TL;DR If your pre-period symptoms feel overwhelming—not just uncomfortable—it might be more than PMS; it could be PMDD, a more intense and often misunderstood condition linked to hormone sensitivity. While PMS is common and usually manageable, PMDD can deeply affect your mood, energy, and daily life. The good news? You’re not alone, and there are supportive, effective ways to feel better—from lifestyle shifts to supplements and personalized care. Listening to your body, tracking symptoms, and seeking help are powerful steps toward brighter, more balanced days. You deserve compassion, clarity, and support every step of the way.†
What Is Premenstrual Syndrome (PMS)?

Premenstrual Syndrome, or PMS, is a group of physical and emotional symptoms that many women experience in the week or two before their period.
It happens during the luteal phase—the second half of your menstrual cycle—when your body releases more progesterone and estrogen to prepare for a possible pregnancy. Estrogen and progesterone work together to boost serotonin (your ‘calming’ neurotransmitter) during this phase, which is why many women feel calmer and have better sleep during this phase, if everything is in balance.(20-22)
Even though both hormones increase during this time, progesterone becomes the more dominant hormone. However, fluctuations (rising and falling) of either estrogen or progesterone may contribute to heightened sensitivity, mood swings, and physical discomfort in some individuals.
If pregnancy doesn’t occur, those hormone levels drop quickly, which can affect brain chemicals like serotonin that help regulate mood.
This sudden shift often leads to symptoms like mood changes, irritability, bloating, breast tenderness, headaches, fatigue, acne, and food cravings.
High estrogen can also sometimes worsen PMS symptoms in sensitive individuals, but it’s mostly the withdrawal from these hormones that typically triggers PMS.(18,19)
Over 90% of women who menstruate experience at least one symptom that usually improves once their period begins.(1) About 20-40% of women experience significant enough symptoms to meet the criteria for PMS.(23) While these changes can be frustrating, they’re a normal response to the natural rhythm of your cycle.
What Is Premenstrual Dysphoric Disorder (PMDD)?

If your symptoms feel much more intense or harder to manage, it could be PMDD, a more severe form of PMS.
PMDD happens because your body is very sensitive to the natural changes in hormones like estrogen and progesterone before your period. PMDD affects about 3–8% of women who menstruate and can deeply impact their daily life.(2)
These hormone shifts can affect your brain’s chemicals, especially serotonin, which controls mood and emotions.
If you have PMDD, you may find yourself struggling with more debilitating feelings like:
- Extreme sadness or hopelessness
- Overwhelming anger or irritability
- Trouble sleeping or eating
- Difficulty concentrating or making decisions and experiencing brain fog
- Physical symptoms, including intense discomfort that disrupts your daily routine
Certain things can make symptoms worse, like stress or a family history of mood disorders. However, regardless of the cause, your feelings and symptoms are genuine and deserve attention. Know you are not alone, and there are ways to help. PMDD is a recognized medical condition that deserves compassionate care.
Key Differences Between PMDD and PMS
Here’s what you should know so you can recognize what you might be experiencing:
| Feature | PMS | PMDD |
|---|---|---|
| How Bad It Feels | Mild to moderate symptoms | Severe symptoms (at least five) that can disrupt your life |
| How It Affects Mood | Manageable mood swings | Feeling very low or angry, hopeless, or extremely agitated and full of angst |
| Physical Issues | Some discomfort (bloating, pain) | More intense pain and fatigue, brain fog |
| How Long It Lasts | Usually stops when your period starts | Can last through your period, or track through the luteal phase and resolve when your period starts |
| Impact on Daily Life | You can usually keep going | Marked interference with work, school, social activities, or relationships |
Diagnosis: How PMDD and PMS Are Identified

If you think you might have PMDD, one of the best things you can do is start tracking your symptoms daily. This can help you—and your healthcare provider—see patterns and decide the best way to help you.
You might be asked to:
- Write down how you feel every day for at least two cycles
- Notice when symptoms start and stop
- Talk about your mood and physical symptoms openly, especially tough emotional symptoms
It can feel a little overwhelming to talk about, but remember that this process is about supporting you and getting you the right care. You have a voice and know your body best and how it feels more than anyone!
Effective Management Strategies for PMS

If your symptoms feel manageable but annoying, there are some gentle ways you can support yourself:
- Move your body regularly: Exercise—even a walk—can support your mood and offer physical comfort.(3)
- Eat balanced meals: Eating protein and complex carbs helps keep your blood sugar stable. On your plate, eat non-starchy veggies (leafy greens) first, then protein, then fats, then starchy carbs to keep blood sugar and insulin levels balanced.(24) Try to cut back on caffeine, sugar, and salt.
- Rest well: Prioritizing good sleep and keeping bedtime/waking times consistent can support how well you feel and cope with discomfort.
- Manage stress: Find ways that work for you, like breathing exercises, yoga, or time with loved ones.(3)
- Try supplements: Some people find that calcium and vitamin B6 help support comfort during this time, but it’s best to check with a healthcare provider before starting new supplements.†
- Use heat therapy if needed for cramps. Apply a heating pad or hot water bottle to the lower abdomen area. Heat helps relax uterine muscles and boost blood flow, offering pain relief without having to reach for pain medications.
- Use essential oils (diluted into a carrier oil) to support comfort during your period. Peppermint and lavender oil are well known for being beneficial for supporting comfort.
- Drink herbal tea: Ginger, cinnamon, fennel, and chamomile are herbs that can be combined or taken separately as a herbal tea when you have your period. They offer a gentle alternative to support period comfort, relaxed muscles, and calm nerves.
By taking these steps and building good habits, you’re supporting your body holistically every day, not just during “that time of the month!”
Effective Management Strategies for PMDD

