Skip to content
For a Limited Time - Buy 1, Get 1 Free!
For a Limited Time - Buy 1, Get 1 Free!

Hydroxo B12 - 60 Lozenges

Rated 4.8 out of 5 stars
162 Reviews

Hydroxo B12 - 60 Lozenges

Original price $21.95 - Original price $111.96
Original price
You save: $$$ (%)
$21.95 - $111.96
Current price
You save: $$$ (%)

Key Benefits and Actions

Key Benefits and Actions

  • Most stable form of methyl-free B12
  • Powerful energy and methylation support
  • Supports healthy detoxification

Who Needs Hydroxo B12

Are you sensitive to methyl B12 products? Are you exposed to toxins such as smoke and other air pollutants?

Vitamin B12 is well known for its ability to support energy production. A specific form of B12 called hydroxocobalamin (hydroxo B12) plays a unique role in maintaining healthy detoxification pathways. In addition, this methyl-free B12 is excellent for those sensitive to methyl groups.

Hydroxo B12 by Seeking Health contains 2,000 mcg of hydroxocobalamin in an well-digested lozenge.

As the most stable form of vitamin B12, hydroxocobalamin appears to circulate longer in the human body than all other forms. ‘Hydroxo’ B12 can easily convert to both ‘adeno’ and ‘methyl’ forms to support healthy methylation, detoxification, and energy production.

Due to its shape, hydroxo B12 supports the normal detoxification of toxins present in environmental exposures, such as smoke inhalation and other pollutants. While nitric oxide is vital for blood flow, high levels may contribute to headaches and migraines. Hydroxocobalamin may help to support balanced nitric oxide levels in the body.

Vitamin B12 deficiency is common. It is one of the most difficult nutrients for your body to absorb and utilize. Vitamin B12 deficiency can be characterized by fatigue, memory issues, and tingling in your toes or fingers.

Causes of vitamin B12 deficiency can include:

  • Malabsorption
  • Low stomach acid
  • Vegetarian or vegan diet
  • Insufficient intrinsic factor
  • Slowed transcobalamin enzymes

It’s critical to consume B12 in a bioavailable form that your body can readily utilize. Ideally, B12 is in a format designed for optimal digestion, absorption, and utilization, such as a lozenge. If you’re sensitive to methylated nutrients, you also want a supplement free of methyl groups.

Hydroxo B12 provides bioavailable, methyl-free B12 in a delicious lozenge for fast-acting support.

Hydroxo B12 supports healthy:

  • Methylation processes
  • Energy production
  • Detoxification
  • Homocysteine levels
  • Sensitivity to methyl groups

With this potent and delicious vitamin B12 supplement, optimal energy has never been easier!

Customer Review

Finally, A B12 my body likes!

I have tried a few different brands of methylcobalamin which is the form that has always been recommended to me. I have never muscle tested well for them. My numbers have been high as well. This one has been great. Muscle test for it and my body is happy. I don't need my adrenal support any more. Yea! ~Marilyn

Key Ingredients In Hydroxo B12

  • Hydroxocobalamin: A non-methylated form of B12 that quickly converts to adeno B12 and methyl B12 in the body. It supports healthy energy production and helps the body to utilize folate for methylation processes. Hydroxo B12 also supports the normal detoxification of toxins present in environmental exposures, such as smoke and other pollutants.

Why Hydroxo B12 Works

Hydroxocobalamin (Hydroxo B12) is a unique substance. Due to its shape, it can readily bind to certain compounds.

Nitric oxide is known as a beneficial substance that relaxes blood vessels and lowers blood pressure. However, it is possible to have too much of a good thing. When there is excess nitric oxide in your body, a harmful compound called peroxynitrite can form and cause cellular damage. Hydroxocobalamin appears to assist in the processing of excessive nitric oxide. This may help cells to maintain healthy nitric oxide levels.

Exposure to certain metal polishing chemicals, insecticides, and smoke from house fires can cause cyanide levels to go beyond healthy ranges. Most dietary supplements contain B12 as cyanocobalamin. Before it can be used, your liver must first convert cyanocobalamin into an active form and discard the cyanide. An alternative form of B12 such as hydroxocobalamin may be a healthier option.

Here at Seeking Health, you’ll never find the cyanide-containing form, cyanocobalamin, which requires extra steps for utilization in the body. Instead, you’ll only find bioavailable forms of vitamin B12 that your body can quickly recognize and utilize.

Hydroxocobalamin is known as one of the most stable forms of B12. It appears to circulate longer in the human body than all other forms. Hydroxo B12 can readily convert into cobalamin that your body uses to make both methylcobalamin and adenosylcobalamin.

Because of its versatile shape, hydroxocobalamin indirectly supports many critical processes. These include healthy homocysteine breakdown, MTR genetic variations, and methylation processes. Those with MTHFR gene variants may benefit from additional B12 support.

By converting to cobalamin, Hydroxo B12 also supports energy production. Cobalamin is readily converted to adenosylcobalamin in the mitochondria. Here it is used to facilitate ATP (energy) production.

