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HomocysteX Plus

60 Capsules

Key Benefits and Actions*

  • Provides active B vitamins in potent doses
  • May help support healthy methylation processes
  • May help support normal homocysteine conversion
  • May help support cognitive health

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$27.95

Availability: In stock

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Details
Details

Suitable for Vegans and Vegetarians

Free of:

Dairy, Egg, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, Soy, Gluten, GMO


HomocysteX Plus by Seeking Health supplies bioactive forms of four essential B-vitamins together with betaine (also known as trimethylglycine or TMG) to synergistically support methylation processes and normal homocysteine metabolism. The body's methylation process is vital for formation of essential cell components such as proteins, nucleic acids found in DNA and RNA, and phospholipids that form nerve cell membranes. By transferring methyl groups (three hydrogen atoms bonded to a carbon atom, known as CH3) from one molecule to another, methylation turns on genes, activates enzymes, drives detoxification reactions, influences hormone secretion, and helps maintain normal metabolism of homocysteine, a potentially harmful amino acid metabolite. Unfortunately, poor nutrition, oxidative stress, infections, metabolic defects, and various other factors can impair methylation processes throughout the body.*

To nutritionally support optimal methylation capacity, this product supplies folate, vitamin B12, B6, B2, and betaine in amounts and forms that are efficiently utilized and well-tolerated by the body. Taking just L-5-methylfolate is often times not sufficient for those with MTHFR mutations. Dr. Lynch provides these other ingredients, such as betaine (TMG), to help support healthy homocysteine levels and support the methylation cycle.*

Betaine is a powerful and important methyl donor for the body, especially for those who have MTHFR mutations. Vitamin B12 is crucial to the formation of healthy red blood cells, energy production, nervous system support, cognitive function, and homocysteine regulation. Vitamin B6 as P-5-P is important as a coenzyme for the normal metabolism of amino acids, carbohydrates and lipids. It is also involved in healthy cognitive development, immune health and homocysteine conversion. Riboflavin is important for body growth and red blood cell production and assists in the process of releasing energy from carbohydrates.*

For a methylation support supplement without the betaine, consider our HomocysteX. For a B12- and folate-only product, consider our Active B12 with L-5-MTHF or our Optimal Liposomal Active B12 with L-5-MTHF.

Suggested Use

Take 1 capsule daily after breakfast, or as directed by your healthcare professional.

Warnings

Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Consult with a healthcare professional before use if you are using antibiotics or other medications.

Serving Size: 1 Capsule
Servings Per Container: 60

Supplement Facts

AMT %DV
Riboflavin (as riboflavin-5’-phosphate sodium) 25 mg 1923%
Vitamin B6 (as pyridoxal-5’-phosphate) 15 mg 882%
Folate (as Quatrefolic (6S)-5-methyltetrahydrofolate, glucosamine salt) 800 mcg DFE 200%
Vitamin B12 (50% as methylcobalamin and 50% as adenosylcobalamin) 1000 mcg 41667%
TMG (trimethylglycine) 700 mg **
% DV (Daily Value) based on standard 2,000 calorie daily intake
**Daily Value not established

Other Ingredients: HPMC (capsule), ascorbyl palmitate, silica, and medium chain triglycerides.

