Dirty Genes® - MTHFR Supplements
If you have an MTHFR gene SNP, you need supplementation that is bioavailable and doesn’t slow down your methylation processes. MTHFR (short for methylenetetrahydrofolate reductase) produces an enzyme that helps regulate how well your DNA methylation cycle works. Polymorphisms mean that MTHFR less efficiently converts folic acid (vitamin B9) and vitamin B12 to active forms.
If you have an MTHFR gene SNP, you need supplementation that is bioavailable and doesn’t slow down your methylation processes. MTHFR (short for methylenetetrahydrofolate reductase) produces an enzyme that helps regulate how well your DNA methylation cycle works. Polymorphisms mean that MTHFR less efficiently converts folic acid (vitamin B9) and vitamin B12 to active forms.
An impaired MTHFR gene can also lead to high homocysteine levels, detoxification challenges, and an increased risk for other problems.
For optimal health, you need bioavailable, methylated nutrients like methylcobalamin (methyl-B12), L-5-MTHF (methylfolate), SAMe, creatine, phosphatidylcholine, and more.
These work to support your body’s methylation processes by reducing the effort needed to activate them.
Your MTHFR gene mutation doesn’t have to confuse you. Get started with MTHFR supplements today. Try Seeking Health’s popular Optimal Multivitamin for comprehensive nutrient support. Or get HomocysteX Plus, which helps to support normal homocysteine conversion. B Complex Plus is a great way to support a healthy MTHFR enzyme.
Not sure where to start with a multivitamin? Use this chart to compare products.
All Products
Best Sellers
Featured Products
Shop by
All Products
Best Sellers
Featured Products
-
Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!†
Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).†
Optimal PC
SHOP NOW $454.9Rated 4.9 out of 5 stars170 ReviewsFrom $45Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...
View full detailsOriginal price $45 - Original price $270Original price $45 - Original price $270Original price $135$135$45.00 - $229.50(Save 67%)$45.00 - $229.50Original price $45.00 - Original price $270.00Original price $45.00 - Original price $270.00Original price $135.00$45.00 - $229.50$45.00 - $229.50Current price $45$45.00 - $229.50Current price $45 -
Promote the healthy development of your baby’s brain, spinal cord, and immune system while supporting your pregnancy health with Prenatal Essentials!†
Prenatal Essentials—Contains only the essential nutrients you need in superior and bioavailable forms, including folinic acid, bioactive B12, and chelated minerals for targeted pregnancy support.†
Best SellerImprovedPrenatal Essentials
SHOP NOW $354.8Rated 4.8 out of 5 stars484 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your prenatal vitamin essentials Bioavailable B12 and folate support healthy methylati...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Optimal Focus
SHOP NOW $504.6Rated 4.6 out of 5 stars134 ReviewsFrom $50Promotes a relaxed, focused state of mind to help you get things done with ease† Is this product right for me? Do you find yourself switching...
View full detailsOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00(Save 67%)$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!†
PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.†
Best SellerPQQ Lozenge
SHOP NOW $354.7Rated 4.7 out of 5 stars320 ReviewsFrom $35Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Get the high-strength, methyl-free prenatal you need to protect you and your baby’s health with Optimal Prenatal MF!†
Optimal Prenatal MF—The first non-methylated prenatal vitamin of its kind that includes bioavailable and well-tolerated sources of B12 and folate that are absolutely critical for prenatal health.†
ImprovedOptimal Prenatal MF
SHOP NOW $654.9Rated 4.9 out of 5 stars76 ReviewsFrom $65Provides comprehensive preconception, prenatal and postnatal nutrition with bioavailable, non-methylated forms of folate and B12 to support a heal...
View full detailsOriginal price $65 - Original price $390Original price $65 - Original price $390Original price $195$195$65.00 - $331.50(Save 67%)$65.00 - $331.50Original price $65.00 - Original price $390.00Original price $65.00 - Original price $390.00Original price $195.00$65.00 - $331.50$65.00 - $331.50Current price $65$65.00 - $331.50Current price $65 -
Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Bile Nutrients.†
Bile Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Bile Nutrients
SHOP NOW $404.7Rated 4.7 out of 5 stars150 ReviewsFrom $40Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with or without a gal...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00(Save 67%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
ImprovedPrenatal Essentials MF
SHOP NOW $355.0Rated 5.0 out of 5 stars112 ReviewsFrom $35Key Benefits and Actions† 2 capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Give your baby the best start by supporting healthy spine and brain development with Prenatal Essential Chewable!†
Prenatal Essential Chewable—A targeted prenatal vitamin formulated by epigenetics expert Dr. Ben Lynch ND that provides the foundational basics needed for a healthy pregnancy in an easy-to-take chewable.†
Out of Stock
Prenatal Essentials Chewable
4.3Rated 4.3 out of 5 stars45 ReviewsFrom $46Provides the foundational nutrients you need to support healthy fertility, pregnancy, and breastfeeding in a delicious, easy-to-chew tablet with b...
