StrateGene™

List price: $

$45.00 You save: $$$ (%)

Key Benefits and Actions*

Overlay your SNPs or that of your patient’s SNPs onto the Pathway Planner using StrateGene Strategic Genetic Analysis! After two years of digging through research, Dr. Lynch’s research team has identified key SNPs which are clinically relevant – and more importantly – which ones are not.

How To Use - Click here.



What does StrateGene provide?

  • SNPs identified by AncestryDNA (Version 2 only) OR 23andMe.
  • Well-researched SNPs.
  • Factors which influence each SNP.
  • Description of each SNP.
  • Kinetic variation.
  • Associated conditions and symptoms according to research.


StrateGene has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease.

Videos


With StrateGene™ you can quickly learn about potential issues by overlaying your SNPs or those of your patients onto the Pathway Planners covering the important folate, methionine, transsulfuration, biopterin, and histamine pathways.

What is StrateGene™?

StrateGene™ is a genetic reporting tool that uses AncestryDNA (Version 2 only) OR 23andMe data.

By limiting report data to well-researched SNPs, a qualified health care practitioner is able to formulate a targeted testing and treatment plan – faster.

For the last two years, Dr. Lynch and his research team have analyzed SNP after SNP. In order for the SNP to meet inclusion criteria, it had to meet these standards:
  • The SNP is found in AncestryDNA V2 or 23andMe (current or past chips).
  • The SNP is found in a gene that belongs to a biochemical pathway that is covered by StrateGene™.
  • There is a critical mass of published research related to the SNP.
  • The SNP has potential clinical implications as determined by published research.

What genetic tests can be used with StrateGene™?

  • AncestryDNA: StrateGene™ only works with AncestryDNA tests purchased AFTER MAY 2016 (Version 2 only). Not compatible with earlier test data.
  • 23andMe: StrateGene™ works with all (past and current) 23andMe chips. However, if you purchased 23andMe after August 2017, some SNPs that were available with previous chips will be missing from your report.

Genes Evaluated by StrateGene™

The SNPs analyzed and reported by Ancestry are different from those available from the most up-to-date version of 23andMe.

Key differences:

  • You get MAOA, MAOB, and DAO included with Ancestry V2 (not included on 23andMe-based StrateGene™ reports). These are "Super Seven" Genes!
  • You get a total of 2 more RSID#'s analyzed with Ancestry V2 than with 23andMe.

See below for more detail on which polymorphisms are analyzed by each option.

SNP Comparison

SNP RSID 23andMe (prior to August 2017) 23andMe V5 (after August 2017) AncestryDNA V2 (after May 2016)
CORE SNPs
SLC19a1 rs1051266
MTHFD1 rs2236225
MTHFR rs1801131
MTHFR rs1801133
MTRR rs1801394
MTRR rs1532268
MAT1A rs72558181
CBS rs28934891
CBS rs4920037
CBS rs234706
SOD2 rs4880
SOD3 rs1799895
GSTP1 rs1695
GSTP1 rs1138272
G6PD rs1050828
G6PD rs1050829
G6PD rs5030868
GPX1 rs1050450
NOS3/eNOS rs1800783
NOS3/eNOS rs1800779
SULT1A1 i6018900
MAOA rs6323
MAOA rs1137070
MAOB rs1799836
COMT rs4680
COMT rs4633
AOC1 (DAO) rs10156191
NAT2
BONUS SNPs
BCO1 rs12934922
BCO1 rs7501331
BCO1 (PKD1L2) rs6420424
BCO1 rs11645428
BCO1 rs6564851
FUT2 rs601338
NQO1 rs1800566
HFE rs1800562
HFE rs1799945
HFE i3002468/rs1800730
PEMT rs7946
FADS1 (MYRF) rs174537
FADS1 rs174548
FADS2 rs1535
TNF-alpha rs1800629
LRRK2 rs34637584
VDR rs2228570
VDR rs731236
VDR rs1544410
APOE rs7412
APOE rs429358*

*Ancestry has pulled APOE RS# 429358 from their reporting. There is some speculation with how AncestryDNA reported on APOE SNP RS# 429358 as stated here: https://www.snpedia.com/index.php/Gs246  

If you would like to get your reporting on this genotype, 23andMe raw data may be used instead. 

 

Should I order 23andMe still?

AncestryDNA test is recommended. If you have not yet run 23andMe, you may still benefit from it if you are ok with not having the above SNPs in your results. It is still a good value for $99. If you want your StrateGene™ results to include MAOA, MAOB, or DAO, consider AncestryDNA V2 instead.

How is StrateGene™ laid out?

Section 1 – Overview tables of known SNPs with gene, rsid, variant name, risk allele, and genotype. In addition “GSTT1 deletion”, if detected, plus the predicted NAT2 acetylator phenotype.

Section 2 – Results for each pathway with description, SNPs overlaid onto Pathway Planners, and details on SNPs found. The gene and SNP details include influencing factors on genes, SNP kinetic impact, and potential associated symptoms and conditions.

Section 3 – A discussion of “bonus SNPs”. These are SNPs for which there is not yet Pathway Planner graphics available, but which the research team wanted to include for added value.

Who may order StrateGene™?

Both wholesale and retail customers may order StrateGene™ – Strategic Genetic Analysis.

If you are a patient, we recommend consulting with a healthcare professional to receive advice on how to use the information in the StrateGene™ report.

Key Resources to Help You Use StrateGene™

  • How to Use StrateGene™ – a key video to watch first.
  • Private StrateGene™ Facebook Group – support yourself by interacting with other StrateGene™ users. Dr Lynch will be answering questions here via Facebook Live video twice a month!
  • How to Treat SNPs – a key video on how to approach SNPs.
  • What is Methylation? – a key pathway in the human body which does a ton of stuff.
  • Practical Application of Methylation and Epigenetics – this conference presentation by Dr Lynch received rare 100% approval rating. This combined with your StrateGene™ report will take you to the next level.
  • Directory – find a health professional near you who understands how to use StrateGene™. Health professionals here have received training from Dr Lynch in methylation, genetic polymorphisms and epigenetics.
Learning Center Find product FAQ and more! Click here.
Return Policy StrateGene purchases are not eligible for returns or refunds.

Customer Reviews

Based on 106 reviews Write a review