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Optimal GI

SALE $47.95
  • Targeted herb and nutrient blend supports gut health
  • Supports healthy digestion and bowel motility
  • Free from L-glutamine

Who Needs Optimal GI

Your gut health sets the stage for your overall health. Ensuring healthy digestion and absorption of nutrients is also one of the most powerful things you can do for your immune function.

Optimal GI provides a blend of herbs and nutrients that synergistically support healthy digestion, GI barrier, and immune system function.

Optimal GI was formulated by epigenetics expert Dr. Ben Lynch. This unique formula supports digestive tract function with a powerful blend of nutrients along with soothing and strengthening herbs.

Optimal GI supports the following health benefits:

  • An effective gut barrier
  • Normal intestinal motility
  • Digestive health and comfort
  • Healthy connective tissues in the GI tract
  • Healthy mucous membranes in the GI tract
  • Regular bowel movements and waste elimination
  • Healthy detoxification pathways
  • A healthy gut microbiome

An unhealthy gut can contribute to digestive issues such as bloating, constipation, diarrhea, and malabsorption. Moreover, many diseases of modern society are thought to be rooted in a leaky gut.

If intestinal barrier function becomes compromised, it can trigger the ongoing activation of the immune system and inflammation. With over 60% of the immune system located in the gut lining, a healthy digestive system is also critical for immune health.

The gastrointestinal (GI) tract requires more than probiotics to support healthy digestion.

Optimal GI contains traditional herbs, including marshmallow root, licorice extract (DGL), milk thistle, cat’s claw, aloe vera, turmeric, and slippery elm. It also contains targeted nutrients like N-Acetyl-D-Glucosamine and MSM that support gut lining health and function.

Each serving of Optimal GI provides 500 mg of citrus pectin. This natural fiber provides bulk to support healthy bowel movements. It promotes regular detoxification by binding to toxins. This formula is gluten-free and free of GMO-markers.

Optimal GI is free from L-glutamine for those who do not tolerate it. The convenient capsules provide a lower strength than our best-selling Optimal GI Plus powder.

If you're ready to optimize your digestive and gastrointestinal wellness, talk to your healthcare team about Optimal GI.

Customer Review

I can not say enough good things about this product!

My family has been using optimal GI for a year or more. I can’t believe what a difference it has made, especially my husband. He has numerous health issues, but this product has provided breakthrough, no pun intended. 😊 ~Nancy H.

Key Ingredients In Optimal GI

  • Citrus Fiber: A natural fruit fiber that provides bulk to support healthy bowel movements. It also supports regular detoxification by binding to toxins.
  • Slippery Elm: A traditional herb that supports a healthy mucosal lining in the GI tract.
  • Zinc L-Carnosine: Supports gut lining integrity and stomach comfort.
  • Cat’s Claw & Turmeric Extract: Support healthy inflammatory processes in the intestinal lining.
  • N-Acetyl-D-Glucosamine: Supports a healthy mucosal layer in the GI tract.

Why Optimal GI Works

The gastrointestinal (GI) tract has been called the “inner tube” of life. Running from your mouth to down south, this tube spans up to 30 feet in length with a surface area nearing that of a tennis court! This large surface area allows for the primary function of the GI tract: to absorb nutrients from food while preventing toxins and microbes from entering your bloodstream.

The lining of the GI tract is very thin. It’s only one single cell layer thick. This allows the intestinal wall to act as a selective barrier, permitting certain substances to enter the body (e.g. digested food particles) while excluding others (e.g. harmful bacteria). This single layer of cells constitutes the most critical physical barrier that separates your bloodstream from the milieu of toxins constantly traveling through your digestive system.

The cells constituting the gut wall are arranged side-by-side and connected by microscopic gates called tight junctions. If the gut wall’s barrier function breaks down, the tight junctions can become damaged, and the intestinal lining can become leaky. This condition is known as increased intestinal permeability (hyperpermeability) or leaky gut syndrome.

Many factors can compromise the integrity of the gut lining.

  • Poor diet
  • Unhealthy gut flora (disproportionate ratio of good bacteria to bad bacteria)
  • Lack of fermented foods and probiotics in the diet
  • Autoimmune diseases
  • Gluten consumption
  • Food sensitivities

A leaky gut allows for undigested foods, toxins, and pathogens to leak into your bloodstream. Left unchecked, it can trigger the ongoing production of inflammation. This is because the majority of your immune system (over 60%) resides within your gut wall. A primary function of your immune system is to produce inflammatory chemicals in response to anything it deems foreign. Most diseases of modern society are characterized by excess inflammation. This is why many healthcare experts claim that both health and disease begin in the gut.

