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L-5-MTHF Lozenge - 60 Lozenges

4.8
Rated 4.8 out of 5 stars
85 Reviews
L-5-MTHF Lozenge

L-5-MTHF Lozenge - 60 Lozenges

4.8
Rated 4.8 out of 5 stars
85 Reviews
$18.95 - $96.66
$18.95
You save: $$$ (%)
$18.95 - $96.66
$18.95
You save: $$$ (%)

Key Benefits and Actions†

Key Benefits and Actions†

  • Powerful methylation, MTHFR, and homocysteine support
  • Supports healthy mood and cognition
  • Supports healthy genetic expression

Who Needs L-5-MTHF Lozenge

Methylation controls multiple biochemical pathways in your body.

Your genetics, heart health, hormones, sleep, stress, mood, and detoxification depend on healthy methylation.†

Where does your body get the methyl groups needed to carry out methylation? Primarily from folates that come from food and intestinal microbes. Food folates must be first converted into an active form before your body can use them.

Your MTHFR enzyme converts food folates into the active form of folate, methylfolate. This bioavailable form is also known as L-methylfolate. The true biochemical name is L-5-methyltetrahydrofolate (L-5-MTHF).

Over 50 percent of the population is thought to have a genetic mutation in their MTHFR gene. Thus, they may not be achieving adequate methylfolate levels from food alone.†

Because L-5-MTHF bypasses the MTHFR enzyme, it can provide methylation support for those with MTHFR polymorphisms.†

Folate (as bioavailable L-5-MTHF) is:†

  • Easily absorbed and used by cells
  • The predominant form of folate in circulation
  • The only form of folate that can cross the blood-brain barrier
  • Essential for methylation, DNA expression, homocysteine metabolism, and nervous system function

Bioavailability is particularly crucial when working to replenish folate levels. Ideally, methylfolate is also in a format that supports optimal digestion and absorption, such as a lozenge.†

Seeking Health’s L-5-MTHF Lozenge provides potent methylation support in a delicious, well-absorbed lozenge. Each serving contains 1,700 mcg DFE of methylfolate in the bioavailable form of L-5-methyltetrahydrofolate (L-5-MTHF).†

Our L-5-MTHF Lozenge is naturally sweetened with xylitol. These delicious lozenges deliver folate in a form designed to be rapidly digested for optimal absorption.†

The bioactive form of L-methylfolate (L-5-MTHF) is well-utilized in the methylation cycle. It is often the preferred form for those with methylation, homocysteine, or MTHFR gene mutation concerns.†

Mutations in your MTHFR gene can lead to reduced L-methylfolate production and a less functional methylation cycle. Challenges in the methylation cycle may lead to an increase in homocysteine in the body. Cardiovascular and general wellness are dependent upon maintaining homocysteine levels in the normal range.†

Mutations in this gene can also slow your body’s ability to convert folate into its active forms. Thus, a large majority of people may benefit from consuming an L-methylfolate dietary supplement.† The most direct way to support methylation and MTHFR genetic mutations is with L-methylfolate (L-5-MTHF).†

Supplementing with bioavailable L-5-MTHF supports:†

  • Healthy methylation
  • Positive mood
  • Healthy homocysteine levels
  • Nervous system function and development
  • Prevention of neural tube defects during pregnancy
  • Healthy energy production
  • Normal cognitive, memory, and brain function

Methylation has never tasted so good! Get ready for your methylation cycle to fire on all cylinders with Seeking Health’s L-5-MTHF Lozenge.†

Customer Review

Purest Form

Couldn't find a purest form of b9 elsewhere.. Keep it up team!!! ~AB

Key Ingredients In L-5-MTHF Lozenge

  • L-5-MTHF: A superior form of L-methylfolate that readily donates its methyl groups. It aids conversion of the amino acid homocysteine into methionine and supports your entire methylation cycle.†

Why L-5-MTHF Lozenge Works

Folate plays critical roles in methylation. By donating its methyl groups, folate regulates DNA expression and much more. Without sufficient bioavailable folate, your cells cannot effectively express your genes.†

The MTHFR gene converts food folates into methyl folates. However, MTHFR variations and environmental or lifestyle stress can slow this gene down. If the MTHFR gene is slowed, MTHFR enzyme function is also slowed. The result can be a debilitating folate deficiency.

