Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
Lithium Orotate—Provides a low serving of lithium (5 mg per capsule) as lithium orotate attached to the natural compound orotic acid for optimal bioavailability and efficient absorption.†
Lithium Orotate
SHOP NOW $224.9Rated 4.9 out of 5 stars109 ReviewsFrom $22Key Benefits and Actions† Supports feelings of calm and well-being Natural mood support Supports memory, brain, and neurological health Who Nee...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars75 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
SaleBOGODopamine Nutrients
SHOP NOW $464.6Rated 4.6 out of 5 stars52 ReviewsFrom $46Key Benefits:† Supports healthy mood and motivation Supports healthy learning and memory Supports healthy libido and drive Dopamine Nutrients w...
View full detailsOriginal price $46 - Original price $234.60Original priceSALE$46.00 - $234.60$46.00 - $234.60Original price $46.00 - Original price $234.60Original price$46.00 - $234.60$46.00 - $234.60Current price $46$46.00 - $234.60Current price $46 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars205 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
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Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars200 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars189 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
Lithium Orotate—Provides a low serving of lithium (5 mg per capsule) as lithium orotate attached to the natural compound orotic acid for optimal bioavailability and efficient absorption.†
Lithium Orotate
SHOP NOW $224.9Rated 4.9 out of 5 stars109 ReviewsFrom $22Key Benefits and Actions† Supports feelings of calm and well-being Natural mood support Supports memory, brain, and neurological health Who Nee...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars75 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
SaleBOGODopamine Nutrients
SHOP NOW $464.6Rated 4.6 out of 5 stars52 ReviewsFrom $46Key Benefits:† Supports healthy mood and motivation Supports healthy learning and memory Supports healthy libido and drive Dopamine Nutrients w...
View full detailsOriginal price $46 - Original price $234.60Original priceSALE$46.00 - $234.60$46.00 - $234.60Original price $46.00 - Original price $234.60Original price$46.00 - $234.60$46.00 - $234.60Current price $46$46.00 - $234.60Current price $46 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars205 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars200 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars189 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
Lithium Orotate—Provides a low serving of lithium (5 mg per capsule) as lithium orotate attached to the natural compound orotic acid for optimal bioavailability and efficient absorption.†
Lithium Orotate
SHOP NOW $224.9Rated 4.9 out of 5 stars109 ReviewsFrom $22Key Benefits and Actions† Supports feelings of calm and well-being Natural mood support Supports memory, brain, and neurological health Who Nee...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars75 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Foster a healthy mood, motivation, learning, and memory with Dopamine Nutrients.†
Dopamine Nutrients—Designed to support healthy dopamine levels and the health of the cells that make it with key ingredients like L-Tyrosine, Ginkgo Biloba Extract, and Royal Jelly Concentrate.†
SaleBOGODopamine Nutrients
SHOP NOW $464.6Rated 4.6 out of 5 stars52 ReviewsFrom $46Key Benefits:† Supports healthy mood and motivation Supports healthy learning and memory Supports healthy libido and drive Dopamine Nutrients w...
View full detailsOriginal price $46 - Original price $234.60Original priceSALE$46.00 - $234.60$46.00 - $234.60Original price $46.00 - Original price $234.60Original price$46.00 - $234.60$46.00 - $234.60Current price $46$46.00 - $234.60Current price $46 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars205 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars200 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars189 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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