When we eat sharp foods like chips or anchovy bones, our intestinal cells can become damaged. As a result, our bodies expend tremendous energy replacing and repairing the gut lining every few days. Some estimate that up to 20 percent of the energy from the food we eat goes toward this process!

Thankfully, our intestinal cells produce mucus as a layer of protection. This mucosal lining is critical for overall gut health.

The ability of your intestinal lining to produce the protective mucus layer is dependent on the food you eat, and in particular, fiber. Unfortunately, many people struggle to make enough mucus in their intestines due to modern diets and lifestyles. Inadequate mucus production can impair your ability to protect your intestines from harmful microbes, parasites, and toxins.

Optimal GI contains traditional herbs and targeted nutrients that support gut lining health and function. It includes the following gut-supportive ingredients:

  • Gut lining support: Zinc supports the rapid cell turnover which occurs during gut lining repair. It also supports normal protection of the gut lining and natural defenses against gut bacteria. N-Acetyl-D-Glucosamine supports healthy GI barrier function and the body’s normal defense responses against pathogenic bacteria.
  • Demulcent herbs: Mucus-producing herbs stimulate natural mucosal production in the GI tract. They also soothe the intestinal tract and support its natural protective mechanisms. These include aloe vera, deglycyrrhizinated licorice root extract (DGL), marshmallow root, and slippery elm.
  • Fiber: A lack of dietary fiber has been shown to decrease the production of mucins from mucosal cells. Citrus fiber is included to support bowel regularity and normal detoxification pathways by binding to toxins.
  • Healthy inflammation & immune support: Cat’s claw, MSM, aloe vera, and turmeric support healthy inflammatory and immune responses in the GI tract.
  • Histamine support: The intestinal lining is responsible for secreting DAO. Diamine Oxidase (DAO) is the primary enzyme responsible for breaking down histamine in your gut. An unhealthy intestinal lining can lead to low levels of DAO and subsequent struggles with histamine intolerance. Optimal GI also includes herbs that help support a healthy histamine response, including stinging nettle and quercetin.
  • Antioxidant support: Superoxide Dismutase (SOD), turmeric, and glucoraphanin support antioxidant activity and oxidative stress levels by promoting normal detoxification pathways.
  • GI barrier support: Nutrients that support gut lining integrity include N-Acetyl D-Glucosamine and MSM.

Optimal GI is free from L-glutamine for those who do not tolerate it. Consider our Optimal GI Plus if you’re looking for stronger formula, a powder form, or the same great formula with added L-glutamine.

Optimal GI
Supplement Facts

Serving Size: 5 Capsules
Servings Per Container: 30

Calories 5
Total Carbohydrate 1 g <1%
Dietary Fiber 1 g 4%
Zinc (as Zinc L-Carnosine) 10.5 mg 95%
Molybdenum (as Molybdenum Glycinate Chelate)(Albion®) 35 mcg 78%
N-Acetyl-D-Glucosamine 500 mg **
Grapefruit Whole Fruit Pectin 500 mg **
Deglycyrrhizinated Licorice Extract (Glycyrrhiza glabra)(root)(3% glycyrrhiznic acid 7.5mg) 250 mg **
Aloe Vera 200:1 Extract (Aloe barbadensis)(leaf gel) 175 mg **
Cat's Claw Extract (Uncaria tomentosa)(bark) 175 mg **
Turmeric Extract (Curcuma longa)(rhizome)(95% curcuminoids 118mg) 125 mg **
Stinging Nettle Extract (Urtica dioica)(Leaf Extract)(1% silica 1mg) 125 mg **
Slippery Elm (Ulmus fulva)(bark) 125 mg **
Quercetin (as quercetin dihydrate from Saphora japonica) 125 mg **
Methylsulfonylmethane (MSM) 125 mg **
Marshmallow (Althaea officinalis)(root) 100 mg **
L-Carnosine (from Zinc L-Carnosine) 41 mg **
Milk Thistle Extract (Silybum marianum)(seeds)(80% silymarin 20mg) 25 mg **
Glucoraphanin (from broccoli extract)(Brassica oleracea)(seed)(TrueBroc®) 9 mg **
Extramel® Superoxide Dismutase [from melon (Cucumis melo)(pulp) extract] 3.5 mg (49 IU) **
Percent Daily Values are based on a 2,000 calorie diet.
**Daily Value (DV) not established.

