The benefits of turmeric have been known for centuries. Turmeric has long been used to support a healthy inflammatory response in the body. Many modern-day ailments are thought to have inflammation at their root.†
According to a host of research findings, curcuminoids help to support healthy inflammatory processes. They regulate the master switch of inflammation called Nuclear Factor kappa Beta (NF-κB) or NF𝜅𝛃.†
A long list of conditions can signal cells to up-regulate the body’s inflammatory cascade: bacterial fragments, chemical toxins, inflammatory communication molecules, and even proteins misshapen by excessive blood sugar. Ultimately, this cascade leads to the separation of an inhibitor protein from NF𝜅𝛃. Once free from this inhibitor, NF𝜅𝛃 can migrate to the cell's nucleus. Here, it stimulates the reading of a multitude of pro-inflammatory genes.
In essence, NF𝜅𝛃 is like a switch that turns ‘on’ the inflammatory process inside genes. The curcuminoids in turmeric seem to play a unique role in keeping the inhibitor proteins attached to NF𝜅𝛃. Ultimately, this assists in regulating the inflammatory cascade and moderating normal levels of inflammation.†
Curcuminoids are fat-soluble, polyphenolic pigments that give turmeric its bright orange-yellow color. Curcumin is the principal curcuminoid in turmeric and is considered the most biologically active.†
Because curcumin is not easily absorbed, many turmeric supplements are not very bioactive in the body. The poor bioavailability is related to curcumin’s low solubility in water. The curcumin that is absorbed is quickly conjugated with either sulfate or glucuronide. This renders the curcuminoids useless to your cells.†
Optimal Liposomal Curcumin solves the issue of low absorption via two strategies: liposomes and resveratrol.†
Liposomes are tiny phospholipid vesicles that mimic our own cell membranes. Because curcuminoids are lipophilic (they attach to fats), you can increase their absorption and bioavailability by taking them with fats. The phospholipid complex in Optimal Liposomal Curcumin provides a fatty base for curcuminoids to bind.†
In addition, the liposomes shield curcumin from digestive processes and from being metabolized by sulfation or glucuronidation. It can then be absorbed by cells fully intact.†
Liposomal curcumin greatly enhances:†
- Bioavailability
- Protection
- Absorption
- Cellular update
- Utilization
Many liposomal formulations are derived from soy. Optimal Liposomal Curcumin utilizes a soy-free liposomal delivery system. This protects fragile curcumin through your GI tract to enhance delivery to your cells.†
Optimal Liposomal Curcumin features a synergistic blend of curcumin and resveratrol, a well-researched phenolic compound. When given together, resveratrol seems to slow the glucuronidation of curcuminoids, allowing for more of these helpful compounds to reach their target cells to carry out beneficial properties.†
Resveratrol also plays a role in regulating NF𝜅𝛃 function as well as another transcription factor called PGC1α. This powerful gene modulator helps read genes that regulate metabolism and mitochondrial function. In fact, PGC1α stimulation in cells has been shown to encourage mitochondrial biogenesis. By supporting cells to create more mitochondria, you have more energy powerhouses to encourage healthy metabolism.†
Resveratrol has also been shown to slow some of the enzymes that conjugate curcuminoids. By combining the two, more curcuminoids can reach cells in their functional form.†
Like curcumin, resveratrol is not easily absorbed into the body. Often, really high levels are needed to make a difference. Optimal Liposomal Curcumin surrounds both compounds with a liposomal sphere to protect them from stomach acid, digestive enzymes, intestinal microbes, and oxidative damage. This greatly enhances the absorption and delivery of curcumin and resveratrol to your cells, where you need it most.†
Optimal Liposomal Curcumin provides 250 mg of curcuminoids with 75 mg of resveratrol per serving. For curcumin without resveratrol in capsule form, try our Optimal Curcumin.