Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,617 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
SHOP NOW $254.9Rated 4.9 out of 5 stars281 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full detailsOriginal price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50(Save 67%)$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
SHOP NOW $224.8Rated 4.8 out of 5 stars133 ReviewsFrom $22Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
SaleBOGOBrain Nutrients
SHOP NOW $504.6Rated 4.6 out of 5 stars100 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
View full detailsOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00(Save 67%)$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars136 ReviewsFrom $40Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00(Save 67%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars205 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars190 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,617 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
SHOP NOW $254.9Rated 4.9 out of 5 stars281 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full detailsOriginal price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50(Save 67%)$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
SHOP NOW $224.8Rated 4.8 out of 5 stars133 ReviewsFrom $22Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
SaleBOGOBrain Nutrients
SHOP NOW $504.6Rated 4.6 out of 5 stars100 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
View full detailsOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00(Save 67%)$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars136 ReviewsFrom $40Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00(Save 67%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars205 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars190 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,617 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
SHOP NOW $254.9Rated 4.9 out of 5 stars281 ReviewsFrom $25Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full detailsOriginal price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50(Save 67%)$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
SHOP NOW $224.8Rated 4.8 out of 5 stars133 ReviewsFrom $22Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
SaleBOGOBrain Nutrients
SHOP NOW $504.6Rated 4.6 out of 5 stars100 ReviewsFrom $50Provides energy and nutrition for your brain - quickly. Supports healthy mental energy, mood, concentration, and focus Enhances the effectiveness...
View full detailsOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00(Save 67%)$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars136 ReviewsFrom $40Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredients for hydrat...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00(Save 67%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars205 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars190 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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