Additional Info
Additional Info
Learning Center Find product FAQ and more! Click here.
Cost Per Serving $0.47
Delivery Method Vegetarian Capsule
Capsule Size 0
Storage Keep closed in a cool, dry place out of reach by children.
Age Suitability Adult
Manufactured In USA
Case Quantity 24
Dimensions (in.) Length: 2 / Width: 2 / Height: 3.75
Weight (lb.) 0.2000
SKU HOMOP-60-CAPS
Barcode 700580723534
Return Policy 30 Day Returns ― Learn more about our Return Policy.
Reviews
Customer Reviews (83)
Good if you don't have additional mutations like me
Quality
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Effectiveness
I have tried quite a few of Seeking Health's products. I find them all to be very effective. And, in this case, too affective. I am slowly working through Dr. Lynch's recommendations. This has RADICALLY changed my life. When I got to this product I got seriously agitated. So, I backed down to Homosystex. I knew there had to be a reason why I wasn't able to tolerate it. I also have the same reaction to most liver support supplements. It was when I was taking Dr. Lynch's Introduction to Nutrigenomics that I realized another mutation I have doesn't do well with TMG. I'm adding this in case you don't tolerate this supplement go back and check your other mutations.
Review by Gretchen (Posted on 12/22/2014)
Review by Marcia
Quality
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Effectiveness
Let me preface this review by stating that I really LIKE the "clean supplements" from Seeking Health. I am homozygous 677 for the MTHFR gene and have been taking Methyl B12 lozenges and Methylfolate, both from Seeking Health for less than a month. I ordered HomocysteX Plus because I felt it would be more convenient to have the Bs together in one capsule. However, I discovered that I don't seem to react well to the TMG in it. I tried taking 1/4 of the HomocysteX Plus capsule daily, and realized I would then not be getting enough of the Bs. I even tried going back to my separate Bs from Seeking Health and adding a pinch of another brand of TMG powder. I know it SHOULD work for those with my mutation, and I desperately wanted that TMG to potentially lower my high homocysteine levels. However, I was getting some strange side effects. TMG is a pretty powerful methyl donor, and perhaps my 66-year-old body can't handle it at this point. I will probably be ordering the regular Homocystex, which doesn't contain the TMG. Review by Marcia (Posted on 12/14/2014)
homocystex plus
Quality
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Effectiveness
I have been taking this for just over a month, and have just increased to 2 capsules a day. I'm homozygous c677t with depression, anxiety and hypothyroid. I feel like it might be calming me down a bit. I'm going to stick with it for awhile and see what happens. Review by Julie (Posted on 7/10/2014)
The easy way
Quality
Purity
Effectiveness
This is the easiest way to get my B12 and Folate needs satisfied with the right increments and with the proper Methy form. I would reccomend this product. And, believe me, I looked all over. Review by Debbie (Posted on 6/22/2014)
Very thankful for Seeking Health!
Purity
Effectiveness
Quality
I made a youtube of my review. You can see it here: http://youtu.be/884X0HhN_nY

Review by marilyn (Posted on 5/25/2014)
Great product
Purity
Effectiveness
Quality
I was so happy to find a product with the methyl form of multiple B vitamins, rather than taking multiple products! It is a great product! Review by jo (Posted on 5/24/2014)
Looking for correct amount to take
Purity
Effectiveness
Quality
I am homozygous C677t, but other than some mild depression, have had minimal emotional effects. Started taking prescription Cerefolin NAC, but was concerned I was getting too much folate, so am trying this. The Cerefolin dropped my homocysteine levels considerably, will find out soon if the lower dose is working as well. Review by Bill (Posted on 5/6/2014)
Working great for me!!
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Effectiveness
So glad I found this! Working amazing for me and the cost is super reasonable. Review by Diana (Posted on 5/1/2014)
thank you!
Quality
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Effectiveness
I just started taking this not too long ago, but have had amazing results. Being homozygous c677t, I highly recommend this for people with mthfr! Give it a try! Thank you seeking health and Dr. Lynch! Review by kimberly (Posted on 4/6/2014)
This is a very effective product for me.
Purity
Effectiveness
Quality
I have MTHFR and have been taking homocystex for over a year now. I used to take Metanax but changed to your product. It is working very well. Review by Mell (Posted on 9/17/2013)
Simply the BEST!
Purity
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Quality
I am homozygous for C677T and this is hands-down the best supplement. I take at least two/day and offset over-methylation with Seeking Health Niacin. Review by HELEN (Posted on 8/20/2013)
Has Made All The Difference
Quality
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Effectiveness
About a month ago, I was looking for answers as to why I was feeling so tired all the time. I found out I had Candida, which let me to an article Dr. Lynch had written regarding Candida interfering with proper methylation. Wow, what a difference. I am currently up to 2 capsules a day, 1 at breakfast and 1 before lunch, and they have been a huge help in my overall energy. Just ordered 2 more bottles and am getting my genes tested to see if I have any mutations. Thanks so much Dr. Lynch for formulating this great product! Review by Jake (Posted on 4/29/2013)
Caused Acne
Quality
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I have the MTHFR gene and realize the importance of supplementing with the appropriate vitamins. Unfortunately, this supplement has caused me to suffer from severe acne and Rosacea. I've gone off and on the supplement and every time I go back on I break out. I researched and found it is not uncommon for B12 and B6 to cause acne. I would love to know why this is happening and what my options are?

