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Histamine Digest - BOGO


Quality DAO Supplement

  • Digests histamine fast using the patented DAOgest® enzyme
  • Eat and drink with confidence again!
  • Supports healthy histamine levels in the small intestines, colon, uterus, bladder, prostate and breast milk.

Third Party Tested

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60-day Return Policy

High End Ingredients

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Amazing Products

This product has been a game changer for us. My daughter can enjoy food so much more and road trips are no longer nearly as stressful. We take the Histamine Digest everywhere! ~ Esquibel F.

Can’t digest histamine?

Histamine Digest can do it for you.

Now you can eat and drink with confidence.

Assess each statement below. If you relate any of them, then Histamine Digest may help you support healthy histamine levels:

  • After eating or drinking, I often feel worse but not sure why.
  • I have been told that I have a leaky gut. I want to support a healthy gut lining.
  • I’m breastfeeding and I notice my baby experiences colic when my diet consists of histamine containing foods or drinks.
  • I’m pregnant and experiencing morning sickness, nausea and vomiting of pregnancy.
  • I would love to support a healthy, comfortable menstrual cycle.
  • I noticed that when I was pregnant, my histamine intolerance was basically gone! Now that I’m not pregnant, my histamine symptoms are back again. So weird!
  • I need Metformin and want to support a healthy histamine response while taking it.
  • My bowel movements are often loose or just inconsistent
  • Certain probiotics make me feel worse - eg. Streptococcus, L. fermentum, L. casei, L. bulgaricus and I want to support healthy balance
  • My gut microbiome is messing with me. I’d like to support a healthy response to my gut microbiome.
  • I have a dirty DAO gene
  • SIBO is troubling me and I believe it’s contributing to my histamine intolerance. I’d like to support healthy histamine levels.
  • I want to enjoy eating and drinking a more varied menu again
  • I eat and drink lots of cured, aged, and fermented products
  • I experience uncomfortable symptoms after having the following foods or drinks (note: you are not allergic to these foods, they just make you feel off):
    • Alcohol, especially red wine or champagne
    • Aged cheeses (eg. Parmesan, Gouda, Swiss, Cheddar)
    • Aged meats (eg. salami, pepperoni, canned meat, sausages, jerky)
    • Fish
    • Tomatoes
    • Sausages
    • Orange juice
    • Pineapple juice
    • Very ripe fruit (eg. strawberries, bananas)
    • Avocados
    • Sauerkraut, Kimchi
    • Balsamic vinegar
    • Kombucha
    • Leftovers
  • I experience a few of the following symptoms after having high histamine foods or drinks
    • Headaches
    • Hives
    • Frequent inappropriate fatigue
    • Difficulty falling asleep
    • Loose stools
    • Bloating, gas
    • Stomach discomfort
    • Bladder discomfort
    • Nausea or pukey
    • Frequent peeing.
    • Waking up to pee at night
    • Ringing in the ears or fluid
    • Bedwetting
    • Heart palpitations or faster heart beat
    • Rashes, itchy skin or eczema
    • Sweating, flushing, red spots on skin or just feel hotter
    • Sneezing or runny nose
    • Irritability
    • Anxiousness
    • Nose bleeds

If a number of those resonated with you, then Histamine Digest is something that you should seriously consider.

If none of the statements above resonated with you, then Histamine Digest is not something you need currently.

Alternatively, consider Histamine Nutrients or ProBiota HistaminX.

Key Ingredients

Inside the Uncompromising Quality of Our Ingredients

  • DAOgest® (Diamine oxidase)
    This patented enzyme, derived from porcine (pork) kidney extract, supports the healthy breakdown of histamine in many areas of your body - especially the small intestine, colon, placenta, kidney, appendix, testis and prostate.

When taken with meals, Histamine Digest helps break down histamine found in foods and drinks. Histamine will be at a healthy level which helps eliminate feelings related to histamine intolerance.†‡

When taken on an empty stomach, Histamine Digest helps break down histamine produced from the microbiome or your gut’s immune system.

This is a great idea to try: Take 1 capsule of Histamine Digest on an empty stomach to see if you feel better within 30 minutes.

Why would this be useful? High amounts of histamine are produced by an unhealthy microbiome, or an overactive gut immune system.

If you feel better, continue using Histamine Digest on an empty stomach as needed. Histamine Digest supports a healthy balance of histamine in the gut.

Histamine Digest may support healthy levels of histamine within the small intestine, colon, kidneys, uterus, appendix, placenta, prostate, or testicles. This is very important as unhealthy levels of histamine within these areas contribute to problems locally or throughout the body.

