COMT Slow Support - Dirty Genes®
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
SHOP NOW $234.8Rated 4.8 out of 5 stars140 ReviewsFrom $23Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars159 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
ImprovedOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00Save 67%$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars223 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
SHOP NOW $274.9Rated 4.9 out of 5 stars307 ReviewsFrom $27Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full detailsOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerHSA / FSAOptimal Electrolyte
SHOP NOW $404.6Rated 4.6 out of 5 stars1,680 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Coming SoonEstrogen Nutrients
From $45For women experiencing occasional bloating, breast tenderness, mood shifts, and menstrual discomfort associated with PMS and their monthly cycle, ...
View full detailsOriginal price $45 - Original price $243Original priceSALE$45.00 - $243.00$45.00 - $243.00Original price $45.00 - Original price $243.00Original price$45.00 - $243.00$45.00 - $243.00Current price $45$45.00 - $243.00Current price $45
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Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
SHOP NOW $234.8Rated 4.8 out of 5 stars140 ReviewsFrom $23Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars159 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
ImprovedOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00Save 67%$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars223 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
SHOP NOW $274.9Rated 4.9 out of 5 stars307 ReviewsFrom $27Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full detailsOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerHSA / FSAOptimal Electrolyte
SHOP NOW $404.6Rated 4.6 out of 5 stars1,680 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Coming SoonEstrogen Nutrients
From $45For women experiencing occasional bloating, breast tenderness, mood shifts, and menstrual discomfort associated with PMS and their monthly cycle, ...
View full detailsOriginal price $45 - Original price $243Original priceSALE$45.00 - $243.00$45.00 - $243.00Original price $45.00 - Original price $243.00Original price$45.00 - $243.00$45.00 - $243.00Current price $45$45.00 - $243.00Current price $45
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Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Magnesium Malate Chewable
SHOP NOW $234.8Rated 4.8 out of 5 stars140 ReviewsFrom $23Key Benefits and Actions† Delicious chewable magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, ner...
View full detailsOriginal price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.†
Best SellerOptimal Electrolyte Sticks
SHOP NOW $404.7Rated 4.7 out of 5 stars159 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Feed your brain by supporting healthy mental energy, mood, concentration, and focus with Brain Nutrients.†
Brain Nutrients—Designed to support a healthy, thriving brain with a unique blend of nutrients, including Emothion™ S-Acetyl-L-Glutathione, PeakATP®, and LifePQQ™.†
ImprovedOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00Save 67%$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars223 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerHydroxo B12 with Folinic Acid
SHOP NOW $274.9Rated 4.9 out of 5 stars307 ReviewsFrom $27Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...
View full detailsOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerHSA / FSAOptimal Electrolyte
SHOP NOW $404.6Rated 4.6 out of 5 stars1,680 ReviewsFrom $40Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00Save 67%$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Coming SoonEstrogen Nutrients
From $45For women experiencing occasional bloating, breast tenderness, mood shifts, and menstrual discomfort associated with PMS and their monthly cycle, ...
View full detailsOriginal price $45 - Original price $243Original priceSALE$45.00 - $243.00$45.00 - $243.00Original price $45.00 - Original price $243.00Original price$45.00 - $243.00$45.00 - $243.00Current price $45$45.00 - $243.00Current price $45
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