Skip to content
BUY 1, GET 2 FREE! Mix & Match - Selected items for a limited time only.
BUY 1, GET 2 FREE! Mix & Match - Selected items for a limited time only.

Dirty Genes™ - COMT Slow Support

The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.


Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene

The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.


Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.


To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.


Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.

Read More

Shop by

What our customers say

Real Google reviews from real customers.

Claire C.

Awesome

Keeps me hydrated so I can avoid breaking my fast until lunch time! I love the fizziness of the seltzer flavor.

Cheryl

Best probiotic for women

I love this probiotic. I often get flora imbalances since having my third child. I have been using this for 4 months a few times per week, and have had no issues since.

Megan

Best Prenatal

Love optimal prenatal. I tried several different brands before trying these and they are by far the best!

Claire C.

Awesome

Keeps me hydrated so I can avoid breaking my fast until lunch time! I love the fizziness of the seltzer flavor.

Cheryl

Best probiotic for women

I love this probiotic. I often get flora imbalances since having my third child. I have been using this for 4 months a few times per week, and have had no issues since.

†These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.