MTHFR Test - MTHFR Genotyping Laboratory Test - SpectraCell

SCELL-MTHFR-TEST

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Fulfillment:  Orders placed by 12 pm Pacific Standard Time ship the same day during normal business hours Monday-Friday. Orders placed on Saturday and Sunday or during holidays will ship the following business day. Please note that shipping during peak times may be delayed and we are not responsible for delivery delays due to adverse weather conditions. We ship USPS First Class Mail or Priority Mail on most shipments unless you choose a different method.

Continental US, APO, Hawaii, and Puerto Rico Shipping Policy:

Free Shipping: Seeking Health customers are eligible for free shipping on orders over $50.00 and wholesale orders over $1,000.00 to the 48 contiguous states. Priority shipping will be used to ship orders under 50lbs. Ground services will be used to ship orders over 50lbs. 

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We quickly ship international orders to just about anywhere in the world via United States Postal Service, Federal Express and MyUs. Delivery time depends on shipping address. It is the customers responsibility to contact local customs, the courier office regarding any additional and applicable customs, duties, or VAT charges. If an order is refused/returned, we will credit for the cost of the product only, not the shipping charges. Please note, MyUs is a mail forwarding service. You will need to register at MyUs.com to use this service.  

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How do I subscribe? There are 2 convenient ways to subscribe according to your preference:

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       2. Call 800-547-9812 to have a support representative begin the subscription process for you.

F.A.Q's

How will I know that my autoship was processed? You will receive an order confirmation via email.

How do I pay? When its time to refill your order, we'll automatically bill the payment method used to subscribe to the product.

How do I stop autoship? You can manage your subscriptions by going to My Account, then to My Subcriptions.

Is there a charge for this service? Our autoship program is free of charge. You'll only be billed for the product plus shipping.

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Your information, whether public or private, will not be sold, exchanged, transferred, or given to any other company for any reason whatsoever, without your consent, other than for the express purpose of delivering the purchased product or service requested.


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The email address you provide for order processing, may be used to send you information and updates pertaining to your order, in addition to receiving occasional company news, updates, related product or service information, etc.

Note: If at any time you would like to unsubscribe from receiving future emails, we include detailed unsubscribe instructions at the bottom of each email.


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We implement a variety of security measures to maintain the safety of your personal information when you place an order or enter, submit, or access your personal information.

We offer the use of a secure server. All supplied sensitive/credit information is transmitted via Secure Socket Layer (SSL) technology and then encrypted into our Payment gateway providers database only to be accessible by those authorized with special access rights to such systems, and are required to keep the information confidential.

After a transaction, your private information (credit cards, social security numbers, financials, etc.) will not be stored on our servers.

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Yes (Cookies are small files that a site or its service provider transfers to your computers hard drive through your Web browser (if you allow) that enables the sites or service providers systems to recognize your browser and capture and remember certain information

We use cookies to help us remember and process the items in your shopping cart, understand and save your preferences for future visits and compile aggregate data about site traffic and site interaction so that we can offer better site experiences and tools in the future. We may contract with third-party service providers to assist us in better understanding our site visitors. These service providers are not permitted to use the information collected on our behalf except to help us conduct and improve our business.

If you prefer, you can choose to have your computer warn you each time a cookie is being sent, or you can choose to turn off all cookies via your browser settings. Like most websites, if you turn your cookies off, some of our services may not function properly. However, you can still place orders over the telephone or by contacting customer service.

Do we disclose any information to outside parties?

We do not sell, trade, or otherwise transfer to outside parties your personally identifiable information. This does not include trusted third parties who assist us in operating our website, conducting our business, or servicing you, so long as those parties agree to keep this information confidential. We may also release your information when we believe release is appropriate to comply with the law, enforce our site policies, or protect ours or others rights, property, or safety. However, non-personally identifiable visitor information may be provided to other parties for marketing, advertising, or other uses.


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We are in compliance with the requirements of COPPA (Childrens Online Privacy Protection Act), we do not collect any information from anyone under 13 years of age. Our website, products and services are all directed to people who are at least 13 years old or older.

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Under the Fair Credit Billing Act, your bank cannot hold you liable for more than 50.00 of fraudulent charges. If your bank does hold you liable for any of this 50.00, we will cover the entire liability for you, up to the full 50.00. We will only cover this liability if the unauthorized use of your credit card resulted through no fault of your own from purchases made while using the secure server. In the event of unauthorized use of your credit card, you must notify your credit card provider in accordance with its reporting rules and procedures.

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Changes to our Privacy Policy

If we decide to change our privacy policy, we will post those changes on this page, and/or update the Privacy Policy modification date below.

