L-Methylfolate Supplements
L-methylfolate is the most abundant form of folate in your body. It is also referred to as active folate or L-5-MTHF. Other types of folate need to be converted into active forms. People with MTHFR gene variants may not be able to activate folic acid. If you are low on this critical nutrient, your methylation cycle won’t work effectively.
Methylation is essential for regulating gene expression and controlling how your DNA works. L-methylfolate supports healthy red blood cells, mental health, and normal homocysteine levels.
L-methylfolate is the most abundant form of folate in your body. It is also referred to as active folate or L-5-MTHF. Other types of folate need to be converted into active forms. People with MTHFR gene variants may not be able to activate folic acid. If you are low on this critical nutrient, your methylation cycle won’t work effectively.
Methylation is essential for regulating gene expression and controlling how your DNA works. L-methylfolate supports healthy red blood cells, mental health, and normal homocysteine levels. It is found in foods like leafy greens and liver. If you aren’t eating a lot of these, you may benefit from a dietary supplement to support healthy folate levels.†
Seeking Health’s L-methylfolate supplements include L-5-MTHF and Active B12 with L-5-MTHF. You can also get Optimal Prenatal and Optimal Multivitamin, which provide folate along with active vitamin B12 (methylcobalamin), calcium, and other important vitamins and minerals.
Check out this Folate Comparison Chart to select the right folate for you.
Explore L-methylfolate supplementation options below.
If you find that methylated supplements make you feel jittery or upset, use this comparison chart to learn about the differences between methylated and non-methylated products or check out this article.
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Buy 1, Get 2 FREE*Optimal Man - 120 Capsules
4.8Rated 4.8 out of 540 Reviews Based on 40 reviewsFrom $59.95As a father, your genetics are passed along to your child, as you may well know. But did you know that your genes can change expression based on yo...
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Prenatal Essentials - 60 Capsules
4.9Rated 4.9 out of 5126 Reviews Based on 126 reviewsFrom $32.95Do you need a prenatal supplement without an overload of excess nutrients? Are you a pregnant mother already eating a healthy, well-balanced diet? ...
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Best SellerBonus RewardsMultivitamin One - 45 Vegetarian Capsules
4.9Rated 4.9 out of 5240 Reviews Based on 240 reviewsFrom $32.95Multivitamin One by Seeking Health provides a wide variety of nutrients in well-absorbed or active forms in a convenient capsule format. Unlike our...
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Bonus RewardsPrenatal Essentials Chewable - 60 Tablets
4.5Rated 4.5 out of 5182 Reviews Based on 182 reviewsFrom $42.95Prenatal Essentials Chewable offers a specialized prenatal formula designed to help meet the high nutritional needs of women who are pregnant or pr...
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Optimal Prenatal Powder – 15 Servings
4.6Rated 4.6 out of 5223 Reviews Based on 223 reviewsFrom $44.96Optimal Prenatal Powder by Seeking Health provides a comprehensive prenatal formula with a unique blend of amino acids, chelated minerals, and vita...
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Buy 1, Get 2 FREE*Optimal Multivitamin Plus - 240 Capsules
4.9Rated 4.9 out of 574 Reviews Based on 74 reviewsFrom $72.95Optimal Multivitamin Plus by Seeking Health is a complete natural daily multivitamin and mineral supplement with active B vitamins and L-5-MTHF. Op...
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Buy 1, Get 2 FREE*Optimal Multivitamin Powder - 30 Servings
4.5Rated 4.5 out of 581 Reviews Based on 81 reviewsFrom $47.95Optimal Multivitamin Powder by Seeking Health provides bioavailable nutrients in easy-to-absorb forms such as methylfolate and active B12, and mine...
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Buy 1, Get 2 FREE*Optimal Multivitamin Chewable - 60 Tablets
4.7Rated 4.7 out of 5319 Reviews Based on 319 reviewsFrom $29.95Optimal Multivitamin Chewable by Seeking Health provides a wide variety of nutrients in well-absorbed or active forms in a great-tasting chewable t...
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Buy 1, Get 2 FREE*Optimal Multivitamin - 240 Capsules
4.9Rated 4.9 out of 5237 Reviews Based on 237 reviewsFrom $59.95Optimal Multivitamin by Seeking Health is a complete daily multivitamin and mineral supplement containing more than 50 nutritional ingredients, all...
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Bonus RewardsMultivitamin with Iron - 120 Capsules
4.8Rated 4.8 out of 581 Reviews Based on 81 reviewsFrom $32.95Multivitamin with Iron by Seeking Health is a well-rounded daily multivitamin and mineral supplement with high-potency gentle iron and active B vit...
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Best SellerOptimal Prenatal - 240 Capsules
4.8Rated 4.8 out of 5687 Reviews Based on 687 reviewsFrom $59.95Optimal Prenatal capsules by Seeking Health provide a comprehensive prenatal formula with a unique blend of amino acids, chelated minerals, and vit...
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L-5-MTHF Lozenge - 60 Lozenges
4.8Rated 4.8 out of 579 Reviews Based on 79 reviewsFrom $18.95L-5-MTHF Lozenges by Seeking Health provide 1,700 mcg DFE (1,000 mcg) of pure non-racemic l-methylfolate, a coenzyme form of folate, in a naturally...
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L-5-MTHF (1700 mcg DFE) - 60 Capsules
4.9Rated 4.9 out of 568 Reviews Based on 68 reviewsFrom $17.95L-5-MTHF Capsules by Seeking Health provide 1,700 mcg DFE (1,000 mcg) of pure non-racemic L-methylfolate, an active coenzyme form of folate. Folate...
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Kids Multivitamin - 180 Capsules
4.8Rated 4.8 out of 5147 Reviews Based on 147 reviewsFrom $32.95Kids Multivitamin by Seeking Health is a comprehensive multivitamin and mineral supplement that is specifically designed to support the nutritional...
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Best SellerHomocysteX Plus - 60 Capsules
4.9Rated 4.9 out of 5191 Reviews Based on 191 reviewsFrom $32.95HomocysteX Plus by Seeking Health supplies bioactive forms of four essential B-vitamins together with betaine (also known as trimethylglycine or TM...
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Best SellerBonus RewardsB Complex Plus - 100 Capsules
4.9Rated 4.9 out of 5249 Reviews Based on 249 reviewsFrom $27.95B Complex Plus by Seeking Health provides eight B vitamins with active forms of folate, vitamin B12, riboflavin, and B6. This complex also contains...
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Best SellerActive B12 with L-5-MTHF - 60 Lozenges
4.9Rated 4.9 out of 5498 Reviews Based on 498 reviewsFrom $21.95Active B12 with L-5-MTHF Lozenges by Seeking Health provide 1,360 mcg DFE (800 mcg) of pure non-racemic L-methylfolate in an easy-to deliver lozeng...
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