MTHFR Supplements for Targeted Methylation Support
Most people have never heard of MTHFR until a test result stops them in their tracks. But if you've recently discovered you carry an MTHFR gene variant, you're not alone. The good news is that support is available.
Most people have never heard of MTHFR until a test result stops them in their tracks. But if you've recently discovered you carry an MTHFR gene variant, you're not alone. The good news is that support is available.
MTHFR is a gene that helps your body convert folate and B12 into forms it can use. When this gene has a common variation, that conversion process becomes less efficient. Your body works harder than it needs to.
That extra strain has real consequences. It can show up as elevated homocysteine levels, low energy, and detoxification challenges.
The good news is that targeted supplementation can make a real difference.† Because the issue is about bioavailability, standard folic acid and B12 often don't cut it.
Your body uses nutrients that are already in their active, methylated form. That way, it can efficiently absorb and utilize them.
Key nutrients include methylcobalamin (methyl-B12), L-5-MTHF (methylfolate), SAMe, creatine, and phosphatidylcholine. These work with your body's methylation processes rather than adding strain to them.
MTHFR Supplements Designed to Work With Your Body
Seeking Health specializes in MTHFR support. You'll find MTHFR vitamins and products built specifically around these needs.
Optimal Multivitamin is a great starting point for comprehensive, methylated nutrient support. HomocysteX Plus supports healthy homocysteine conversion. B Complex Plus targets MTHFR enzyme function directly. It's a standalone B vitamin formula that fits easily into your daily routine.†
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Start your day off right by giving your overall health and well-being top priority with Multivitamin One!†
Multivitamin One—A one-a-day multivitamin containing active forms of your essential daily nutrients in a well-absorbed capsule formulated without vitamin C, magnesium, calcium, or iron to allow customization.†
Best SellerHSA / FSAMultivitamin One
SHOP NOW $374.9Rated 4.9 out of 5 stars462 ReviewsFrom $37Formulated for MTHFR with zero folic acid using methylfolate, dual active B12, chelated minerals, and antioxidant support nutrients like glutathio...
View full detailsOriginal price $37 - Original price $222Original price $37 - Original price $222Original price $111$111$37.00 - $188.70Save 67%$37.00 - $188.70Original price $37.00 - Original price $222.00Original price $37.00 - Original price $222.00Original price $111.00$37.00 - $188.70$37.00 - $188.70Current price $37$37.00 - $188.70Current price $37 -
Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!†
PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.†
Best SellerPQQ Lozenge
SHOP NOW $354.7Rated 4.7 out of 5 stars325 ReviewsFrom $35Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50Save 67%$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerHSA / FSAOptimal Electrolyte
SHOP NOW $404.6Rated 4.6 out of 5 stars1,674 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!†
Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.†
Best SellerHSA / FSAMethyl B12 with L-Methylfolate
SHOP NOW $274.9Rated 4.9 out of 5 stars885 ReviewsFrom $27A delicious, fast-absorbing lozenge that bypasses genetic bottlenecks to support healthy methylation, balanced homocysteine levels, mental clarity...
View full detailsOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars152 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Coming SoonEstrogen Nutrients
From $45For women experiencing occasional bloating, breast tenderness, mood shifts, and menstrual discomfort associated with PMS and their monthly cycle, ...
View full detailsOriginal price $45 - Original price $243Original priceSALE$45.00 - $243.00$45.00 - $243.00Original price $45.00 - Original price $243.00Original price$45.00 - $243.00$45.00 - $243.00Current price $45$45.00 - $243.00Current price $45 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars221 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Bile Nutrients.†
Bile Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Out of Stock
Bile Nutrients
4.7Rated 4.7 out of 5 stars157 ReviewsFrom $42Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with or without a gal...