This policy was last modified on 4/10/2014

Contacting Us

If there are any questions regarding this privacy policy you may contact us using the information below.

www.SeekingHealth.com
1708 Kentucky Street
Bellingham, WA 98229
United States
customer@seekinghealth.com
800-547-9812

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Returns & Replacements

Effective August 2013

Your complete satisfaction is our ultimate goal. You may return any item shipped by SeekingHealth.com, as long as the item is being returned within 60 days of receipt. 

Please note, Seeking Health cannot be held liable for negative side effects or adverse reactions you believe are the result of a product. We recommend that you seek the guidance of a healthcare professional if you have questions, before purchasing any product.

Return postage is the responsibility of the buyer. If the package is lost, Seeking Health is not responsible for them. We recommend you insure the return package and obtain a tracking number. Before you return the product to us, you will need to obtain a Return Merchandise Authorization number from a Customer Care Specialist. Please call us for your RMA number -  800-547-9812. Please have your order number and the name(s) of the product(s) you are returning ready when you call.

Damaged, Defective, or Incorrect Items

We are committed to providing the highest level of service possible. If there is a problem with your order, please contact Customer Care immediately.  Provide us with as much information as you can about the problem, including your order number, name of the affected items and if you would like a return or a replacement. If you received the wrong product we will ship the correct item at no additional cost to you. If an item arrived damaged, we will replace it at no additional cost to you. If you wish to exchange a product, you will need to return the unopened product for a refund and place a new order for the product you would like in exchange.  

Please do not discard any items unless you have been directed to do so by a Customer Care Specialist.

Once we receive your return, we will issue a credit or refund within 7 business days and send you an e-mail confirmation. Please bear in mind that it can take several days for the transaction to appear on your account, depending on your financial institution.

 

 

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Ordering

We maintain 99% of offered products in our own warehouse. This allows us to control inventory and quickly get product to our customers. Many companies hire fulfillment centers to store and ship product. We have researched this option and found it unreliable and too slow.

  • All Items in stock unless marked otherwise on our site
  • Out of Stock items will display a link stating that the item is Out of Stock. A couple options exist here:
    1. You may still purchase this item but do understand that there may be a delay of 7 to 14 days. We will send you an email when we are processing your order to ship.
    2. You may click the Notify Me When In Stock link and we will automatically send you an email when that item arrives in our warehouse.

 

 

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Viewing Orders

To View orders login to the "My Account" section. From here you can view your recent and past orders as well as get tracking information. If you do not find tracking in your order after 48 hours, we recommend you call us or e-mail to inquire.
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Quick Overview

MTHFR Test by SpectraCell provides critical information relating the the most common MTHFR mutations: C677T and A1298C and the variants thereof. This MTHFR Test is critical to order should someone have cardiovascular risk, autism, chemical sensitivity, cancer risk, miscarriages or your doctor recommends it.* MTHFR Test is inexpensive compared to the lifelong benefits it can provide you. Insurance is NOT accepted for this test.

This test is available to residents in the United States, Canada and Puerto Rico only. Due to certain regulations this test is not available to Maryland, Massachusetts, New Jersey, New York, and Rhode Island residents.

Results: Results can take up to 4 weeks to receive from the lab and are emailed by Dr. Lynch every Monday along with brief interpretations and suggestions. All test results are sent to us confidentially and are emailed to the individual who ordered it. If exceptions occur, we must be notified directly via email customer@seekinghealth.com.

Product Description

MTHFR is an enzyme responsible for converting 5,10-methylenetetrahydrofolate to the product 5-methyltetrahydrofolate - it is involved in the metabolism of folate and homocysteine. The product of the reaction catalyzed by MTHFR converts homocysteine (a potentially toxic amino acid) to methionine (a useful and necessary amino acid).*

Why is MTHFR Genotyping Important?

  • Certain mutations in the gene coding for MTHFR produce an enzyme that has reduced activity.
  • Reduced activity can lead to elevated levels of homocysteine (a.k.a. hyperhomocysteinemia), especially when folate levels are low.*
  • High homocysteine (>13umol/L) may double the risk of developing illness or complications.*
  • MTHFR genotyping may provide information about potential causes of elevated homocysteine and approaches for addressing it.*
  • Based on MTHFR and homocysteine results, physicians can develop dietary and medical recommendations - increased intake of folate alone or in combination with vitamins B6 and B12 are recommended.*
  • Based on results, recommendations for methotrexate dosage may be adjusted.*

Risks Associated with MTHFR Variants/High Homocysteine:

  • Cardiovascular Disease
  • Cerebral Vascular Disease (Stroke)
  • Venous and Arterial Thrombosis
  • Methotrexate Toxicity for Cancer Therapy

Who Should be Tested?

