Dirty Genes® - MTHFR Supplements
If you have an MTHFR gene SNP, you need supplementation that is bioavailable and doesn’t slow down your methylation processes. MTHFR (short for methylenetetrahydrofolate reductase) produces an enzyme that helps regulate how well your DNA methylation cycle works. Polymorphisms mean that MTHFR less efficiently converts folic acid (vitamin B9) and vitamin B12 to active forms.
If you have an MTHFR gene SNP, you need supplementation that is bioavailable and doesn’t slow down your methylation processes. MTHFR (short for methylenetetrahydrofolate reductase) produces an enzyme that helps regulate how well your DNA methylation cycle works. Polymorphisms mean that MTHFR less efficiently converts folic acid (vitamin B9) and vitamin B12 to active forms.
An impaired MTHFR gene can also lead to high homocysteine levels, detoxification challenges, and an increased risk for other problems.
For optimal health, you need bioavailable, methylated nutrients like methylcobalamin (methyl-B12), L-5-MTHF (methylfolate), SAMe, creatine, phosphatidylcholine, and more.
These work to support your body’s methylation processes by reducing the effort needed to activate them.
Your MTHFR gene mutation doesn’t have to confuse you. Get started with MTHFR supplements today. Try Seeking Health’s popular Optimal Multivitamin for comprehensive nutrient support. Or get HomocysteX Plus, which helps to support normal homocysteine conversion. B Complex Plus is a great way to support a healthy MTHFR enzyme.
Not sure where to start with a multivitamin? Use this chart to compare products.

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Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars146 ReviewsFrom $43Key Benefits and Actions† Supports healthy liver metabolism of estrogens Supports detoxification and elimination Supports healthy inflammatory r...
View full details -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Prenatal Essentials MF
5.0Rated 5.0 out of 5 stars101 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full details -
Keep your homocysteine levels in check with the unique formula found in Homocysteine Nutrients!†
Homocysteine Nutrients—Provides the 5 nutrients your body requires for optimal methylation, including folate, methylcobalamin, and adenosylcobalamin, to support normal homocysteine breakdown for heart health support.†
Best SellerHomocysteine Nutrients
4.9Rated 4.9 out of 5 stars261 ReviewsFrom $35Key Benefits and Actions† Supports healthy methylation and homocysteine levels Powerful heart health support Supports healthy cognition and brai...
View full details -
Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!†
Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.†
Best SellerMethyl B12 with L-Methylfolate
4.9Rated 4.9 out of 5 stars762 ReviewsFrom $25Key Benefits and Actions† Active, methylated folate and B12 in a well-absorbed lozenge Potent methylation, homocysteine, and MTHFR support Suppo...
View full details -
Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients - Formerly Histamine Block Plus
4.8Rated 4.8 out of 5 stars277 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
View full details -
Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars190 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
View full details -
Support normal hormone balance, a balanced mood, and healthy energy production with B Complex Plus.†
B Complex Plus—A potent vitamin B complex supplement that provides active forms of the 8 essential B vitamins plus choline for additional methylation support.†
Best SellerB Complex Plus
4.9Rated 4.9 out of 5 stars430 ReviewsFrom $30Key Benefits and Actions† Healthy energy production support Supports normal hormone balance and mood Supports healthy methylation and homocystei...
View full details -
Supports healthy aging, detoxification, immune system, and physical activity with Liposomal Glutathione Plus!†
Liposomal Glutathione Plus—A powerful antioxidant support formula with a liposomal delivery that enhances absorption of the reduced, active form of glutathione and other key nutrients that support glutathione recycling and function.†
Best SellerDiscontinuedLiposomal Glutathione Plus
4.7Rated 4.7 out of 5 stars391 ReviewsFrom $50Key Benefits and Actions† Powerful liposomal glutathione plus nutrients for recycling and utilization Reduced form supports optimal antioxidant ...
View full details -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars114 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details -
Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars338 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
View full details -
Start your day off right by giving your overall health and well-being top priority with Multivitamin One!†
Multivitamin One—A one-day multivitamin containing active forms of your essential daily nutrients in a well-absorbed capsule formulated without vitamin C, magnesium, calcium, or iron to allow customization.†
Best SellerMultivitamin One
4.8Rated 4.8 out of 5 stars372 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring bioavailable nutrients Methyl B12 and methylfolate support optimal methylation Powerf...
View full details -
Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Out of Stock Fish Oil
5.0Rated 5.0 out of 5 stars129 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
View full details -
Get all-in-one health support with the specially formulated blend of nutrients found in Optimal Man™!†
Optimal Man™—A complete multivitamin/multimineral containing supportive herbs with antioxidant properties to support healthy testosterone levels and men’s health and fertility.†
Out of Stock Best SellerOptimal Man™
4.8Rated 4.8 out of 5 stars127 ReviewsFrom $65Key Benefits and Actions† Supports men’s health and male fertility Supports healthy testosterone levels Supports healthy cognition, energy, and ...