View full detailsOriginal price $42 - Original price $252Original price $42 - Original price $252Original price $126$126$42.00 - $214.20Save 67%$42.00 - $214.20Original price $42.00 - Original price $252.00Original price $42.00 - Original price $252.00Original price $126.00$42.00 - $214.20$42.00 - $214.20Current price $42$42.00 - $214.20Current price $42Out of Stock -
Give your baby the best start by supporting healthy spine and brain development with Prenatal Essential Chewable!†
Prenatal Essential Chewable—A targeted prenatal vitamin formulated by epigenetics expert Dr. Ben Lynch ND that provides the foundational basics needed for a healthy pregnancy in an easy-to-take chewable.†
Prenatal Essentials Chewable
SHOP NOW $484.3Rated 4.3 out of 5 stars47 ReviewsFrom $48Provides the foundational nutrients you need to support healthy fertility, pregnancy, and breastfeeding in a delicious, easy-to-chew tablet with b...
View full detailsOriginal price $48 - Original price $288Original price $48 - Original price $288Original price $144$144$48.00 - $244.80Save 67%$48.00 - $244.80Original price $48.00 - Original price $288.00Original price $48.00 - Original price $288.00Original price $144.00$48.00 - $244.80$48.00 - $244.80Current price $48$48.00 - $244.80Current price $48
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Start your day off right by giving your overall health and well-being top priority with Multivitamin One!†
Multivitamin One—A one-a-day multivitamin containing active forms of your essential daily nutrients in a well-absorbed capsule formulated without vitamin C, magnesium, calcium, or iron to allow customization.†
Best SellerHSA / FSAMultivitamin One
SHOP NOW $374.9Rated 4.9 out of 5 stars462 ReviewsFrom $37Formulated for MTHFR with zero folic acid using methylfolate, dual active B12, chelated minerals, and antioxidant support nutrients like glutathio...
View full detailsOriginal price $37 - Original price $222Original price $37 - Original price $222Original price $111$111$37.00 - $188.70Save 67%$37.00 - $188.70Original price $37.00 - Original price $222.00Original price $37.00 - Original price $222.00Original price $111.00$37.00 - $188.70$37.00 - $188.70Current price $37$37.00 - $188.70Current price $37 -
Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!†
PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.†
Best SellerPQQ Lozenge
SHOP NOW $354.7Rated 4.7 out of 5 stars325 ReviewsFrom $35Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50Save 67%$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerHSA / FSAOptimal Electrolyte
SHOP NOW $404.6Rated 4.6 out of 5 stars1,674 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!†
Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.†
Best SellerHSA / FSAMethyl B12 with L-Methylfolate
SHOP NOW $274.9Rated 4.9 out of 5 stars885 ReviewsFrom $27A delicious, fast-absorbing lozenge that bypasses genetic bottlenecks to support healthy methylation, balanced homocysteine levels, mental clarity...
View full detailsOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars152 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Coming SoonEstrogen Nutrients
From $45For women experiencing occasional bloating, breast tenderness, mood shifts, and menstrual discomfort associated with PMS and their monthly cycle, ...
View full detailsOriginal price $45 - Original price $243Original priceSALE$45.00 - $243.00$45.00 - $243.00Original price $45.00 - Original price $243.00Original price$45.00 - $243.00$45.00 - $243.00Current price $45$45.00 - $243.00Current price $45 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars221 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Bile Nutrients.†
Bile Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Out of Stock
Bile Nutrients
4.7Rated 4.7 out of 5 stars157 ReviewsFrom $42Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with or without a gal...
View full detailsOriginal price $42 - Original price $252Original price $42 - Original price $252Original price $126$126$42.00 - $214.20Save 67%$42.00 - $214.20Original price $42.00 - Original price $252.00Original price $42.00 - Original price $252.00Original price $126.00$42.00 - $214.20$42.00 - $214.20Current price $42$42.00 - $214.20Current price $42Out of Stock -
Give your baby the best start by supporting healthy spine and brain development with Prenatal Essential Chewable!†
Prenatal Essential Chewable—A targeted prenatal vitamin formulated by epigenetics expert Dr. Ben Lynch ND that provides the foundational basics needed for a healthy pregnancy in an easy-to-take chewable.†
Prenatal Essentials Chewable
SHOP NOW $484.3Rated 4.3 out of 5 stars47 ReviewsFrom $48Provides the foundational nutrients you need to support healthy fertility, pregnancy, and breastfeeding in a delicious, easy-to-chew tablet with b...