Children 4 years of age and older may use Histamine Digest. You may need to open the small capsule and mix in a bite of applesauce if they cannot swallow the small capsule.

Breastfeeding women may use Histamine Digest. Histamine gets absorbed from the gut and into breastmilk. If breastmilk has higher levels of histamine, the breastfeeding baby may experience colic. Infant colic is associated with higher levels of histamine. Support healthy levels of histamine in your breastmilk by taking Histamine Digest.

Pregnant women may use Histamine Digest if approved by their healthcare professional. Occasional nausea and vomiting of pregnancy is associated with high levels of histamine. Levels of histamine in a healthy pregnancy decrease below values found in healthy non-pregnant women. This is because the placenta is designed to produce a lot of the DAO enzyme. However, sometimes the levels of histamine exceed the ability of the placenta’s DAO enzyme to digest histamine.

In some complications of pregnancy, maternal blood histamine levels rise above those associated with a healthy pregnancy. Many of the complications of pregnancy, including preeclampsia, preterm labour, spontaneous abortion and hyperemesis gravidarum, are associated with increased levels of maternal blood histamine. Supporting healthy levels of maternal blood histamine levels during pregnancy, especially during such complications, may be helpful.

Suggested Use

As needed, anytime, take 1 capsule before eating or drinking. Alternatively, as needed, take 1 capsule away from food or drink if wanting to support uterine comfort during the menstrual cycle, occasional nausea from pregnancy or healthy histamine levels in your digestive system. Capsules may be opened and sprinkled on a bite of food. Use as directed by your healthcare professional.

Do not take Histamine Digest and knowingly eat foods you are allergic to—it will not prevent allergic reactions.


Consult with your healthcare practitioner prior to use. Do not use if inner tamper seal is damaged.

NOT Suitable for

Vegetarians or Vegans

Delivery Method


How to Store

Keep closed in a cool, dry place out of reach by children.

  • No Artificial Flavors
  • No Artificial Colors
  • Wheat-Free
  • Tree-Nut-Free
  • Shellfish-Free
  • Sesame-Free
  • Soy-Free
  • Peanut-Free
  • GMO-Free
  • Gluten-Free
  • Fish-Free
  • Egg-Free
  • Dairy-Free

Important Note:

Histamine Digest is very effective for providing the DAO enzyme immediately to support your digestive system.

Histamine Digest is known as a palliative supplement. It helps you feel great but it doesn't solve the underlying problem.

Ultimately, you want your body’s DAO enzyme to function well on its own. It takes time to figure out how to heal your gut, restore your microbiome and balance your immune system. Work with a naturopathic physician or integrative health professional to help you work through these areas.

It’s possible to experience relief now. Use Histamine Digest so you can immediately enjoy feeling healthy, instead of struggling, when consuming foods or drinks high in histamine.

Over time, as you work on healing your gut, restoring your healthy microbiome and balancing your immune system, you’ll likely need less Histamine Digest to support healthy histamine metabolism.

Change in bowel frequency may occur from using Histamine Digest.

High amounts of histamine in the gut are associated with loose stools or diarrhea. Low amounts of histamine are associated with constipation. Since Histamine Digest supports healthy histamine levels, if one takes too much, it may contribute to harder to pass stools.

If stools become harder to pass, only use Histamine Digest when eating foods or drinks with histamine.

If you continue having harder to pass stools, then stop using Histamine Digest and consume a histamine-containing drink like kombucha. If you now can pass stools normally again, then you know you may have taken too much Histamine Digest. Adjust your use as needed.

Note that your use of Histamine Digest will reduce as you restore a healthy gut lining and a healthy gut microbiome.

This is why it’s highly recommended to use ProBiota HistaminX each evening after dinner. Probiota HistaminX supports a healthy gut microbiome.

What our customers say

Real reviews from real customers.

Rated 4.8 out of 5 stars
Based on 494 reviews
Total 5 star reviews: 425 Total 4 star reviews: 44 Total 3 star reviews: 12 Total 2 star reviews: 4 Total 1 star reviews: 9
96%would recommend this product
494 reviews
  • DD
    Dedra D.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Life saver

    Could not do without this at this point in life. Thankful to have this product so I can eat.

  • D
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Great product

    I have so many food sensitivities. This supports a healthy response if I happen to have a high histamine food. Bonus, if I take one before bed, it also supports sleep. Thanks Dr. Lynch

  • S
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Histamine Digest

    Supports a healthy response to my histamine sensitivity from various foods.

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