View full details -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.8Rated 4.8 out of 5 stars182 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full details -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerProBiota™ HistaminX™
4.8Rated 4.8 out of 5 stars1,302 ReviewsFrom $40Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
View full details -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
SaleBOGOKids Multivitamin Chewable MF
4.5Rated 4.5 out of 5 stars31 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
View full details -
Support healthy detoxification and immune system functioning with easy-to-swallow Glutathione Plus!†
Glutathione Plus—A unique formula with Emothion™ S-Acetyl-L-Glutathione and LifePQQ™ for lung, skin, eye, and immune system support, all in a small taste- and smell-free capsule!†
Best SellerGlutathione Plus
4.9Rated 4.9 out of 5 stars143 ReviewsFrom $65Key Benefits and Actions† Supports healthy lungs, skin, eyes, and immune system Triple glutathione protection due to unique formulation Easy to ...
View full details -
Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars146 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
View full details -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
4.6Rated 4.6 out of 5 stars1,494 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full details -
Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!†
Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).†
Optimal PC
4.9Rated 4.9 out of 5 stars155 ReviewsFrom $45Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...
View full details -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars278 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
View full details -
Support healthy aging, detoxification, immune system health, and physical activity with the antioxidative properties found in Liposomal Glutathione.†
Liposomal Glutathione—Contains 100 mg of reduced glutathione packaged in soy-free liposomes to enhance absorption and delivery in every serving.†
SaleBest SellerBOGOWhile Supplies LastLiposomal Glutathione
4.8Rated 4.8 out of 5 stars409 ReviewsFrom $50Key Benefits and Actions† Powerful, well-absorbed, liposomal glutathione Reduced form promotes superior antioxidant activity Supports healthy ...
View full details -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Out of Stock Optimal Focus
4.7Rated 4.7 out of 5 stars118 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
View full details -
Promote the healthy development of your baby’s brain, spinal cord, and immune system while supporting your pregnancy health with Prenatal Essentials!†
Prenatal Essentials—Contains only the essential nutrients you need in superior and bioavailable forms, including folinic acid, bioactive B12, and chelated minerals for targeted pregnancy support.†
Best SellerPrenatal Essentials
4.8Rated 4.8 out of 5 stars442 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your prenatal vitamin essentials Bioavailable B12 and folate support healthy methylati...
View full details
-
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars146 ReviewsFrom $43Key Benefits and Actions† Supports healthy liver metabolism of estrogens Supports detoxification and elimination Supports healthy inflammatory r...
View full details -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Prenatal Essentials MF
5.0Rated 5.0 out of 5 stars101 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full details -
Keep your homocysteine levels in check with the unique formula found in Homocysteine Nutrients!†
Homocysteine Nutrients—Provides the 5 nutrients your body requires for optimal methylation, including folate, methylcobalamin, and adenosylcobalamin, to support normal homocysteine breakdown for heart health support.†
Best SellerHomocysteine Nutrients
4.9Rated 4.9 out of 5 stars261 ReviewsFrom $35Key Benefits and Actions† Supports healthy methylation and homocysteine levels Powerful heart health support Supports healthy cognition and brai...
View full details -
Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!†
Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.†
Best SellerMethyl B12 with L-Methylfolate
4.9Rated 4.9 out of 5 stars762 ReviewsFrom $25Key Benefits and Actions† Active, methylated folate and B12 in a well-absorbed lozenge Potent methylation, homocysteine, and MTHFR support Suppo...
View full details -
Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients - Formerly Histamine Block Plus
4.8Rated 4.8 out of 5 stars277 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
View full details -
Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars190 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
View full details -
Support normal hormone balance, a balanced mood, and healthy energy production with B Complex Plus.†
B Complex Plus—A potent vitamin B complex supplement that provides active forms of the 8 essential B vitamins plus choline for additional methylation support.†
Best SellerB Complex Plus
4.9Rated 4.9 out of 5 stars430 ReviewsFrom $30Key Benefits and Actions† Healthy energy production support Supports normal hormone balance and mood Supports healthy methylation and homocystei...
View full details -
Supports healthy aging, detoxification, immune system, and physical activity with Liposomal Glutathione Plus!†
Liposomal Glutathione Plus—A powerful antioxidant support formula with a liposomal delivery that enhances absorption of the reduced, active form of glutathione and other key nutrients that support glutathione recycling and function.†
Best SellerDiscontinuedLiposomal Glutathione Plus
4.7Rated 4.7 out of 5 stars391 ReviewsFrom $50Key Benefits and Actions† Powerful liposomal glutathione plus nutrients for recycling and utilization Reduced form supports optimal antioxidant ...
