Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.

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Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars151 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
View full details -
Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars197 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
View full details -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
SaleBOGOBOGOBrain Nutrients
4.6Rated 4.6 out of 5 stars80 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
View full details -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
4.4Rated 4.4 out of 5 stars36 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
View full details -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars120 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars283 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
View full details -
Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Fish Oil
5.0Rated 5.0 out of 5 stars148 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
View full details -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
4.8Rated 4.8 out of 5 stars205 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full details -
Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients
4.8Rated 4.8 out of 5 stars284 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
View full details -
Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
SaleBOGOBOGODopamine Nutrients
4.6Rated 4.6 out of 5 stars44 ReviewsFrom $46Key Benefits:† Supports healthy mood and motivation Supports healthy learning and memory Supports healthy libido and drive Dopamine Nutrients w...
View full details -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
SaleBOGOBOGOOptimal Focus
4.6Rated 4.6 out of 5 stars123 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
View full details -
Get the upper hand on stress by supporting feelings of calm and mood balance with Phosphatidyl Serine!†
Phosphatidyl Serine—A phospholipid that supports a healthy stress response with 150 mg of non-GMO sunflower-sourced phosphatidylserine per capsule.†
Phosphatidyl Serine
4.8Rated 4.8 out of 5 stars53 ReviewsFrom $45Key Benefits and Actions† Supports healthy concentration and cognition Supports feelings of calm and healthy mood Helps to support a healthy str...
View full details -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerProBiota™ HistaminX™
4.8Rated 4.8 out of 5 stars1,333 ReviewsFrom $40Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
View full details -
Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Best SellerOptimal Magnesium
4.9Rated 4.9 out of 5 stars701 ReviewsFrom $20Key Benefits and Actions† Lysinate, glycinate, and malate forms of magnesium for optimal bioavailability Supports GI comfort, relaxation, and na...
View full details -
Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars349 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
View full details -
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars152 ReviewsFrom $43Key Benefits:† DIM Supplement Supports healthy liver metabolism of estrogens Glutathione added to support healthy estrogen detoxification Support...
View full details -
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
4.9Rated 4.9 out of 5 stars190 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full details -
Customize your vitamin intake to support your specific health needs—especially if you have sensitivities—with Multivitamin One Sensitive!†
Multivitamin One Sensitive—A customizable multivitamin and mineral supplement. It is strategically formulated without certain nutrients to allow for individual serving size customization.†
ImprovedMultivitamin One Sensitive
4.4Rated 4.4 out of 5 stars62 ReviewsFrom $35Key Benefits and Actions† Designed for sensitive individuals One-a-day multivitamin with chelated trace minerals Free from B12, Folate, Copper, ...
View full details -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
4.6Rated 4.6 out of 5 stars1,542 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full details -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.8Rated 4.8 out of 5 stars188 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full details -
Support normal liver and gut detoxification and healthy cholesterol and estrogen levels with Calcium D-Glucarate.†
Calcium D-Glucarate—Contains 250 mg of calcium D-glucarate, a form of glucaric acid that is stabilized with calcium to support your body’s healthy natural detoxification function.†
Calcium D-Glucarate
4.9Rated 4.9 out of 5 stars134 ReviewsFrom $32Key Benefits and Actions† Supports liver & gut detoxification Supports normal estrogen metabolism Supports normal cholesterol levels Who Ne...
View full details
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Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars151 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
View full details -
Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars197 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
View full details -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
SaleBOGOBOGOBrain Nutrients
4.6Rated 4.6 out of 5 stars80 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
View full details -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
4.4Rated 4.4 out of 5 stars36 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
View full details -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars120 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars283 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
View full details -
Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Fish Oil
5.0Rated 5.0 out of 5 stars148 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
View full details -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
4.8Rated 4.8 out of 5 stars205 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full details -
Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients
4.8Rated 4.8 out of 5 stars284 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
View full details -
Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
SaleBOGOBOGODopamine Nutrients
4.6Rated 4.6 out of 5 stars44 ReviewsFrom $46Key Benefits:† Supports healthy mood and motivation Supports healthy learning and memory Supports healthy libido and drive Dopamine Nutrients w...
View full details -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
SaleBOGOBOGOOptimal Focus
4.6Rated 4.6 out of 5 stars123 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
View full details -
Get the upper hand on stress by supporting feelings of calm and mood balance with Phosphatidyl Serine!†
Phosphatidyl Serine—A phospholipid that supports a healthy stress response with 150 mg of non-GMO sunflower-sourced phosphatidylserine per capsule.†
Phosphatidyl Serine
4.8Rated 4.8 out of 5 stars53 ReviewsFrom $45Key Benefits and Actions† Supports healthy concentration and cognition Supports feelings of calm and healthy mood Helps to support a healthy str...
View full details -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerProBiota™ HistaminX™
4.8Rated 4.8 out of 5 stars1,333 ReviewsFrom $40Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
View full details -
Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Best SellerOptimal Magnesium
4.9Rated 4.9 out of 5 stars701 ReviewsFrom $20Key Benefits and Actions† Lysinate, glycinate, and malate forms of magnesium for optimal bioavailability Supports GI comfort, relaxation, and na...
View full details -
Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars349 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
View full details -
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars152 ReviewsFrom $43Key Benefits:† DIM Supplement Supports healthy liver metabolism of estrogens Glutathione added to support healthy estrogen detoxification Support...