NOTE FROM DR LYNCH:
B12, B6 and Folate are all phase 1 liver support nutrients. If your phase 2 liver support is deficient, symptoms of acne may occur. Consider supporting phase 2 liver support prior to restarting HomocysteX Plus. Phase 2 liver support is found in MSM, NAC, Taurine, Liver Nutrients, Arginine, Glutamine, Methionine, Glycine. Supporting antioxidants may also help - such as vitamin E, C, D, selenium, alpha lipoic acid, CoQ10, zinc
Review by mon (Posted on 4/19/2013)
Great Product
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Quality
I have been taking Homocystex Plus for a couple of months due to the fact I have the defective MTHFR gene (I am also clinically depressed). I lost 10 pounds and plan to try 2 capsules per day to see if I have more energy and feel better. Review by Andrea (Posted on 2/24/2013)
LOVE!!!
Effectiveness
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Could definitely see IMMEDIATE changes in my energy level! I was hesitant taking it on an empty stomach first thing in the morning, but I've had no problems with nausea. HomocysteX, where have you been all my life?! Review by Helen (Posted on 4/17/2012)
Wonderful Product!
Effectiveness
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My two children and I have MTHFR and have been using Metanx. I purchased HomeosysteX Plus and L-5-MTHF 1000 to replace Metanx. Very pleased with the results. Feel like it does a better job than Metanx. Review by Jeannie (Posted on 4/17/2012)
Thank you Dr. Lynch
Effectiveness
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I took a bottle of HomocysteX to my doctor's appt. My doctor looked at the ingredients with interest. He was very impressed with the ingredient list of HomocysteX Plus. I so appreciate this supplement,
there is nothing else like it.

# 167676
Review by SuzieQ (Posted on 4/17/2012)
Great Product
Effectiveness
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Quality
Our family has been on a variety of prescription Metafolate. I was a bit confused to see the fillers and artificial colors in these products. My understanding is that Metafolate can help people with the MTHFR gene detox. It made sense to me to avoid things that hindered detoxing. I so appreciate Homocystex! It contains what I need without artificial fillers or colors.

Order # 164778
Review by tobysmom (Posted on 4/17/2012)
Not Good for People with Reynauds
Effectiveness
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I am homozygous for MTHFR so i thought this would be an excellent product for me. In addition to the MTHFR problem i also suffer from Reynaud's syndrome. I am very careful about cold exposure and have very few bouts normally. Once I started taking the Homocystex, I started having bouts in both my hands and feet several times a day. I RARELY get them in my feet. I stopped the Homocystex and immediately the bouts stopped, but once i tried taking the Homocystex again they returned. Unfortunately I wasted $27.95 to find out. I hope my experience can help someone else. I will be going back to high doses of Folinic acid (Leucovorin), which helped with my energy level and did not bring on Reynaud's issues. I wish this product had worked for me:(

Order # 100018392

COMMENT FROM DR BEN:
Sorry to hear that HomocysteX did not work well for you. HomocysteX is a potent product - and when used by people having the right biochemistry - works amazingly well.

Some people - especially those homozygous A1298C - do not seem to do well with HomocysteX. This is likely because they are already methylating fairly well but not getting enough BH4. Having worked with many with A1298C, I have found that HomocysteX does not work well for them. This is not a blanket statement as there are life circumstances, other mutations and environmental factor in play which cause a variation from person to person and this causes some things to work well for some and not for others.

Raynauds tends to do well with increased niacin, magnesium, stress relievers, contrast hot/cold therapy, healing the gut, vitamin D3 to name a few.

For people who are already over methylated, HomocysteX is not for them. A good way to see if you are over methylated is to check your histamine levels. Low histamine = overmethylated according to Dr Pfeiifer.
Review by jusmeamom (Posted on 4/17/2012)
Great Product!
Effectiveness
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Quality
This is a very complete product. I have been taking only B-12 and Folic Acid in the methyl forms. I did not realize how important it is to have B-6 and the other ingredients in this product. It makes a world of difference in the way it makes me feel. Thanks for all the great information as well.

Order # 155418
Review by Lynn (Posted on 4/17/2012)

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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