View full details -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars114 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details -
Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars338 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
View full details -
Start your day off right by giving your overall health and well-being top priority with Multivitamin One!†
Multivitamin One—A one-day multivitamin containing active forms of your essential daily nutrients in a well-absorbed capsule formulated without vitamin C, magnesium, calcium, or iron to allow customization.†
Best SellerMultivitamin One
4.8Rated 4.8 out of 5 stars372 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring bioavailable nutrients Methyl B12 and methylfolate support optimal methylation Powerf...
View full details -
Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Out of Stock Fish Oil
5.0Rated 5.0 out of 5 stars129 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
View full details -
Get all-in-one health support with the specially formulated blend of nutrients found in Optimal Man™!†
Optimal Man™—A complete multivitamin/multimineral containing supportive herbs with antioxidant properties to support healthy testosterone levels and men’s health and fertility.†
Out of Stock Best SellerOptimal Man™
4.8Rated 4.8 out of 5 stars127 ReviewsFrom $65Key Benefits and Actions† Supports men’s health and male fertility Supports healthy testosterone levels Supports healthy cognition, energy, and ...
View full details -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.8Rated 4.8 out of 5 stars182 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full details -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerProBiota™ HistaminX™
4.8Rated 4.8 out of 5 stars1,302 ReviewsFrom $40Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
View full details -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
SaleBOGOKids Multivitamin Chewable MF
4.5Rated 4.5 out of 5 stars31 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
View full details -
Support healthy detoxification and immune system functioning with easy-to-swallow Glutathione Plus!†
Glutathione Plus—A unique formula with Emothion™ S-Acetyl-L-Glutathione and LifePQQ™ for lung, skin, eye, and immune system support, all in a small taste- and smell-free capsule!†
Best SellerGlutathione Plus
4.9Rated 4.9 out of 5 stars143 ReviewsFrom $65Key Benefits and Actions† Supports healthy lungs, skin, eyes, and immune system Triple glutathione protection due to unique formulation Easy to ...
View full details -
Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars146 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
View full details -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
4.6Rated 4.6 out of 5 stars1,494 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full details -
Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!†
Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).†
Optimal PC
4.9Rated 4.9 out of 5 stars155 ReviewsFrom $45Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...
View full details -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars278 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
View full details -
Support healthy aging, detoxification, immune system health, and physical activity with the antioxidative properties found in Liposomal Glutathione.†
Liposomal Glutathione—Contains 100 mg of reduced glutathione packaged in soy-free liposomes to enhance absorption and delivery in every serving.†
SaleBest SellerBOGOWhile Supplies LastLiposomal Glutathione
4.8Rated 4.8 out of 5 stars409 ReviewsFrom $50Key Benefits and Actions† Powerful, well-absorbed, liposomal glutathione Reduced form promotes superior antioxidant activity Supports healthy ...
View full details -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Out of Stock Optimal Focus
4.7Rated 4.7 out of 5 stars118 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
View full details -
Promote the healthy development of your baby’s brain, spinal cord, and immune system while supporting your pregnancy health with Prenatal Essentials!†
Prenatal Essentials—Contains only the essential nutrients you need in superior and bioavailable forms, including folinic acid, bioactive B12, and chelated minerals for targeted pregnancy support.†
Best SellerPrenatal Essentials
4.8Rated 4.8 out of 5 stars442 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your prenatal vitamin essentials Bioavailable B12 and folate support healthy methylati...
View full details
-
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars146 ReviewsFrom $43Key Benefits and Actions† Supports healthy liver metabolism of estrogens Supports detoxification and elimination Supports healthy inflammatory r...
View full details -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Prenatal Essentials MF
5.0Rated 5.0 out of 5 stars101 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full details -
Keep your homocysteine levels in check with the unique formula found in Homocysteine Nutrients!†
Homocysteine Nutrients—Provides the 5 nutrients your body requires for optimal methylation, including folate, methylcobalamin, and adenosylcobalamin, to support normal homocysteine breakdown for heart health support.†
Best SellerHomocysteine Nutrients
4.9Rated 4.9 out of 5 stars261 ReviewsFrom $35Key Benefits and Actions† Supports healthy methylation and homocysteine levels Powerful heart health support Supports healthy cognition and brai...
View full details -
Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!†
Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.†
Best SellerMethyl B12 with L-Methylfolate
4.9Rated 4.9 out of 5 stars762 ReviewsFrom $25Key Benefits and Actions† Active, methylated folate and B12 in a well-absorbed lozenge Potent methylation, homocysteine, and MTHFR support Suppo...