View full details -
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
4.9Rated 4.9 out of 5 stars190 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full details -
Customize your vitamin intake to support your specific health needs—especially if you have sensitivities—with Multivitamin One Sensitive!†
Multivitamin One Sensitive—A customizable multivitamin and mineral supplement. It is strategically formulated without certain nutrients to allow for individual serving size customization.†
ImprovedMultivitamin One Sensitive
4.4Rated 4.4 out of 5 stars62 ReviewsFrom $35Key Benefits and Actions† Designed for sensitive individuals One-a-day multivitamin with chelated trace minerals Free from B12, Folate, Copper, ...
View full details -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
4.6Rated 4.6 out of 5 stars1,542 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full details -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.8Rated 4.8 out of 5 stars188 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full details -
Support normal liver and gut detoxification and healthy cholesterol and estrogen levels with Calcium D-Glucarate.†
Calcium D-Glucarate—Contains 250 mg of calcium D-glucarate, a form of glucaric acid that is stabilized with calcium to support your body’s healthy natural detoxification function.†
Calcium D-Glucarate
4.9Rated 4.9 out of 5 stars134 ReviewsFrom $32Key Benefits and Actions† Supports liver & gut detoxification Supports normal estrogen metabolism Supports normal cholesterol levels Who Ne...
View full details
-
Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars151 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
View full details -
Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars197 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
View full details -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
SaleBOGOBOGOBrain Nutrients
4.6Rated 4.6 out of 5 stars80 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
View full details -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
4.4Rated 4.4 out of 5 stars36 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
View full details -
Choose the natural way to support a healthy stress response, cortisol regulation, and feelings of calm with Stress Nutrients!†
Stress Nutrients—A vegan-friendly adrenal support supplement. Nutrients, plant extracts, and herbs synergistically support adrenal health and a normal stress response.†
Stress Nutrients
4.9Rated 4.9 out of 5 stars120 ReviewsFrom $38Key Benefits and Actions† Non-glandular adrenal support supplement Synergistic nutrients and herbs for healthy stress responses Supports healthy...
View full details -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
Multivitamin One MF
4.9Rated 4.9 out of 5 stars283 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
View full details -
Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Fish Oil
5.0Rated 5.0 out of 5 stars148 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
View full details -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
4.8Rated 4.8 out of 5 stars205 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full details -
Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients
4.8Rated 4.8 out of 5 stars284 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
View full details -
Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
SaleBOGOBOGODopamine Nutrients
4.6Rated 4.6 out of 5 stars44 ReviewsFrom $46Key Benefits:† Supports healthy mood and motivation Supports healthy learning and memory Supports healthy libido and drive Dopamine Nutrients w...
View full details -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
SaleBOGOBOGOOptimal Focus
4.6Rated 4.6 out of 5 stars123 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
View full details -
Get the upper hand on stress by supporting feelings of calm and mood balance with Phosphatidyl Serine!†
Phosphatidyl Serine—A phospholipid that supports a healthy stress response with 150 mg of non-GMO sunflower-sourced phosphatidylserine per capsule.†
Phosphatidyl Serine
4.8Rated 4.8 out of 5 stars53 ReviewsFrom $45Key Benefits and Actions† Supports healthy concentration and cognition Supports feelings of calm and healthy mood Helps to support a healthy str...
View full details -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerProBiota™ HistaminX™
4.8Rated 4.8 out of 5 stars1,333 ReviewsFrom $40Key Benefits and Actions† Histamine-friendly probiotic formulated without strains known to produce high levels of histamine Supports microbiome ...
View full details -
Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Best SellerOptimal Magnesium
4.9Rated 4.9 out of 5 stars701 ReviewsFrom $20Key Benefits and Actions† Lysinate, glycinate, and malate forms of magnesium for optimal bioavailability Supports GI comfort, relaxation, and na...
View full details -
Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars349 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
View full details -
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars152 ReviewsFrom $43Key Benefits:† DIM Supplement Supports healthy liver metabolism of estrogens Glutathione added to support healthy estrogen detoxification Support...
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Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
4.9Rated 4.9 out of 5 stars190 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
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Customize your vitamin intake to support your specific health needs—especially if you have sensitivities—with Multivitamin One Sensitive!†
Multivitamin One Sensitive—A customizable multivitamin and mineral supplement. It is strategically formulated without certain nutrients to allow for individual serving size customization.†
ImprovedMultivitamin One Sensitive
4.4Rated 4.4 out of 5 stars62 ReviewsFrom $35Key Benefits and Actions† Designed for sensitive individuals One-a-day multivitamin with chelated trace minerals Free from B12, Folate, Copper, ...
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
4.6Rated 4.6 out of 5 stars1,542 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
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Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.8Rated 4.8 out of 5 stars188 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
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Support normal liver and gut detoxification and healthy cholesterol and estrogen levels with Calcium D-Glucarate.†
Calcium D-Glucarate—Contains 250 mg of calcium D-glucarate, a form of glucaric acid that is stabilized with calcium to support your body’s healthy natural detoxification function.†
Calcium D-Glucarate
4.9Rated 4.9 out of 5 stars134 ReviewsFrom $32Key Benefits and Actions† Supports liver & gut detoxification Supports normal estrogen metabolism Supports normal cholesterol levels Who Ne...
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Support the healthy conversion of fat into energy with Acetyl-L-Carnitine.†
Acetyl-L-carnitine—A unique, bioavailable amino acid that supports healthy energy production, brain and nervous system function, and fat metabolism.†

Acetyl-L-Carnitine
Key Benefits and Actions† Supports conversion of fat into energy Supports healthy heart, brain, muscle, and sperm function Supports athletic per...
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