The artificial version of folate, folic acid, is often prescribed to folate-deficient individuals. Supplementation with L-5-MTHF may be more effective than folic acid supplementation at increasing blood folate levels.†

Folic acid is never included in any of our Seeking Health dietary supplements. This artificial version of folate is not well-utilized by the body and can produce adverse effects. Folic acid must go through several enzymatic steps before it is converted into usable methylfolate. Its inefficient chemical structure may even slow down your SLC191A, DHFR, and MTHFR genes to the point of folate deficiency! Folic acid can also block usable folate from entering your cells, further contributing to folate deficiency.†

By supplementing with the natural form of folate as L-5-MTHF, you bypass the MTHFR enzyme. The methylated form, L-5-methylfolate (L-5-MTHF), requires no additional metabolic steps to be used by the body. This is why it is often the preferred choice for those with folate absorption or metabolic defects.†

L-5-MTHF also supports the production of important mood neurotransmitters. These include dopamine, serotonin, melatonin, epinephrine, and norepinephrine. This is how supplementation with L-5-MTHF can help to support a healthy mood.†

Seeking Heath’s L-5-MTHF Lozenge provides a pure, non-racemic form of L-methylfolate. Each delicious, naturally-flavored lozenge offers a potent dose of 1,700 mcg DFE of folate as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt. This superior form supports healthy methylation, mood, and more.†

Because folate needs B12 to support proper methylation, be sure to pair L-5-MTHF Lozenge with a bioactive form of B12, such as Active B12 1000.†

Now you can go about your day with confidence, knowing your methylation cycle is firing on all cylinders!†

L-5-MTHF Lozenge
Supplement Facts

Serving Size: 1 Lozenge
Servings Per Container: 60

AMT %DV
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt] 1,700 mcg DFE (1,000 mcg) 425%

Other Ingredients: Xylitol, ascorbyl palmitate, natural flavors, and silica.

  • Suitable For: Vegetarians and Vegans
  • Age Suitability: Adults
  • Delivery Method: Lozenges
  • How To Store: Keep closed in a cool, dry place out of reach by children.

Free Of: Eggs, Fish, Gluten, GMO, Milk, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use L-5-MTHF Lozenge

Suggested Use

Take 1 capsule daily, or use as directed by your healthcare provider. Do not take within 5 hours of bedtime as it may interfere with sleep.

Warnings

Children and pregnant or lactating women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged. Consult a healthcare professional prior to use if you are taking any medications or if you are undergoing treatment for any medical condition.

How to Enhance L-5-MTHF Lozenge

1

Consider Pulsing

Dr. Ben Lynch recommends using certain dietary supplements based on your need for them. Start with a partial serving and increase slowly over time to the full serving, only if needed. When you start feeling good, consider reducing the serving size, skipping days, or pausing supplementation. Then take again when you feel you need it (stressful day, traveling, chemical exposure, etc.), hence "pulsing." Work with your qualified healthcare practitioner to determine what's best for you.

2

Pairs Well With

Active B12 5000, provides bioavailable vitamin B12 to support methylation alongside folate.† Optimal Magnesium, to support methylation-dependent enzymes.† PQQ Lozenge, provides antioxidant support to reduce oxidative stress in the methylation pathway.†

3

Clean Your Genes

After years of suffering from unexplainable health issues, Dr. Ben Lynch, ND discovered the root cause - "dirty" genes. In his best-selling book, Dirty Genes, Dr. Ben Lynch describes the steps you can take to promote optimal epigenetic health. Ready to get started? Click here to take the Dirty Genes Quiz to find which of your genes are dirty!

Why Choose Seeking Health

Here at Seeking Health, we are committed to providing you the best in bioavailable supplements, methylation support, prenatal vitamins, genetic analysis tools, and more.

We strive to go above and beyond the average supplement company, which is why we allocate significant resources to testing all of our supplements for purity, potency, and label claims.

  • Third-party tested for heavy
    metals, microbials, and potency
  • Scientifically formulated by Dr. Ben Lynch, ND
  • Manufactured in the USA from globally
    sourced ingredients
  • Nutrients in their bioavailable
    forms for optimal absorption
  • cGMP facility registered by NSF International
Purity & Potency Tested & Assured
Scientifically Formulated by Dr. Ben Lynch
Manufactured in the USA from globally sourced ingredients third-party independently tested
Bioavailable Nutrients

FAQs for L-5-MTHF Lozenge

What is the purpose of each ingredient in L-5-MTHF Lozenge?