View full detailsOriginal price $48 - Original price $288Original price $48 - Original price $288Original price $144$144$48.00 - $244.80Save 67%$48.00 - $244.80Original price $48.00 - Original price $288.00Original price $48.00 - Original price $288.00Original price $144.00$48.00 - $244.80$48.00 - $244.80Current price $48$48.00 - $244.80Current price $48
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Start your day off right by giving your overall health and well-being top priority with Multivitamin One!†
Multivitamin One—A one-a-day multivitamin containing active forms of your essential daily nutrients in a well-absorbed capsule formulated without vitamin C, magnesium, calcium, or iron to allow customization.†
Best SellerHSA / FSAMultivitamin One
SHOP NOW $374.9Rated 4.9 out of 5 stars462 ReviewsFrom $37Formulated for MTHFR with zero folic acid using methylfolate, dual active B12, chelated minerals, and antioxidant support nutrients like glutathio...
View full detailsOriginal price $37 - Original price $222Original price $37 - Original price $222Original price $111$111$37.00 - $188.70Save 67%$37.00 - $188.70Original price $37.00 - Original price $222.00Original price $37.00 - Original price $222.00Original price $111.00$37.00 - $188.70$37.00 - $188.70Current price $37$37.00 - $188.70Current price $37 -
Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!†
PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.†
Best SellerPQQ Lozenge
SHOP NOW $354.7Rated 4.7 out of 5 stars325 ReviewsFrom $35Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50Save 67%$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerHSA / FSAOptimal Electrolyte
SHOP NOW $404.6Rated 4.6 out of 5 stars1,674 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!†
Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.†
Best SellerHSA / FSAMethyl B12 with L-Methylfolate
SHOP NOW $274.9Rated 4.9 out of 5 stars885 ReviewsFrom $27A delicious, fast-absorbing lozenge that bypasses genetic bottlenecks to support healthy methylation, balanced homocysteine levels, mental clarity...
View full detailsOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars152 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Coming SoonEstrogen Nutrients
From $45For women experiencing occasional bloating, breast tenderness, mood shifts, and menstrual discomfort associated with PMS and their monthly cycle, ...
View full detailsOriginal price $45 - Original price $243Original priceSALE$45.00 - $243.00$45.00 - $243.00Original price $45.00 - Original price $243.00Original price$45.00 - $243.00$45.00 - $243.00Current price $45$45.00 - $243.00Current price $45 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars221 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Bile Nutrients.†
Bile Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Out of Stock
Bile Nutrients
4.7Rated 4.7 out of 5 stars157 ReviewsFrom $42Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with or without a gal...
View full detailsOriginal price $42 - Original price $252Original price $42 - Original price $252Original price $126$126$42.00 - $214.20Save 67%$42.00 - $214.20Original price $42.00 - Original price $252.00Original price $42.00 - Original price $252.00Original price $126.00$42.00 - $214.20$42.00 - $214.20Current price $42$42.00 - $214.20Current price $42Out of Stock -
Give your baby the best start by supporting healthy spine and brain development with Prenatal Essential Chewable!†
Prenatal Essential Chewable—A targeted prenatal vitamin formulated by epigenetics expert Dr. Ben Lynch ND that provides the foundational basics needed for a healthy pregnancy in an easy-to-take chewable.†
Prenatal Essentials Chewable
SHOP NOW $484.3Rated 4.3 out of 5 stars47 ReviewsFrom $48Provides the foundational nutrients you need to support healthy fertility, pregnancy, and breastfeeding in a delicious, easy-to-chew tablet with b...
View full detailsOriginal price $48 - Original price $288Original price $48 - Original price $288Original price $144$144$48.00 - $244.80Save 67%$48.00 - $244.80Original price $48.00 - Original price $288.00Original price $48.00 - Original price $288.00Original price $144.00$48.00 - $244.80$48.00 - $244.80Current price $48$48.00 - $244.80Current price $48
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Support the healthy conversion of fat into energy with Acetyl-L-Carnitine.†
Acetyl-L-carnitine—A unique, bioavailable amino acid that supports healthy energy production, brain and nervous system function, and fat metabolism.†
Acetyl-L-Carnitine
Key Benefits and Actions† Supports conversion of fat into energy Supports healthy heart, brain, muscle, and sperm function Supports athletic per...
View full details