If you’re facing more serious symptoms, your care may need to be more personalized.
Here are some options that many find helpful:
- Build on lifestyle habits: Continue exercise, nutrition, sleep routines, and stress management—these are important for everyone.
- Safe supplementation: For example, magnesium and vitamin B6 can support mood and comfort when used carefully.(4)†
- Extra support: If symptoms feel overwhelming, counseling or therapy can help you cope with the emotional impact.
Gentle Ways to Support Your Cycle with Supplements

A thoughtful supplement plan tailored to the phases of your menstrual cycle can support your mood and energy, too.†
For example:
- Taking DIM during the early cycle when estrogen is rising. DIM (diindolylmethane) supports hormonal health by helping your body process estrogen down a less estrogenic pathway. This promotes balanced hormone levels in women who are prone to estrogen dominance.(5,6,7)†
- Supporting serotonin with nutrients after ovulation if your mood drops. Serotonin helps support hormonal health by working with your brain and body to balance mood and emotional well-being, especially as your hormones shift before your period.(8,9,10)†
- Using magnesium and vitamin B6 at night can support good sleep and overall comfort. Magnesium helps your body maintain proper hormone balance, supports muscle comfort, and promotes mood stability as your hormones change before your period. B6 works with magnesium to support healthy mood and physical comfort during your premenstrual phase. This combination offers gentle support for your body as it prepares for your period.(11,12,13)†
- Managing iron levels during your period. Iron plays an important role in supporting your hormonal health during the menstrual cycle by helping keep your hormone production balanced and your energy levels steady, especially since iron is needed for making hemoglobin, which transports oxygen in your blood and supports healthy ovary and uterus function. Heavy menstrual bleeding often results in iron deficiency, which can produce symptoms that overlap with symptoms of hormonal imbalance and make symptoms like fatigue and mood swings worse.(14,15,16)†
- Fish oil, rich in omega-3 fatty acids, may help support your mood during the premenstrual phase, helping you stay cool, calm, and collected. Taking fish oil supplements has been shown to offer support during PMS, making this time of the month more manageable.(17†
Always talk with your healthcare provider before starting new supplements or medications, so you feel safe and supported.
Dr. Lynch’s Menstrual Cycle Support Plan with Supplements by Seeking Health
Dr. Lynch thoughtfully created this plan designed to support healthy hormones and a healthy mood throughout the month:†

DIM+I3C: Take 1 capsule after dinner during the follicular phase, which is days 6-14 roughly. Estrogen levels rise and peak before ovulation, then drop. So take it a week before ovulation, then stop. If you find you need further estrogen support, consider adding Calcium D Glucarate and take it along with the DIM+I3C.†

Serotonin Nutrients or Lithium Orotate: Serotonin levels drop during the luteal phase. Consider taking either of these supplements to support healthy serotonin levels. You may respond better to one or the other, so consider getting both and seeing how you do. You may also do well with one for a few days and then switch over to the other. Start taking this the day after ovulation and maintain until your period starts or your symptoms are healthy.†

Optimal Electrolyte: 1 serving upon waking to support healthy magnesium, taurine, and potassium levels, which are key for mood, menstrual comfort, and hydration.†

Magnesium Plus: Take 1 capsule before bed to support healthy menses and mood. The combination of magnesium and B6 is key for this.†

Optimal Iron: Take 1 capsule for a couple of weeks during menstruation to support healthy iron levels, then discontinue use.†
Fish Oil: Take 1 capsule to support healthy blood flow and mood after dinner. Take each evening.†
The Bottom Line

Facing PMS or PMDD can feel lonely or exhausting, but there’s hope. By learning about your body and seeking care, you’re taking important steps toward feeling better. You don’t have to manage this alone—reach out to trusted health professionals, friends, or support groups. Your experience matters, and with understanding and thoughtful care, bright days are still on the horizon.
References:
- https://pubmed.ncbi.nlm.nih.gov/16734317/
- https://pubmed.ncbi.nlm.nih.gov/38199397/
- https://pubmed.ncbi.nlm.nih.gov/18559957/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9790166/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11583660/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3048776/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7566319/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7073417/
- https://www.ncbi.nlm.nih.gov/books/NBK532307/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10074750/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4161081/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3208934/
- https://pubmed.ncbi.nlm.nih.gov/25276694/
- https://pubmed.ncbi.nlm.nih.gov/11890637/
- https://pubmed.ncbi.nlm.nih.gov/27087396/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3414597/
- https://pubmed.ncbi.nlm.nih.gov/35266254/
- https://my.clevelandclinic.org/health/body/22353-estrogen
- https://www.saintlukeskc.org/health-library/understanding-pms-and-your-cycle
- https://pubmed.ncbi.nlm.nih.gov/20528302/
- https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2014.00380/full
- https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2015.00037/full
- https://www.sciencedirect.com/science/article/pii/S2213398423001550
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10005673/
†These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.