Skip to content
L-Methylfolate
5 Stars
Wow!

I have no idea why I waited so long in life to use this stuff. I’m so much calmer and life feels so much easier. It’s made such a beautiful difference.†~Cindy K.

L-Methylfolate

$20 - $120
$60
$20
$20.00 - $102.00
$20

Key Benefits:†

  • Powerful methylation, MTHFR, and homocysteine support
  • Supports healthy cognition and mood
  • Healthy genetic expression support
Purchase Type
graphic of vile

Third Party Tested

graphic of delivery truck

Free Shipping

graphic of check mark

60-day Return Policy

Graphic of capsule being opened

High End Ingredients

Description of the image
Wow!

I have no idea why I waited so long in life to use this stuff. I’m so much calmer and life feels so much easier. It’s made such a beautiful difference.†~Cindy K.

Methylation controls multiple biochemical pathways in your body.

Your genetics, heart health, hormones, sleep, stress, mood, and detoxification depend on healthy methylation.

Where does your body get the methyl groups needed to carry out methylation? Primarily from folates that come from food and intestinal microbes. Food folates must be first converted into an active form before your body can use them.

Your MTHFR enzyme converts food folates into the active form of folate, methylfolate. This bioavailable form is also known as L-methylfolate. The true biochemical name is L-5-methyltetrahydrofolate (L-5-MTHF).

Over 50 percent of the population is thought to have a genetic mutation in their MTHFR gene. Thus, they may not be achieving adequate methylfolate levels from food alone.

Because L-5-MTHF bypasses the MTHFR enzyme, it can provide methylation support for those with MTHFR polymorphisms.†

Folate (as bioavailable L-methylfolate) is:†

  • Easily absorbed and used by cells
  • The predominant form of folate in circulation
  • The only form of folate that can cross the blood-brain barrier
  • Essential for methylation, DNA expression, homocysteine metabolism, and nervous system function

Seeking Health’s L-methylfolate contains 1,700 mcg DFE of methylfolate in the bioavailable form of L-5-methyltetrahydrofolate (L-5-MTHF).†

The bioactive form of L-methylfolate (L-5-MTHF) is well-utilized in the methylation cycle. It is often the preferred form for those with methylation, homocysteine, or MTHFR gene mutation concerns.†

Mutations in your MTHFR gene can lead to reduced L-methylfolate production and a less functional methylation cycle. Challenges in the methylation cycle are associated with an increased risk for cardiovascular and mood issues, birth defects, and infertility concerns.

Mutations in this gene can also slow your body’s ability to convert folate into its active forms. Thus, a large majority of people may benefit from consuming an L-methylfolate dietary supplement.†

The most direct way to support methylation and MTHFR genetic mutations is with L-methylfolate (L-5-MTHF).†

Supplementing with bioavailable L-methylfolate supports:†

  • Healthy methylation
  • Positive mood
  • Healthy homocysteine levels
  • Nervous system function and development
  • Prevention of neural tube defects during pregnancy
  • Healthy energy production
  • Normal cognitive, memory, and brain function

Get ready for your methylation cycle to fire on all cylinders with Seeking Health’s L-methylfolate!†

Key Ingredients

Inside the Uncompromising Quality of Our Ingredients

View Supplements Label
×
  • L-5-MTHF
    A superior form of L-methylfolate that readily donates its methyl groups. It aids conversion of the amino acid homocysteine into methionine and supports your entire methylation cycle.†

Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under US Patent 7,947,662.

Suggested Use

As needed, take 1 capsule with or without food. Do not take within 5 hours of bedtime as it may interfere with sleep. Use as directed by your healthcare professional.

Suitable for

Bariatric, pregnancy, breastfeeding, vegetarian, vegan, ages 4 and up

Delivery Method

Capsules

Age Suitability

Adults, ages 4 and up

How to Store

Keep closed in a cool, dry place out of reach by children.

What our customers say

Real reviews from real customers.

4.8
Rated 4.8 out of 5 stars
Based on 107 reviews
Total 5 star reviews: 93 Total 4 star reviews: 9 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 3
95%would recommend these products
Customers Talked About
Search
Search Reviews
Rating
Ratings
Write a Review (Opens in a new window)
107 reviews
  • E
    Elle
    Verified Reviewer
    Reviewing
    L-Methylfolate
    I recommend this product
    Rated 5 out of 5 stars
    4 weeks ago
    L-Methylfolate

    ❤️

    Was this helpful?
  • EB
    Emily B.
    Verified Buyer
    Reviewing
    L-Methylfolate
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    52 yrs + didn’t know I can’t absorb folate from food!

    Game changer! I recently had my functional genomics run through Kash Kahn/The DNA Company and discovered to my dismay that I cannot and will never be able to absorb folate from food. I need a very specific supplemental form of it. Thank you Seeking Health for making it so easy for me to start repairing deficiency.!

    Was this helpful?
  • ME Profile picture for Miranda E.google logo
    Miranda E.
    Verified Buyer
    Reviewing
    L-Methylfolate
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Great

    I could tell an immediate difference once taking this supplement in my energy levels. It is definitely a product I am going to continue to use.

    Was this helpful?
Show More

Stay up to date on our latest product releases, events, and more!

Receive 10% off your order when you download our App!