View full detailsOriginal price $46 - Original price $276Original price $46 - Original price $276Original price $138$138$46.00 - $234.60(Save 67%)$46.00 - $234.60Original price $46.00 - Original price $276.00Original price $46.00 - Original price $276.00Original price $138.00$46.00 - $234.60$46.00 - $234.60Current price $46$46.00 - $234.60Current price $46Out of Stock
-
Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!†
Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).†
Optimal PC
SHOP NOW $454.9Rated 4.9 out of 5 stars170 ReviewsFrom $45Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...
View full detailsOriginal price $45 - Original price $270Original price $45 - Original price $270Original price $135$135$45.00 - $229.50(Save 67%)$45.00 - $229.50Original price $45.00 - Original price $270.00Original price $45.00 - Original price $270.00Original price $135.00$45.00 - $229.50$45.00 - $229.50Current price $45$45.00 - $229.50Current price $45 -
Promote the healthy development of your baby’s brain, spinal cord, and immune system while supporting your pregnancy health with Prenatal Essentials!†
Prenatal Essentials—Contains only the essential nutrients you need in superior and bioavailable forms, including folinic acid, bioactive B12, and chelated minerals for targeted pregnancy support.†
Best SellerImprovedPrenatal Essentials
SHOP NOW $354.8Rated 4.8 out of 5 stars484 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your prenatal vitamin essentials Bioavailable B12 and folate support healthy methylati...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Optimal Focus
SHOP NOW $504.6Rated 4.6 out of 5 stars134 ReviewsFrom $50Promotes a relaxed, focused state of mind to help you get things done with ease† Is this product right for me? Do you find yourself switching...
View full detailsOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00(Save 67%)$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!†
PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.†
Best SellerPQQ Lozenge
SHOP NOW $354.7Rated 4.7 out of 5 stars320 ReviewsFrom $35Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Get the high-strength, methyl-free prenatal you need to protect you and your baby’s health with Optimal Prenatal MF!†
Optimal Prenatal MF—The first non-methylated prenatal vitamin of its kind that includes bioavailable and well-tolerated sources of B12 and folate that are absolutely critical for prenatal health.†
ImprovedOptimal Prenatal MF
SHOP NOW $654.9Rated 4.9 out of 5 stars76 ReviewsFrom $65Provides comprehensive preconception, prenatal and postnatal nutrition with bioavailable, non-methylated forms of folate and B12 to support a heal...
View full detailsOriginal price $65 - Original price $390Original price $65 - Original price $390Original price $195$195$65.00 - $331.50(Save 67%)$65.00 - $331.50Original price $65.00 - Original price $390.00Original price $65.00 - Original price $390.00Original price $195.00$65.00 - $331.50$65.00 - $331.50Current price $65$65.00 - $331.50Current price $65 -
Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Bile Nutrients.†
Bile Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Bile Nutrients
SHOP NOW $404.7Rated 4.7 out of 5 stars150 ReviewsFrom $40Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with or without a gal...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00(Save 67%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
ImprovedPrenatal Essentials MF
SHOP NOW $355.0Rated 5.0 out of 5 stars112 ReviewsFrom $35Key Benefits and Actions† 2 capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Give your baby the best start by supporting healthy spine and brain development with Prenatal Essential Chewable!†
Prenatal Essential Chewable—A targeted prenatal vitamin formulated by epigenetics expert Dr. Ben Lynch ND that provides the foundational basics needed for a healthy pregnancy in an easy-to-take chewable.†
Out of Stock
Prenatal Essentials Chewable
4.3Rated 4.3 out of 5 stars45 ReviewsFrom $46Provides the foundational nutrients you need to support healthy fertility, pregnancy, and breastfeeding in a delicious, easy-to-chew tablet with b...
View full detailsOriginal price $46 - Original price $276Original price $46 - Original price $276Original price $138$138$46.00 - $234.60(Save 67%)$46.00 - $234.60Original price $46.00 - Original price $276.00Original price $46.00 - Original price $276.00Original price $138.00$46.00 - $234.60$46.00 - $234.60Current price $46$46.00 - $234.60Current price $46Out of Stock
-
Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!†
Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).†
Optimal PC
SHOP NOW $454.9Rated 4.9 out of 5 stars170 ReviewsFrom $45Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...
View full detailsOriginal price $45 - Original price $270Original price $45 - Original price $270Original price $135$135$45.00 - $229.50(Save 67%)$45.00 - $229.50Original price $45.00 - Original price $270.00Original price $45.00 - Original price $270.00Original price $135.00$45.00 - $229.50$45.00 - $229.50Current price $45$45.00 - $229.50Current price $45 -
Promote the healthy development of your baby’s brain, spinal cord, and immune system while supporting your pregnancy health with Prenatal Essentials!†
Prenatal Essentials—Contains only the essential nutrients you need in superior and bioavailable forms, including folinic acid, bioactive B12, and chelated minerals for targeted pregnancy support.†
Best SellerImprovedPrenatal Essentials
SHOP NOW $354.8Rated 4.8 out of 5 stars484 ReviewsFrom $35Key Benefits and Actions† 2-capsule serving size provides your prenatal vitamin essentials Bioavailable B12 and folate support healthy methylati...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Start the day off right and support healthy cognition, focus, clarity, and learning on the job or in school with Optimal Focus!†
Optimal Focus—A stimulant-free supplement that supports healthy learning, memory, attention, and concentration no matter what stage of life.†
Optimal Focus
SHOP NOW $504.6Rated 4.6 out of 5 stars134 ReviewsFrom $50Promotes a relaxed, focused state of mind to help you get things done with ease† Is this product right for me? Do you find yourself switching...
