Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
New Year SaleBest SellerOptimal Electrolyte Sticks
SHOP NOW4.7Rated 4.7 out of 5 stars136 Reviews$40$30From$40$30Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$40$40.00 - $204.00(Save 25%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $40.00$40.00 - $204.00$40.00 - $204.00Current price $30$40.00 - $204.00Current price $30 -
Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
New Year SaleRiboflavin Supplement
SHOP NOW4.9Rated 4.9 out of 5 stars117 Reviews$24$18From$24$18Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...
View full detailsOriginal price $24 - Original price $144Original price $24 - Original price $144Original price $72$24$24.00 - $122.40(Save 25%)$24.00 - $122.40Original price $24.00 - Original price $144.00Original price $24.00 - Original price $144.00Original price $24.00$24.00 - $122.40$24.00 - $122.40Current price $18$24.00 - $122.40Current price $18 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
New Year SaleMagnesium Malate Chewable
SHOP NOW4.8Rated 4.8 out of 5 stars135 Reviews$22$16.50From$22$16.50Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$22$22.00 - $112.20(Save 25%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $22.00$22.00 - $112.20$22.00 - $112.20Current price $16.50$22.00 - $112.20Current price $16.50 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
New Year SaleFolinic Acid Lozenge
SHOP NOW4.8Rated 4.8 out of 5 stars208 Reviews$20$15From$20$15Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$20$20.00 - $102.00(Save 25%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $20.00$20.00 - $102.00$20.00 - $102.00Current price $15$20.00 - $102.00Current price $15 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
New Year SaleBest SellerImprovedOptimal Electrolyte
SHOP NOW4.6Rated 4.6 out of 5 stars1,618 Reviews$38$28.50From$38$28.50Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$38$38.00 - $193.80(Save 25%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $38.00$38.00 - $193.80$38.00 - $193.80Current price $28.50$38.00 - $193.80Current price $28.50 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
New Year SaleMagnesium Malate Powder
SHOP NOW4.7Rated 4.7 out of 5 stars193 Reviews$22$16.50From$22$16.50Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$22$22.00 - $112.20(Save 25%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $22.00$22.00 - $112.20$22.00 - $112.20Current price $16.50$22.00 - $112.20Current price $16.50
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A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
New Year SaleBest SellerOptimal Electrolyte Sticks
SHOP NOW4.7Rated 4.7 out of 5 stars136 Reviews$40$30From$40$30Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$40$40.00 - $204.00(Save 25%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $40.00$40.00 - $204.00$40.00 - $204.00Current price $30$40.00 - $204.00Current price $30 -
Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
New Year SaleRiboflavin Supplement
SHOP NOW4.9Rated 4.9 out of 5 stars117 Reviews$24$18From$24$18Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...
View full detailsOriginal price $24 - Original price $144Original price $24 - Original price $144Original price $72$24$24.00 - $122.40(Save 25%)$24.00 - $122.40Original price $24.00 - Original price $144.00Original price $24.00 - Original price $144.00Original price $24.00$24.00 - $122.40$24.00 - $122.40Current price $18$24.00 - $122.40Current price $18 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
New Year SaleMagnesium Malate Chewable
SHOP NOW4.8Rated 4.8 out of 5 stars135 Reviews$22$16.50From$22$16.50Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$22$22.00 - $112.20(Save 25%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $22.00$22.00 - $112.20$22.00 - $112.20Current price $16.50$22.00 - $112.20Current price $16.50 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
New Year SaleFolinic Acid Lozenge
SHOP NOW4.8Rated 4.8 out of 5 stars208 Reviews$20$15From$20$15Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$20$20.00 - $102.00(Save 25%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $20.00$20.00 - $102.00$20.00 - $102.00Current price $15$20.00 - $102.00Current price $15 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
New Year SaleBest SellerImprovedOptimal Electrolyte
SHOP NOW4.6Rated 4.6 out of 5 stars1,618 Reviews$38$28.50From$38$28.50Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$38$38.00 - $193.80(Save 25%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $38.00$38.00 - $193.80$38.00 - $193.80Current price $28.50$38.00 - $193.80Current price $28.50 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
New Year SaleMagnesium Malate Powder
SHOP NOW4.7Rated 4.7 out of 5 stars193 Reviews$22$16.50From$22$16.50Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$22$22.00 - $112.20(Save 25%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $22.00$22.00 - $112.20$22.00 - $112.20Current price $16.50$22.00 - $112.20Current price $16.50
-
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
New Year SaleBest SellerOptimal Electrolyte Sticks
SHOP NOW4.7Rated 4.7 out of 5 stars136 Reviews$40$30From$40$30Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$40$40.00 - $204.00(Save 25%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $40.00$40.00 - $204.00$40.00 - $204.00Current price $30$40.00 - $204.00Current price $30 -
Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
New Year SaleRiboflavin Supplement
SHOP NOW4.9Rated 4.9 out of 5 stars117 Reviews$24$18From$24$18Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...
View full detailsOriginal price $24 - Original price $144Original price $24 - Original price $144Original price $72$24$24.00 - $122.40(Save 25%)$24.00 - $122.40Original price $24.00 - Original price $144.00Original price $24.00 - Original price $144.00Original price $24.00$24.00 - $122.40$24.00 - $122.40Current price $18$24.00 - $122.40Current price $18 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
New Year SaleMagnesium Malate Chewable
SHOP NOW4.8Rated 4.8 out of 5 stars135 Reviews$22$16.50From$22$16.50Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$22$22.00 - $112.20(Save 25%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $22.00$22.00 - $112.20$22.00 - $112.20Current price $16.50$22.00 - $112.20Current price $16.50 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
New Year SaleFolinic Acid Lozenge
SHOP NOW4.8Rated 4.8 out of 5 stars208 Reviews$20$15From$20$15Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$20$20.00 - $102.00(Save 25%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $20.00$20.00 - $102.00$20.00 - $102.00Current price $15$20.00 - $102.00Current price $15 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
New Year SaleBest SellerImprovedOptimal Electrolyte
SHOP NOW4.6Rated 4.6 out of 5 stars1,618 Reviews$38$28.50From$38$28.50Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$38$38.00 - $193.80(Save 25%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $38.00$38.00 - $193.80$38.00 - $193.80Current price $28.50$38.00 - $193.80Current price $28.50 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
New Year SaleMagnesium Malate Powder
SHOP NOW4.7Rated 4.7 out of 5 stars193 Reviews$22$16.50From$22$16.50Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$22$22.00 - $112.20(Save 25%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $22.00$22.00 - $112.20$22.00 - $112.20Current price $16.50$22.00 - $112.20Current price $16.50
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Acetyl-L-carnitine—A unique, bioavailable amino acid that supports healthy energy production, brain and nervous system function, and fat metabolism.†
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