Methylation Pathway

Methylation Pathway

The primary goal of the Methylation Pathway is to produce the primary methyl donor called s-adenosylmethionine - aka SAMe. Once formed, SAMe supports over 200 essential reactions ranging from creatine and phosphatidylcholine synthesis to neurotransmitter synthesis and breakdown, to detoxification of xenobiotics. The formation of SAMe is quite difficult and so can be its utilization. Identifying potential blockages in either area and ensuring adequate nutrition to form and utilize SAMe can be key steps toward optimal health. Some of the key nutrients of the Methylation Pathway are L-5-MTHF, methylcobalamin, methionine, magnesium, zinc and SAMe. Supplementing with Optimal PC and Optimal Creatine may help to preserve these fundamental nutrients of the Methylation Pathway. Phosphatidylcholine and creatine require up to 80% of the body’s methylation to produce.*

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