Ingredients Purpose†
Folate (Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt) Supports a healthy nervous system, methylation, homocysteine recycling, and prenatal regimen along with a healthy diet and lifestyle

How do I know if taking methylfolate (L-5-MTHF) works? How do I improve its utilization?

L-methylfolate (L-5-MTHF) is a superior form of folate that is well-utilized in the body. This is because 80 percent of the human body's folate is in this form.†

L-5-MTHF is the form of folate that is used for methylation. Methylation is simply when one compound donates a methyl group to another compound. By having a methyl group attached, the compound's function changes.†

You know when L-methylfolate works because of how you feel. It's typically very fast to notice if it's working or not.†

According to Dr. Ben Lynch, supplementing with L-methylfolate can support healthy:†

  • Mental clarity
  • Attention and focus
  • Energy production
  • Vision
  • Memory and recall
  • Circulation, especially in the hands and feet
  • Normal blood pressure
  • Normal homocysteine levels

In order for L-methylfolate to work, it requires vitamin B12. Reduced oxidative stress is also needed for L-methylfolate to function.†

L-methylfolate needs the following to support methylation:†

  • Vitamin B12
  • Zinc
  • Glutathione
  • Reduced oxidative stress
  • Functional MTR enzymes

Talk to your qualified healthcare practitioner before starting methylfolate supplementation. A trained health professional will be able to determine the appropriate dosing and whether methylfolate is right for you.

Which folate is right for me?

Click here to view our Folate Supplement Comparison Chart.

Read this blog: The different forms of folate: which one is right for you?

This blog article explains folic acid side effects.

If you have a question that's not addressed
here, see all frequently asked questions.

VIEW ALL FAQS

Do you have Questions
for this Product?

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What our customers say

Real reviews from real customers.

Product reviews solely reflect the views and opinions expressed by the contributors and not those of SeekingHealth. SeekingHealth does not verify or endorse any claims made in these reviews. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
4.8
Rated 4.8 out of 5 stars
Based on 85 reviews
Total 5 star reviews: 76 Total 4 star reviews: 3 Total 3 star reviews: 5 Total 2 star reviews: 1 Total 1 star reviews: 0
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85 reviews
  • MS
    mary s.
    Flag of United States
    Verified Buyer
    L-5-MTHF Lozenge - 60 Lozenges
    Reviewing
    L-5-MTHF Lozenge - 60 Lozenges
    I recommend this product
    We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback! I understand
    Rated 3 out of 5 stars
    4 months ago
    2 Gripes

    1-Unfortunately, there are no bottle directions on ingestion so I was stymied as to whether to take sublingually, swallow whole, or chew the tablet,

    2-I decided to let it dissolve sublingually but not fond of the taste. Perhaps it's the sugar substitute used.

    Was this helpful?
    SH Profile picture for Seeking Health
    Seeking Health
    3 months ago

    Hello,

    Thank you for the feedback, they are meant to dissolve in your mouth or be chewed. You can find out more about our delivery methods here: https://education.seekinghealth.com/supplement-delivery-methods-whats-best/. We appreciate your feedback in the flavoring profile.

    In Health,
    Seeking Health staff

  • LL Profile picture for Lynnet Lee M.facebook logo
    Lynnet Lee M.
    Flag of United States
    Verified Buyer
    L-5-MTHF Lozenge - 60 Lozenges
    Reviewing
    L-5-MTHF Lozenge - 60 Lozenges
    I recommend this product
    We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback! I understand
    Rated 5 out of 5 stars
    4 months ago
    L-5-MTHF Lozenge - 60 Lozenges

    This has been a daily supplement for me. It has a great fruity flavor and reasonably priced. I appreciate the quality of Seeking Health supplements.

    Was this helpful?
  • EW
    Emily W.
    Flag of United States
    Verified Buyer
    L-5-MTHF Lozenge - 60 Lozenges
    Reviewing
    L-5-MTHF Lozenge - 60 Lozenges
    I recommend this product
    We are not able to publish reviews that reflect atypical results or suggest that any product can diagnose, treat, cure, or prevent any disease, disorder, or chronic health condition. Please be mindful of these restrictions as you leave your review and thank you for all your feedback! I understand
    Rated 5 out of 5 stars
    5 months ago
    Excellent Product!

    This is a great product. I take it for MTHFR, but in general it's great. The lozenge is easy to take and to absorb. It also tastes pretty good.

    Was this helpful?
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†These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.