View full detailsOriginal price $50 - Original price $300Original price $50 - Original price $300Original price $150$150$50.00 - $255.00(Save 67%)$50.00 - $255.00Original price $50.00 - Original price $300.00Original price $50.00 - Original price $300.00Original price $150.00$50.00 - $255.00$50.00 - $255.00Current price $50$50.00 - $255.00Current price $50 -
Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!†
PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.†
Best SellerPQQ Lozenge
SHOP NOW $354.7Rated 4.7 out of 5 stars320 ReviewsFrom $35Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Get the high-strength, methyl-free prenatal you need to protect you and your baby’s health with Optimal Prenatal MF!†
Optimal Prenatal MF—The first non-methylated prenatal vitamin of its kind that includes bioavailable and well-tolerated sources of B12 and folate that are absolutely critical for prenatal health.†
ImprovedOptimal Prenatal MF
SHOP NOW $654.9Rated 4.9 out of 5 stars76 ReviewsFrom $65Provides comprehensive preconception, prenatal and postnatal nutrition with bioavailable, non-methylated forms of folate and B12 to support a heal...
View full detailsOriginal price $65 - Original price $390Original price $65 - Original price $390Original price $195$195$65.00 - $331.50(Save 67%)$65.00 - $331.50Original price $65.00 - Original price $390.00Original price $65.00 - Original price $390.00Original price $195.00$65.00 - $331.50$65.00 - $331.50Current price $65$65.00 - $331.50Current price $65 -
Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Bile Nutrients.†
Bile Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Bile Nutrients
SHOP NOW $404.7Rated 4.7 out of 5 stars150 ReviewsFrom $40Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with or without a gal...
View full detailsOriginal price $40 - Original price $240Original price $40 - Original price $240Original price $120$120$40.00 - $204.00(Save 67%)$40.00 - $204.00Original price $40.00 - Original price $240.00Original price $40.00 - Original price $240.00Original price $120.00$40.00 - $204.00$40.00 - $204.00Current price $40$40.00 - $204.00Current price $40 -
Support a healthy lifestyle and balanced diet during pregnancy, especially if you’re methyl-sensitive with Prenatal Essentials MF.†
Prenatal Essentials MF—A concise yet powerful prenatal multivitamin. It supports methylation with bioavailable, methyl-free forms of key pregnancy nutrients.†
ImprovedPrenatal Essentials MF
SHOP NOW $355.0Rated 5.0 out of 5 stars112 ReviewsFrom $35Key Benefits and Actions† 2 capsule serving size provides your essential daily prenatal nutrients in methyl-free forms Supports healthy immune, ...
View full detailsOriginal price $35 - Original price $210Original price $35 - Original price $210Original price $105$105$35.00 - $178.50(Save 67%)$35.00 - $178.50Original price $35.00 - Original price $210.00Original price $35.00 - Original price $210.00Original price $105.00$35.00 - $178.50$35.00 - $178.50Current price $35$35.00 - $178.50Current price $35 -
Give your baby the best start by supporting healthy spine and brain development with Prenatal Essential Chewable!†
Prenatal Essential Chewable—A targeted prenatal vitamin formulated by epigenetics expert Dr. Ben Lynch ND that provides the foundational basics needed for a healthy pregnancy in an easy-to-take chewable.†
Out of Stock
Prenatal Essentials Chewable
4.3Rated 4.3 out of 5 stars45 ReviewsFrom $46Provides the foundational nutrients you need to support healthy fertility, pregnancy, and breastfeeding in a delicious, easy-to-chew tablet with b...
View full detailsOriginal price $46 - Original price $276Original price $46 - Original price $276Original price $138$138$46.00 - $234.60(Save 67%)$46.00 - $234.60Original price $46.00 - Original price $276.00Original price $46.00 - Original price $276.00Original price $138.00$46.00 - $234.60$46.00 - $234.60Current price $46$46.00 - $234.60Current price $46Out of Stock
Recently Viewed
Support the healthy conversion of fat into energy with Acetyl-L-Carnitine.†
Acetyl-L-carnitine—A unique, bioavailable amino acid that supports healthy energy production, brain and nervous system function, and fat metabolism.†
Acetyl-L-Carnitine
Key Benefits and Actions† Supports conversion of fat into energy Supports healthy heart, brain, muscle, and sperm function Supports athletic per...
View full details