- Use HEPA air purifiers in home and office
- Avoid driving with windows down in traffic
- Keep car air circulation internal, not pulling in outside air
- Avoid heavily scented public spaces during rebuilding phase
The Essential Three: Your
Core GST/GPX Support Stack†
1. Glutathione Plus Lozenges –
The master antioxidant in an easy-to-absorb lozenge form. This is the actual compound that both GST and GPX use to neutralize toxins and hydrogen peroxide. Lozenges allow for gentle, controlled dosing and superior absorption.†
Alternative: If you prefer capsules, Glutathione Plus Capsules provide the same support in capsule form.
2. Liposomal Vitamin C Plus –
Works synergistically with glutathione to enhance antioxidant defense, helps recycle oxidized glutathione back to active form, and provides necessary antioxidant protection while you support your system.†
3. Optimal Electrolyte –
Essential for supporting healthy detox pathways, helping maintain normal "detox responses", and hydration during the clearance process. Many people with dirty GST/GPX can be dehydrated at the cellular level.†
Additional Support (If Needed)
Once you're tolerating the core three products, you may benefit from:
N-Acetyl Cysteine (NAC)
provides the building blocks for your body to make its own glutathione†
Riboflavin (Vitamin B2)
essential for glutathione recycling and GPX function†
Selenium
required cofactor for GPX enzyme (or eat 1-2 Brazil nuts daily)
Methylation Support (L-Methylfolate, Methyl-B12)
upstream support for glutathione production†
Liver Nutrients
comprehensive liver detox support†
PQQ, Molybdenum, Calcium D-Glucarate, Curcumin
targeted additional support†
Plus Lifestyle Foundations
Stress management practices
meditation, breathwork, boundaries, nature time to reduce hydrogen peroxide production
Prioritized sleep
7-9 hours in dark, cool, quiet room to support glutathione recycling†
Movement without overexertion –
moderate exercise that doesn't overwhelm GPX capacity
Reduce chemical exposures
remove air fresheners, switch to fragrance-free products, filter air and water
Best for you if:
-
You have chemical sensitivities that limit where you can go and what you can use
-
You react to medications, supplements, or foods that others tolerate fine
-
You have premature graying, chronic fatigue, or exercise intolerance
-
You've been diagnosed with autoimmune conditions or chronic inflammation
-
You feel worse in environments with fragrances, new materials, or cleaning products
Individual Product Guide: The Essential Three
Glutathione with Cofactors Lozenges ( formerly Glutathione Plus Lozenge )
Ammunition for Everyday Antioxidant Support†
$50.00
What it does
Provides reduced glutathione in an easy-to-absorb lozenge form. This is the actual compound that GST and GPX use to neutralize toxins and hydrogen peroxide. The lozenge format allows for gentle, controlled dosing and superior absorption.†
Best if:
- You experience chemical sensitivities and want direct glutathione support.†
- You want precise dose control (can break lozenges into quarters or halves)
- You prefer lozenges over capsules
How to take
START LOW – ¼ to ½ lozenge for first 1-2 weeks, let dissolve slowly under tongue and swallow. Increase very gradually as tolerated. Take with vitamin C to enhance stability and function.†
Alternative: Glutathione Plus Capsules provide the same support in capsule form if you prefer swallowing capsules over lozenges.
Signs you may be taking too little
Less noticeable support for antioxidant balance, healthy healing, and normal glutathione activity.
Signs you may be taking too much
Loose stools or diarrhea (reduce dose to bowel tolerance). Rarely: oxalate kidney stone risk in susceptible individuals with history.
Liposomal Vitamin C
Normal Antioxidant Function and Recycling†
$38.00
What it does
Provides high-dose vitamin C in liposomal form for superior absorption. Works synergistically with glutathione to enhance antioxidant defense and helps recycle oxidized glutathione back to active form. Essential foundation for GST/GPX support.†
Best if:
- You need foundational antioxidant support before introducing glutathione
- You want to enhance glutathione function and stability
- You experience frequent inflammation or infections
How to take
Start with 1 serving daily, increase to 2-3 servings daily as tolerated. Take with or between meals.
Signs you may be taking too little
No changes in energy, chemical tolerance, or responses after consistent use at adequate doses.
Signs you may be taking too much
Loose stools or diarrhea (reduce dose to bowel tolerance). Rarely: oxalate kidney stone risk in susceptible individuals with history.
Optimal Electrolyte
Support my detox pathways†
$40.00
What it does
Provides essential electrolytes (sodium, potassium, magnesium) to support cellular hydration, healthy pathways, and "detox response" symptoms. Many people with dirty GST/GPX can be dehydrated at the cellular level, which impacts toxin elimination.†
Best if:
- You're starting GST/GPX support and want healthy detox responses.
- You experience frequent fatigue or feel worse when detoxing
- You experience headaches, dizziness, or brain fog during detox
How to take
1 serving daily in water, increase to 2-3 servings if engaging in sauna therapy or experiencing detox symptoms. Best taken throughout the day, not all at once.