Some people experience adverse reactions to methylated nutrients. These can include nervousness, headaches, or rapid heartbeat after taking methylcobalamin or methylfolate. Hydroxo B12 is free from methyl groups while still providing potent and fast-acting B12.

Support healthy B12 levels and detoxification (without the side effects of methyl groups!) with Hydroxo B12.

Hydroxo B12
Supplement Facts

Serving Size: 1 Lozenge
Servings Per Container: 60

Vitamin B12 (as hydroxocobalamin) 2,000 mcg 83,333%
DV = Daily Value

Other Ingredients: Xylitol, ascorbyl palmitate, natural cherry flavor, malic acid, and silica.

  • Suitable For: Vegetarians and Vegans
  • Age Suitability: Adults
  • Delivery Method: Lozenges
  • How To Store: Keep closed in a cool, dry place out of reach of children.

Free Of: Eggs, Fish, Gluten, GMO, Milk, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use Hydroxo B12

Suggested Use

Take 1 lozenge daily or as directed by your healthcare professional. Lozenge may be broken into smaller pieces if lower dosage is desired.


Children and pregnant or breastfeeding women should consult their healthcare provider for medical advice prior to use. Do not use if tamper seal is damaged.

How to Enhance Hydroxo B12


Consider Pulsing

Dr. Ben Lynch recommends using certain dietary supplements based on your need for them. Start with a partial serving and increase slowly over time to the full serving, only if needed. When you start feeling good, consider reducing the serving size, skipping days, or pausing supplementation. Then take again when you feel you need it (stressful day, traveling, chemical exposure, etc.), hence "pulsing." Work with your qualified healthcare practitioner to determine what's best for you.


Pairs Well With

PQQ Lozenge, to support a healthy response to oxidative stress. B12 functions best under low oxidative stress levels. Folinic Acid Lozenge, a methyl-free, bioavailable form of folate required for methylation processes. Optimal Magnesium, to support energy-dependent enzymes.


Clean Your Genes

After years of suffering from unexplainable health issues, Dr. Ben Lynch, ND discovered the root cause - "dirty" genes. In his best-selling book, Dirty Genes, Dr. Ben Lynch describes the steps you can take to promote optimal epigenetic health. Ready to get started? Click here to take the Dirty Genes Quiz to find which of your genes are dirty!

Why Choose Seeking Health

Here at Seeking Health, we are committed to providing you the best in bioavailable supplements, methylation support, prenatal vitamins, genetic analysis tools, and more.

We strive to go above and beyond the average supplement company, which is why we allocate significant resources to testing all of our supplements for purity, potency, and label claims.

  • Third-party tested for heavy
    metals, microbials, and potency
  • Scientifically formulated by Dr. Ben Lynch, ND
  • Manufactured in the USA from globally
    sourced ingredients
  • Nutrients in their bioavailable
    forms for optimal absorption
  • cGMP facility registered by NSF International
Purity & Potency Tested & Assured
Scientifically Formulated by Dr. Ben Lynch
Manufactured in the USA from globally sourced ingredients third-party independently tested
Bioavailable Nutrients

FAQs for Hydroxo B12

What is the purpose of each ingredient in Hydroxo B12?

Ingredients Purpose
Vitamin B12 (as hydroxocobalamin) Non-methylated form of B12; Quickly converts to methyl B12 in the body; Targets energy production and helps utilize folate for methylation processes; Supports the normal detoxification of toxins present in environmental exposures, such as smoke inhalation and other pollutants

Who is Hydroxo B12 intended for?

Hydroxo B12 is for individuals seeking a potent, non-methylated vitamin B12 supplement. This methyl-free form readily converts to methylcobalamin, the active coenzyme form of B12. It includes no methyl groups for those who are sensitive.

Hydroxo B12 also plays a role in the regulation of normal and healthy levels of both nitric oxide and cyanide. detoxification of nitric oxide and cyanide.

Which Vitamin B12 is right for me?

Check out this Vitamin B12 Supplement Comparison Chart.

This article will help you determine if you need a methyl-free supplement.

If you have a question that's not addressed
here, see all frequently asked questions.


Do you have Questions
for this Product?


What our customers say

Real reviews from real customers.

Product reviews solely reflect the views and opinions expressed by the contributors and not those of SeekingHealth. SeekingHealth does not verify or endorse any claims made in these reviews. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
Rated 4.8 out of 5 stars
Based on 162 reviews
Total 5 star reviews: 144 Total 4 star reviews: 8 Total 3 star reviews: 5 Total 2 star reviews: 1 Total 1 star reviews: 4
94%would recommend this product
162 reviews
  • ES
    Eileen S.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    Will update in the future

    Not sure yet. Had to stop them for a while. Will update when I can.

  • LR
    Laurie R.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Hydroxide B 12

    They work amazing.

  • NB
    Nick B.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    5 days ago
    They work great

    These lozenges are easy to take, to let one dissolve in my mouth every morning. And they give me energy!

Reviews LoadedReviews Added
These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.