  • Those with high homocysteine levels.*
  • Those who have a familial history of cardiovascular disease, stroke or thrombosis.*
  • Those who are candidates for long-term methotrexate therapy.*

Collection/Packaging Instructions:

NO FASTING REQUIRED

Whole blood is required.

Collect one purple top (EDTA) tube.

Do no centrifuge or freeze

 

Shipping Instructions:

Ship in the LPP kit or the micronutrient test kit provided

 

DO NOT PLACE THE SHIPMENT IN A DROP BOX

DO NOT USE THE AUTOMATED SYSTEM WHEN CALLING FOR A PICK UP.  SPEAK WITH A CUSTOMER SERVICE REPRESENTATIVE.

It is very important to receive the specimens the day after collection

Call FedEx for courier pickup ASAP at 800-463-3339, but no later than 3:00PM, Monday-Friday

Give your address as the pickup location

THE SPECTRACELL LABORATORY IS OPEN ON SATURDAYS TO RECEIVE SPECIMENS COLLECTED ON FRIDAYS

Results: Results can take up to 4 weeks to receive from the lab and are emailed by Dr. Lynch every Monday along with brief interpretations and suggestions. All test results are sent to us confidentially and are emailed to the individual who ordered it. If exceptions occur, we must be notified directly via email customer@seekinghealth.com.

SpectraCell Laboratories now offers a test for the MTHFR gene, which is associated with elevated levels of the toxic amino acid homocysteine.  Individuals with specific mutations of the MTHFR (methylenetetrahydrofolate reductase) gene may have a higher risk for cardiovascular disfunction due to high levels of homocysteine in their blood.* 

MTHFR is an enzyme responsible for the proper metabolism of the harmful amino acid homocysteine into the benign amino acid methionine.   This metabolic process also needs folate and B vitamins to function properly. In people who carry the dangerous version of this gene, the enzyme does not work efficiently and higher than normal amounts of folate and vitamin B12 and B6 are used up in the process.*  

Consequently, these individuals may have a risk for developing cardiovascular disease since homocysteine acts like an abrasive to our blood vessels causing damage to the vascular wall when levels are chronically elevated (above 13umol/L).* 

Testing for mutations in the MTHFR gene is useful in identifying a cause for persistent hyperhomocysteinemia.*  For example, people with the dangerous version of the gene may tend to develop deficiencies in folate or vitamin B6 or B12, which can be treated.*   

Approximately 55% of the population carries one or more of the high risk variants within the MTHFR gene.*  About 10% of the population carries two copies of one of the high risk genes.  Specifically, low folate status affects those with the 677TT genotype much more than those with either the 677CC/CT genotypes, but these individuals also have a decreased risk for certain cancers.*  

SpectraCell identifies the two most common mutations that can occur in the MTHFR gene: one is located at position 677, the other at position 1298 within the gene.  Therefore, three possible genotypes exist for each of the locations on the gene: 677CC, 677CT, 677TT and 1298AA, 1298AC, 1298CC.   The highest risk for hyperhomocysteinemia is seen in people with the 677TT variant combined with 1298AC or 1298CC.* The frequency of the A1298C mutation is reported to be as high as 30% in the general population.* 

“One of the biggest benefits of this test is to determine the appropriate level of folate for healthy cardiovascular disease function.* Elevated homocysteine is quite common (over 10% of the world population), so there are a lot of people who might benefit from MTHFR testing.” states Dr. Jonathan 

Stein, PhD and Director of Science and Research at SpectraCell Laboratories.  “When it comes to supplementation, more is not always better.  It’s important to know whether or not a specific therapeutic dosage will work, and MTHFR testing helps a clinician know which dosage is optimal.*” 

SpectraCell uses PCR (polymerase chain reaction) technology to measure the MTHFR gene.  Since this is a genetic test and therefore results do not vary over time, it only needs to be done once per lifetime.  However, MTHFR genotyping is best when used in conjunction with additional genetic and lipid profile testing, and especially with micronutrient testing for folate and other B vitamins.  A simple non-fasting blood draw is all that is required.  The cash price of the MTHFR test is $195, although it is typically covered by insurance.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Additional Information

Product Name MTHFR Test - MTHFR Genotyping Laboratory Test - SpectraCell
MPN SCELL-MTHFR-TEST
Return Policy This test is pre-paid. You may request a full refund if the test kit has not been used.
SKU SCELL-MTHFR-TEST
Does not contain Gluten, Dairy, Egg, Soy, Fish, Shellfish, Nuts, Corn, GMO, Prebiotics
Retail Price $0.00

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