Other Ingredients: Vegetarian capsule (hypromellose and water), microcrystalline cellulose, ascorbyl palmitate, and silica.
Albion® is a registered trademark of Balchem Corporation or its subsidiaries
TrueBroc® is protected by trademarks and patents of Brassica Protection Products LLC

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Capsules
  • How To Store: Keep closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use Optimal GI

Suggested Use

Optimal GI should be taken away from food. Take 5 capsules daily, away from food, in divided doses, or as directed by your healthcare professional.


Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Consult with a healthcare professional before use if you are undergoing treatment for any medical condition or if you are using any medication(s), including NSAIDs.

FAQs for Optimal GI

What is the purpose of each ingredient in Optimal GI?

Ingredients Purpose
Zinc L-Carnosine Supports normal protection of the small intestinal lining and a normal response to bacteria in the stomach lining
Molybdenum Supports the healthy conversion of sulfites to sulfate, metabolism of hydrogen sulfide, and the metabolism of sulfur from sulfur-containing nutrients found in this product
N-Acetyl D-Glucosamine Supports a healthy and normal response to pathogenic bacteria; Supports healthy GI barrier function
Citrus Fiber Supports bowel regularity and normal detoxification
Deglycyrrhizinated Licorice Extract (DGL) Help soothe and calm tissues
Aloe Vera & Slippery Elm Help soothe and calm tissues
Marshmallow root Help soothe and calm tissues
Cat's Claw Extract Supports healthy inflammatory responses in the GI tract
Turmeric Extract (Curcuminoids) Supports healthy inflammatory responses and immune system activity
Stinging Nettle Extract Supports normal histamine release
Quercetin Supports normal histamine release
Methylsulfonylmethane (MSM) Provides sulfur to local connective tissues in gut lining; Supports healthy inflammatory responses
Milk Thistle Extract Supports the liver; Plays a role in processing compounds produced by GI inflammation and unhealthy microbes
Glucoraphanin (from broccoli seed extract) Supports normal metabolism of environmental pollutants, and reactive oxygen species, such as hydrogen peroxide and superoxide
Superoxide Dismutase (SOD) Supports antioxidant activity and the body’s healthy response to oxidative stress

Who is Optimal GI intended for?

Optimal GI is intended for those seeking to support the health of their gut lining, stomach, and intestinal function without the use of L-glutamine (for those who are sensitive to L-glutamine).

While L-glutamine is an important aspect of gut health, it is not well-tolerated by some individuals. This product may be taken at night, whereas Optimal GI Plus powder (with L-glutamine) should not be taken at night. L-glutamine may increase sleeplessness due to increasing L-glutamate in the brain. Optimal GI is in capsule form versus a powder, making it easier to take for those who do not prefer the taste of Optimal GI Plus powder.

Optimal GI contains citrus fiber. Is it okay to take if I have histamine sensitivity?

Citrus fiber is different than citrus itself. The fiber is not known to contain or liberate histamine.

Histamine intolerance and sensitivity can vary person-to-person. Therefore, foods that are okay for some are not okay for others. As always, talk to your qualified healthcare provider to determine if this product is right for you.

If you have a question that's not addressed
here, see all frequently asked questions.


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What our customers say

Real reviews from real customers.

Rated 4.8 out of 5 stars
Based on 102 reviews
Total 5 star reviews: 88 Total 4 star reviews: 7 Total 3 star reviews: 7 Total 2 star reviews: 0 Total 1 star reviews: 0
92%would recommend these products
102 reviews
  • LM
    Lynnet M.
    Verified Buyer
    Optimal GI
    Optimal GI
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    Supporting my gut

    Optimal GI is one of my favorite products since I need support for a sensitive gut. Taking it away from food is how I know it is supportive, feels soothing. Hope you'll try it and find it soothing for you.

  • SZ
    Stephanie Z.
    Verified Buyer
    Optimal GI
    Optimal GI
    I recommend this product
    Rated 5 out of 5 stars
    5 months ago
    Love this Product!

    I bought this for two of my daughters and both have remarked positively. They both have had many digestive issues and this product has been a lifesaver! Thank you Seeking Health (Dr. Ben Lynch)!

  • R
    Verified Buyer
    Optimal GI
    Optimal GI
    I recommend this product
    Rated 5 out of 5 stars
    6 months ago
    Ootimal GI

    This supplement has been a game changer for my gut health. Will always have it on hand!

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