View full details -
Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients - Formerly Histamine Block Plus
4.8Rated 4.8 out of 5 stars277 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
View full details -
Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars190 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
View full details -
Support normal hormone balance, a balanced mood, and healthy energy production with B Complex Plus.†
B Complex Plus—A potent vitamin B complex supplement that provides active forms of the 8 essential B vitamins plus choline for additional methylation support.†
Best SellerB Complex Plus
4.9Rated 4.9 out of 5 stars430 ReviewsFrom $30Key Benefits and Actions† Healthy energy production support Supports normal hormone balance and mood Supports healthy methylation and homocystei...
View full details -
Supports healthy aging, detoxification, immune system, and physical activity with Liposomal Glutathione Plus!†
Liposomal Glutathione Plus—A powerful antioxidant support formula with a liposomal delivery that enhances absorption of the reduced, active form of glutathione and other key nutrients that support glutathione recycling and function.†
Best SellerDiscontinuedLiposomal Glutathione Plus
4.7Rated 4.7 out of 5 stars391 ReviewsFrom $50Key Benefits and Actions† Powerful liposomal glutathione plus nutrients for recycling and utilization Reduced form supports optimal antioxidant ...
View full details -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars114 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details -
Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars338 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
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Start your day off right by giving your overall health and well-being top priority with Multivitamin One!†
Multivitamin One—A one-day multivitamin containing active forms of your essential daily nutrients in a well-absorbed capsule formulated without vitamin C, magnesium, calcium, or iron to allow customization.†
Best SellerMultivitamin One
4.8Rated 4.8 out of 5 stars372 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring bioavailable nutrients Methyl B12 and methylfolate support optimal methylation Powerf...
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Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Out of Stock Fish Oil
5.0Rated 5.0 out of 5 stars129 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
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Get all-in-one health support with the specially formulated blend of nutrients found in Optimal Man™!†
Optimal Man™—A complete multivitamin/multimineral containing supportive herbs with antioxidant properties to support healthy testosterone levels and men’s health and fertility.†
Out of Stock Best SellerOptimal Man™
4.8Rated 4.8 out of 5 stars127 ReviewsFrom $65Key Benefits and Actions† Supports men’s health and male fertility Supports healthy testosterone levels Supports healthy cognition, energy, and ...
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Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.8Rated 4.8 out of 5 stars182 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
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Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerProBiota™ HistaminX™
4.8Rated 4.8 out of 5 stars1,302 ReviewsFrom $40Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
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Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
SaleBOGOKids Multivitamin Chewable MF
4.5Rated 4.5 out of 5 stars31 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
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Support healthy detoxification and immune system functioning with easy-to-swallow Glutathione Plus!†
Glutathione Plus—A unique formula with Emothion™ S-Acetyl-L-Glutathione and LifePQQ™ for lung, skin, eye, and immune system support, all in a small taste- and smell-free capsule!†
Best SellerGlutathione Plus
4.9Rated 4.9 out of 5 stars143 ReviewsFrom $65Key Benefits and Actions† Supports healthy lungs, skin, eyes, and immune system Triple glutathione protection due to unique formulation Easy to ...
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Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars146 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
4.6Rated 4.6 out of 5 stars1,494 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
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Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!†
Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).†
Optimal PC
4.9Rated 4.9 out of 5 stars155 ReviewsFrom $45Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...
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Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars278 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
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Support healthy aging, detoxification, immune system health, and physical activity with the antioxidative properties found in Liposomal Glutathione.†
Liposomal Glutathione—Contains 100 mg of reduced glutathione packaged in soy-free liposomes to enhance absorption and delivery in every serving.†
SaleBest SellerBOGOWhile Supplies LastLiposomal Glutathione
4.8Rated 4.8 out of 5 stars409 ReviewsFrom $50Key Benefits and Actions† Powerful, well-absorbed, liposomal glutathione Reduced form promotes superior antioxidant activity Supports healthy ...
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Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Out of Stock Optimal Focus
4.7Rated 4.7 out of 5 stars118 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
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Promote the healthy development of your baby’s brain, spinal cord, and immune system while supporting your pregnancy health with Prenatal Essentials!†
Prenatal Essentials—Contains only the essential nutrients you need in superior and bioavailable forms, including folinic acid, bioactive B12, and chelated minerals for targeted pregnancy support.†
Best SellerPrenatal Essentials
4.8Rated 4.8 out of 5 stars442 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your prenatal vitamin essentials Bioavailable B12 and folate support healthy methylati...
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Support the healthy conversion of fat into energy with Acetyl-L-Carnitine.†
Acetyl-L-carnitine—A unique, bioavailable amino acid that supports healthy energy production, brain and nervous system function, and fat metabolism.†

Acetyl-L-Carnitine
Key Benefits and Actions† Supports conversion of fat into energy Supports healthy heart, brain, muscle, and sperm function Supports athletic per...
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