avoid if allergic to pork or any other ingredient. Histamine Block is NOT EFFECTIVE for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease. DAO is not absorbed and does not have systemic activity. Histamine Block does not manage or address antibody-related or IgE-related food allergies.

Serving Size: 1
Servings Per Container: 30 or 90

Supplement Facts

Vitamin C (ascorbic acid)10 mg33%
Diamine Oxidase (from porcine kidney protein concentrate)4.2 mg (10,000 HDU)**
% DV (Daily Value) based on standard 2,000 calorie daily intake
**Daily Value not established

Other Ingredients: Microcrystalline cellulose (plant fiber), HPMC (capsule), sucrose, rice starch, shellac, hydroxypropylcellulose, crospovidone, hydrated magnesium silicate, sodium carboxymethylcellulose, and glycerol.

Additional Info
Additional Info
Learning Center Find product FAQ and more! Click here.
Delivery Method Vegetarian Capsule
Storage Keep tightly closed in a cool, dry place out of reach by children.
Age Suitability Adult
Manufactured In USA
Case Quantity 24
Dimensions (in.) Length: 2.00 / Width: 2.00 / Height: 3.75
Return Policy 30 Day Returns ― Learn more about our Return Policy.
Customer Reviews (11)
Most helpful!
This product helped my reacting to everything son to feel better and be able to eat more foods. Good quality products make all the difference! Grateful to have found this and I have looked high and low. Review by Maria (Posted on 8/11/2018)
Great product!
Works well! A lifesaver when eating out. My reason for the 4 stars is I don't like the thought of putting shellac into my body but I guess the benefits outweigh the negatives! Review by Karen (Posted on 8/9/2018)
It works!
Between this and Probiotic Histaminix I am able to eat more of the foods I like. Thank you! Review by Susan (Posted on 8/1/2018)
These have helped a lot with my allergies! Review by Todd (Posted on 7/31/2018)
Helped Calm
I had taken a few doses and didn't notice any changes initially but as I continued taking it I really started to notice feeling better overall. A calm feeling that I didn't realize I had not felt for years. I have several genetic SNPs that are heterozygous regarding DAO so it is something I will continue to take the rest of my life. Review by Lee Ann (Posted on 4/15/2017)
Very upset this is out of stock, this is the best DAO out there
Without this product I get headaches, hives, rashes, stomach upset, inflammation, weeping eyes, aches and pains and I cannot eat many foods. This has enabled me to enjoy eating out again and even eating normal foods like everyone else period. I have tried every brand of DAO on the market. This is by far the very best. I hope it will come back in stock soon. This product changed my life in the best possible way. Thank you Seeking Health for making such a great product. I hope you can get it back in stock soon. Review by Best DAO (Posted on 3/21/2017)
added benefits!
I started taking this for my HIT symptoms, especially for dry skin on my face. Not only does it help my dry, flaky skin, but my energy levels rose tremendously, and my mind was much clearer! I really notice a difference with this product. Even when I am eating a HIT diet, this still helps with my energy and mind. Review by loretta (Posted on 3/2/2017)
Life Changer
My daughter age 13 has been taking Histamine Block for 8 months. She takes between 2 to 4 pills a day. She takes one pill every morning & one pill anytime she has a food that is high in histamine. It has changed her life! She has been able to eat out at restaurants multiple times without nausea or headache. Also when she does have a headache or migraine she takes a histamine block & it reduces the severity & time of the headache/migraine. It really has helped her! Can't say enough positives about this product! Hopefully it will be available again soon! Review by Scubadadseattle (Posted on 2/28/2017)
Can't get enough of it
DAO has helped my headaches and, surprisingly, my sleep. I just recently explored the possibility that I have a surplus of histamine (or "histamine intolerance"), and the positive impact of this product strengthens this hypothesis.

Thanks for being so innovative, Seeking Health!
Review by Trish (Posted on 2/23/2017)
Important supplement
I have MCAS and DAO has given me back my life, in terms of eating. It is so important to have access to good brands! Thank you! Review by E (Posted on 2/8/2017)
awesome product
This product has helped to decrease back pain, rash, inflammation, bloat, etc. due to histamine intolerance. I wish it were cheaper, just as everyone else, but this could possibly be a life changer for people with HIT. PLEASE don't ever stop making this product! Thank you! Review by Mandy (Posted on 1/10/2017)
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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