COMT Slow Support - Dirty Genes®
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
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Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
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Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
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Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
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Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
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Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
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Foster healthy energy production and mood with methyl-free B Complex MF.†
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Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
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Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
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Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
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Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
Lithium Orotate—Provides a low serving of lithium (5 mg per capsule) as lithium orotate attached to the natural compound orotic acid for optimal bioavailability and efficient absorption.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerHSA / FSAOriginal price $42 - Original price $252Original price $42 - Original price $252Original price $126$126$42.00 - $214.20Save 67%$42.00 - $214.20Original price $42.00 - Original price $252.00Original price $42.00 - Original price $252.00Original price $126.00$42.00 - $214.20$42.00 - $214.20Current price $42$42.00 - $214.20Current price $42 -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
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HSA / FSAOriginal price $37 - Original price $222Original price $37 - Original price $222Original price $111$111$37.00 - $188.70Save 67%$37.00 - $188.70Original price $37.00 - Original price $222.00Original price $37.00 - Original price $222.00Original price $111.00$37.00 - $188.70$37.00 - $188.70Current price $37$37.00 - $188.70Current price $37 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
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Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Promote healthy energy production and mood without additional B12 and folate with B Minus.†
B Minus—A potent formula containing 6 essential B vitamins that’s free from B12 and folate to allow for customization of these two essential nutrients.†
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Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Best SellerHSA / FSAOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20Save 67%$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Foster healthy energy production and mood with methyl-free B Complex MF.†
B Complex MF—A potent B vitamin complex containing the 8 essential B vitamins, featuring non-methylated B12 and folate in the forms of Hydroxo B12 and folinic acid.†
Original price $32 - Original price $192Original price $32 - Original price $192Original price $96$96$32.00 - $163.20Save 67%$32.00 - $163.20Original price $32.00 - Original price $192.00Original price $32.00 - Original price $192.00Original price $96.00$32.00 - $163.20$32.00 - $163.20Current price $32$32.00 - $163.20Current price $32 -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Original price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80Save 67%$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Original price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
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Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.†
Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).†
Original price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50Save 67%$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Nurture your emotional well-being and mood balance to cope well during times of high stress, worry, and anger with Lithium Orotate!†
Lithium Orotate—Provides a low serving of lithium (5 mg per capsule) as lithium orotate attached to the natural compound orotic acid for optimal bioavailability and efficient absorption.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Be kind to your gut while supporting its health with the low-histamine formula of ProBiota™ HistaminX™!†
ProBiota™ HistaminX™—A unique probiotic supplement designed specifically for those sensitive to histamine that contains histamine-friendly probiotics in an acid-resistant capsule.†
Best SellerHSA / FSAOriginal price $42 - Original price $252Original price $42 - Original price $252Original price $126$126$42.00 - $214.20Save 67%$42.00 - $214.20Original price $42.00 - Original price $252.00Original price $42.00 - Original price $252.00Original price $126.00$42.00 - $214.20$42.00 - $214.20Current price $42$42.00 - $214.20Current price $42 -
Give your body the methyl-free support it needs while still getting your daily dose of vitamins with Multivitamin One MF.†
Multivitamin One MF—A one-a-day multivitamin containing many essential daily nutrients in methyl-free forms, delivered in a well-absorbed capsule without vitamin C, magnesium, calcium, or iron to allow customization.†
HSA / FSAOriginal price $37 - Original price $222Original price $37 - Original price $222Original price $111$111$37.00 - $188.70Save 67%$37.00 - $188.70Original price $37.00 - Original price $222.00Original price $37.00 - Original price $222.00Original price $111.00$37.00 - $188.70$37.00 - $188.70Current price $37$37.00 - $188.70Current price $37 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
ImprovedHSA / FSAOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00Save 67%$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Get the magnesium support you need for healthy energy, muscles, nerves, and feelings of calm from Magnesium Malate Chewable!†
Magnesium Malate Chewable—Provides 100 mg of well-tolerated dimagnesium malate per tasty, chewable tablet for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
Promote healthy energy production and mood without additional B12 and folate with B Minus.†
B Minus—A potent formula containing 6 essential B vitamins that’s free from B12 and folate to allow for customization of these two essential nutrients.†
Original price $32 - Original price $192Original price $32 - Original price $192Original price $96$96$32.00 - $163.20Save 67%$32.00 - $163.20Original price $32.00 - Original price $192.00Original price $32.00 - Original price $192.00Original price $96.00$32.00 - $163.20$32.00 - $163.20Current price $32$32.00 - $163.20Current price $32 -
Nurture the support of GI comfort, relaxation, and natural energy production with the gentle blend of nutrients found in Optimal Magnesium.†
Optimal Magnesium—Provides two well-tolerated forms of bioavailable magnesium (malate and lysinate-glycinate) in one simple capsule to support natural energy, relaxation, and GI comfort.†
Best SellerHSA / FSAOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20Save 67%$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22 -
Foster healthy energy production and mood with methyl-free B Complex MF.†
B Complex MF—A potent B vitamin complex containing the 8 essential B vitamins, featuring non-methylated B12 and folate in the forms of Hydroxo B12 and folinic acid.†
Original price $32 - Original price $192Original price $32 - Original price $192Original price $96$96$32.00 - $163.20Save 67%$32.00 - $163.20Original price $32.00 - Original price $192.00Original price $32.00 - Original price $192.00Original price $96.00$32.00 - $163.20$32.00 - $163.20Current price $32$32.00 - $163.20Current price $32 -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
Original price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80Save 67%$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Original price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00Save 67%$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!†
Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.†
Best SellerOriginal price $27 - Original price $162Original price $27 - Original price $162Original price $81$81$27.00 - $137.70Save 67%$27.00 - $137.70Original price $27.00 - Original price $162.00Original price $27.00 - Original price $162.00Original price $81.00$27.00 - $137.70$27.00 - $137.70Current price $27$27.00 - $137.70Current price $27 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Original price $23 - Original price $138Original price $23 - Original price $138Original price $69$69$23.00 - $117.30Save 67%$23.00 - $117.30Original price $23.00 - Original price $138.00Original price $23.00 - Original price $138.00Original price $69.00$23.00 - $117.30$23.00 - $117.30Current price $23$23.00 - $117.30Current price $23 -
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