TL;DR Detoxification is your body’s natural way of removing harmful substances, mainly through the liver and kidneys. To support this process, focus on hydration, a healthy diet, and exercise. Certain nutrients, including B vitamins, glutathione, and magnesium, are vital in detoxification. These nutrients help support chemical breakdown, cell health, and your body’s ability to flush out waste and are available from Seeking Health™. While no quick fix or fad diet can instantly detox your system, supplementing with these nutrients supports your body’s natural detox pathways and overall health.†
What Is Detoxification?

Detoxification is the process by which your body gets rid of harmful substances. It eliminates chemicals through different mechanisms and organs, depending on the properties of each substance.
This process is primarily carried out by the liver. The kidneys help remove chemicals or their byproducts through urine, while others are expelled through stool, sweat, or even breath.
How Does Your Body Detox?
The liver is responsible for the biotransformation of chemicals into less harmful forms, making them water-soluble, which makes it possible for the kidneys to excrete them afterward. This is true for both naturally occurring and man-made chemicals.
There are two main steps in liver detoxification:
Phase 1: Breaking Down Chemicals
- During this phase, your liver works to break down harmful substances. These chemicals can come from things like pollution, alcohol, or even natural reactions in your body.
- However, this process can sometimes create harmful byproducts known as free radicals, which can damage your cells. Antioxidants play a key role here by stopping these byproducts from causing harm.
Phase 2: Neutralizing and Getting Rid of Chemicals
- After Phase 1, your liver processes the broken-down chemicals further by connecting them to molecules like glutathione. This process, called conjugation, makes chemicals safer and easier for your body to handle.
- Finally, these now water-soluble chemicals are sent out of your body through urine or bile, completing their safe removal.
Remember, your liver is always working hard to keep you healthy by getting rid of chemicals this way!
However, it needs the right mix of nutrients to work well. Eating plenty of fruits and vegetables, drinking enough water, and staying active can help your body stay clean and healthy.
Some problems, like fatty liver disease and gallbladder dysfunction, can make it hard for your liver to do its job. It's important to check your liver’s health with your healthcare practitioner if you feel any related symptoms, such as constant fatigue, intolerance to fatty foods, insomnia, digestive issues, and a yellow tint of the cornea.
What Are the 7 Most Important Detoxification Support Supplements?†
The top seven most essential nutrients and substances for supporting your body's processes are:
-
Glutathione (GSH)
Acting as the body's master antioxidant, glutathione is crucial for detoxification. It plays a central role in supporting the body's healthy defense against oxidative stress and is a key component of phase II detoxification in the liver.1† -
Choline
Choline plays an important role in the liver's natural protective mechanisms by supporting bile production and flow, as well as healthy fat metabolism.2† -
B Vitamins
This group of vitamins, particularly B2, B6, B12, and folate, is essential for supporting healthy methylation processes, which are critical for detoxification. They also support the liver's ability to process and eliminate chemicals efficiently.3† -
Zinc
This mineral is vital for supporting over 300 healthy enzymatic reactions in your body, many related to detoxification processes. Zinc deficiency can impair the liver's ability to metabolize alcohol and other chemicals.4† -
Omega-3
Omega-3s support a healthy inflammatory response, the liver’s natural protective mechanisms, and support overall health by being a key part of cell membranes.5† -
Selenium
Selenium is an important nutrient that supports the liver’s natural protective mechanisms. It is needed for the function of antioxidant enzymes, like glutathione, which support a healthy response to oxidative stress.6† -
Magnesium
This mineral is involved in over 600 normal enzymatic reactions in your body, including those related to detoxification. It supports healthy glutathione production and helps support your body's healthy stress response, which can impact detoxification processes.7†
These work synergistically to support the body's natural detoxification processes, particularly in the liver.†
How Your Genes Impact Detoxification
Taking care of your health means truly understanding your unique needs. What works for someone else might not be the right fit for you.
Your genes and lifestyle shape your health journey in a deeply personal way. Genetic differences, in particular, can influence how your body detoxifies, making it more challenging for some people than others.
For example, if you have a genetic predisposition that affects bile flow, such as a Dirty PEMT gene, you face a higher risk for fatty liver and Small Intestinal Bacterial Overgrowth (SIBO).8
These conditions can make detoxing harder, as fatty liver reduces the body’s ability to eliminate harmful chemicals, and SIBO can interfere with digestion and nutrient absorption, further complicating the detox process.
Download our free Gallbladder Guide and Digestion Guide to discover simple, effective ways to support these organs for optimal detoxification.
Effective Ways to Support Detoxification

