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ProBiota HistaminX


Low Histamine Probiotics

  • Histamine-friendly probiotic formulated without strains known to produce high levels of histamine
  • Supports microbiome balance and a healthy gut response to ingested histamine
  • Supports the health of your immune system and skin

Third Party Tested

Free Shipping

60-day Return Policy

High End Ingredients

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This really seems to help with my histamine intolerance!

I'm several months into a histamine lowering regimen that includes these probiotics and a very low histamine diet. These have really helped to 'empty the bucket' of histamines I've been dealing with and my symptoms are much more manageable. Thank you! ~Sierra

Does your histamine response get worse when using most probiotics?

Do you have histamine concerns such as headaches, intestinal upset, skin issues, or heart palpitations? Are you looking to support your gut microbiome, but aren’t sure where to start?

ProBiota HistaminX is a unique probiotic supplement designed specifically for those sensitive to histamine.

If you relate to one or or more of the following statements, then Probiota HistaminX may be helpful for you in supporting a healthy gut and histamine levels:

  • I experience histamine related symptoms when I take probiotics, especially ones that contain Streptococcus, L. fermentum, L. casei, L. bulgaricus
  • I would like to support my gut health
  • I have histamine intolerance
  • I currently take DAO enzyme but would like additional histamine support
  • I follow a low histamine diet but still experience symptoms of histamine intolerance
  • I have been told that I have a leaky gut
  • My bowel movements are often loose or just inconsistent
  • I have an imbalance of my gut microbiome
  • I have a dirty DAO gene

Most probiotic strains naturally produce histamine in the body. This can cause adverse reactions in people who struggle with excess histamine or histamine intolerance.

Your gut health is a key factor in maintaining healthy histamine levels throughout your body. With nearly 400 5-star reviews, ProBiota HistaminX is a best-seller for good reason. Thousands of people worldwide use it every day to support healthy gut bacteria and histamine metabolism. Whether or not you struggle with histamine, ProBiota HistaminX was designed to support your daily gut health in only one capsule per day.

Key Ingredients

Inside the Uncompromising Quality of Our Ingredients

  • Histamine-friendly probiotics
    Support healthy histamine levels in your body, specifically excluding strains known to produce histamine
  • Acid-resistant Capsule
    Protects probiotics strains from stomach acid for targeted delivery to the gut

Suggested Use

As needed, take 1 capsule after dinner. Capsule may be opened and contents emptied into a bite of food or drink. Use as directed by your healthcare professional.


Consult with your healthcare professional prior to use. Do not use if inner tamper seal is damaged.

Suitable for


Delivery Method


How to Store

Keep closed in a cool, dry place out of reach by children.

  • No Artificial Preservatives
  • No Artificial Flavors
  • No Artificial Colors
  • Wheat-Free
  • Tree-Nut-Free
  • Shellfish-Free
  • Soy-Free
  • Peanut-Free
  • GMO-Free
  • Gluten-Free
  • Fish-Free
  • Egg-Free
  • Dairy-Free
  • Corn-Free

What our customers say

Real reviews from real customers.

Rated 4.8 out of 5 stars
Based on 1,183 reviews
Total 5 star reviews: 1.1k Total 4 star reviews: 87 Total 3 star reviews: 11 Total 2 star reviews: 8 Total 1 star reviews: 17
96%would recommend this product
1,183 reviews
  • S
    Verified Reviewer
    I recommend this product
    Rated 5 out of 5 stars
    Histamine nutrients

    Do you still sell histamine nutrients?I think I'm deficient but not sure on which amd believe this is why I can't get rid of excess histamine ?many thanks

  • J
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Great Probiotic

    I have trouble taking most probiotics due to histamine sensitivity--except this one! My son takes it also with no issues.

  • L
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    No histamine reaction

    For year sI tried probiotics and kept having histamine reactions. The reaction was misdiagnosed as nerve neuropathy, even though I wasn’t diabetic. With much diligence, trial and error, and process of illumination, I found out it was the probiotic. My first clue was that every time I ate yogurt I would have the same reaction.

    After taking histaminX for over a year my problem has been solved and there are no reactions.

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