Here's a simple plan to help your body detox:
- Work on supporting your metabolic flexibility – it can really help your body detox by supporting your metabolism, so it can efficiently help your body eliminate any chemicals you come across.
- Give saunas a try, as they support detoxification. Just make sure you're doing it the right way. Download our free sauna guide to learn how. Don’t have one? A hot bath or steamy shower with the door closed can give you some of the same benefits, like relaxation and sweating.
- Aim for at least one well-formed bowel movement a day with a mild odor, as this is a sign of healthy digestion and effective detoxification.
- Avoid exposure to environmental chemicals such as mold, toxins, pollutants, and heavy metals. To help with this, consider using an air purifier to improve indoor air quality and filter your water to reduce contaminants. Remember: if you aren’t filtering your water, then YOU are the filter!
- Address any nutritional deficiencies to support liver detoxification phases
- Drink plenty of water to help flush out chemicals through urine.
- Get regular exercise to promote sweating and support circulation.
- Include foods rich in D-glucaric acid, like apples and broccoli, which may help support detoxification.
- Consider adding spices like garlic, ginger, turmeric, and cardamom to your meals, as they may support detoxification.9
- Include detoxification-supporting supplements like those you read about earlier in your daily diet.†
- Avoid processed foods and reduce your intake of sugar and unhealthy fats.
- Sleep well enough to allow your body time to repair and detoxify.10
Remember, it's always best to consult your healthcare professional before starting any new health plan.
Detoxification Support Supplements by Seeking Health™†
Give your liver a hand and help support its health and critical body detoxification process with supplements by Seeking Health™! They are scientifically formulated with top-notch ingredients to support your body's ability to break down chemicals, medications, heavy metals, and other harmful compounds harmful to your well-being. Believe in Better and support your body for long-term health and well-being!†

Glutathione Plus includes triple glutathione support, including Emothion® S-Acetyl-L-Glutathione, a trademarked form of glutathione researched to be more stable than other types due to its unique formulation. It supports healthy lungs, skin, eyes, and immune system function.†
Liver Nutrients is an all-in-one liver support dietary supplement. This synergistic blend of nutrients and herbs supports the healthy metabolism of chemicals and hormones in the liver. This formula also promotes normal glutathione production and liver cell regeneration.†
Zinc Lozenge is a chewable dietary supplement containing a gentle, well-tolerated form of zinc. It supports healthy antioxidant enzyme activity, immune system function, eyes, hair, skin, and intestinal lining. It tastes great, too!†
B Complex Plus includes 680 mcg DFE (400 mcg) of the active, methylated form of folate. Active folate is known as 5-methyltetrahydrofolate (5-MTHF). It is the only form of folate that crosses the blood-brain barrier. It supports MTHFR gene variations and healthy methylation throughout your body.†

Magnesium Plus is ideal for those seeking magnesium health benefits from two superior types of magnesium plus vitamin B6 for optimal absorption. Each capsule serving provides 125 mg of elemental magnesium in the glycinate and malate forms plus 30 mg of P-5-P, the active coenzyme form of vitamin B6.†
Optimal Electrolyte supports healthy hydration, heart rhythm, contraction, and virtually every bodily function and organ. According to Dr. Lynch, “Proper hydration is second to breathing in terms of importance to sustain a healthy life.” Simply mix your favorite flavor (or unflavored) with water to take with you and sip throughout the day. Optimal Electrolyte also comes in single-serving sticks for convenience on the go!†

Ox Bile provides 125 mg of pure bile from free-range oxen (bovine). It contains 40% cholic acid for efficient and targeted fat digestion support. Consuming Ox Bile with high-fat meals may lessen your body’s demand for bile. This can lead to lower stress on your liver and gallbladder while supporting the breakdown of dietary fat. Proper fat breakdown is critical for the absorption of fat-soluble vitamins and essential fatty acids from foods.†
A single softgel of Fish Oil provides nearly one gram of omega-3 fatty acids in natural triglyceride form, sourced from Norwegian cold water fish. Fish Oil includes eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These important omega-3 fatty acids have many health benefits, including helping support normal inflammatory responses.†
The Bottom Line

Thanks to organs like your liver and kidneys, your body is equipped with an incredible detoxification system. However, you need to support it with the proper nutrients and healthy habits, or it won’t work properly. Supplements containing B vitamins, glutathione, magnesium, vitamin E, and zinc are essential for your body’s natural detox pathways, supporting effective chemical removal. While no magic solution exists for instant detoxification, staying hydrated, eating a balanced diet, and regularly exercising are simple ways to support your overall health and your body’s natural ability to cleanse. And remember, Seeking Health™ is here to help with its diverse line of high-quality, science-backed detoxification support supplements!†
References:
- https://pubmed.ncbi.nlm.nih.gov/37432335/
- https://pubmed.ncbi.nlm.nih.gov/23493015/
- https://pubmed.ncbi.nlm.nih.gov/23493015/
- https://pubmed.ncbi.nlm.nih.gov/31165884/
- https://pubmed.ncbi.nlm.nih.gov/37538264/
- https://pubmed.ncbi.nlm.nih.gov/22381456/
- https://pubmed.ncbi.nlm.nih.gov/16772543/
- https://pubmed.ncbi.nlm.nih.gov/37191416/
- https://pubmed.ncbi.nlm.nih.gov/23075940/
- https://pubmed.ncbi.nlm.nih.gov/26167297/
† These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.