Signs you may be taking too little
No changes in hydration, detox responses or toxin elimination, headaches and fatigue during use.
Signs you may be taking too much
Rare with proper hydration; may cause loose stools if magnesium content is too high for individual tolerance.
How to Start Supporting GST/GPX (Without Overwhelming Your System)†
People with dirty GST/GPX often have severe "detox responses" when starting support. This happens when you mobilize stored toxins faster than your impaired system can clear them. The key is to start gently and build gradually.
Phase 1: Preparation (First 1-2 Weeks)
Remove Synthetic Folic Acid
- Check labels on cereals, breads, bars, shakes for folic acid
- Swap to non-fortified options
- Replace multivitamins with folate or L-methylfolate versions
Start Optimal Electrolyte daily to support hydration and detox pathways.†
Phase 2: Gentle Support (Weeks 2-4)
Focus: Begin antioxidant and cofactor support.†
- Add Liposomal Vitamin C Plus – start with 1 serving daily, increase to 2-3 servings as tolerated
- Add Riboflavin (B2) if using additional support – essential for glutathione recycling
- Continue environmental cleanup and foundational practices
Phase 3: Glutathione Introduction (Weeks 4-6)
Focus: Carefully introduce glutathione (START LOW)
- Add Glutathione Plus Lozenges – START WITH ¼ TO ½ LOZENGE for first 1-2 weeks
- Let it dissolve slowly under your tongue for best absorption.†
- Take with vitamin C to enhance stability and function
- Increase dose ONLY if tolerated; some people need to stay at ¼ dose for weeks
- If you feel worse: Reduce dose by half or pause, focus on vitamin C and electrolytes
Phase 4: Additional Support (Week 6+)
Focus: Layer in targeted support as tolerated
- Consider adding NAC for glutathione building blocks†
- Add Selenium (supplement or Brazil nuts) for GPX enzyme support.†
- Add Methylation Support (L-Methylfolate, Methyl-B12) if you have MTHFR patterns.†
- Add Liver Nutrients or other targeted support based on your specific needs
Key principle: Add one new product at a time, wait 3-5 days to assess tolerance, then add the next. If you react to something, remove it and stabilize before proceeding.
Signs You May Have Started Too Aggressively
-
Increased brain fog, headaches, or cognitive symptoms
-
Worsening fatigue or "hitting a wall" – feeling more exhausted than before
-
Flu-like symptoms – body aches, malaise, feeling "toxic"
-
Mood swings, irritability, or restlessness – from mobilized toxins affecting neurotransmitters
-
Skin breakouts, rashes, or worsening skin issues
-
Digestive upset – nausea, diarrhea, cramping
-
Sleep disruption – poor or restless sleep
If this happens: Step back, reduce doses by 50-75%, let things settle for a week or two, then resume more slowly.
Potential Signs GST/GPX Support Is Working†
-
Enhanced mental clarity – clear thinking and healthy recall.
-
Greater comfort in everyday environments– can go to stores, use elevators, be around people without feeling overwhelmed
-
Increased tolerance for a variety of foods and products - without frequent discomfort.
-
Healthy energy and stamina – exercise feels energizing instead of depleting
-
Better stress resilience – during day-to-day demands.
-
Perceived stability – healthy fluctuations in emotional responses.
-
Healthy sleep quality – falling asleep with ease and can maintain rest.
-
Changes in hair color – if graying, some individuals may notice slower progression.
-
Changes in inflammation markers – if tracking labs
Foundations: Making Life Easier
For GST/GPX (Before Supplements)
Before stacking pills, you want to stop pouring gasoline on the detox fire.
1. Reduce Incoming Chemical Burden (Turn Down The Faucet)
Air Quality:
Water Quality:
- Install whole-house water filter (chlorine, chloramines, heavy metals)
- Use quality drinking water filter (reverse osmosis or carbon-based)
- Filter shower water (skin is highly absorptive)
Personal Care and Household Products:
- Switch to fragrance-free, unscented products (laundry, cleaning, body care)
- Avoid synthetic fragrances, air fresheners, scented candles
- Use natural, plant-based cleaning products
- Choose cosmetics and personal care products carefully (EWG Skin Deep database)
Food and Diet:
- Prioritize organic produce, especially "Dirty Dozen"
- Choose wild-caught fish over farmed (lower toxin load)
- Avoid processed and packaged foods with preservatives and additives
- Reduce or eliminate alcohol (especially wine with sulfites if sensitive)
- Filter drinking water and cooking water
Environmental Exposures:
- Avoid secondhand smoke and smoking environments
- Minimize plastic use (especially for food storage and hot beverages)
- Avoid non-stick cookware (use stainless steel, cast iron, ceramic)
- Be cautious with new cars, new furniture, new buildings (off-gassing VOCs)
- Avoid lawn chemicals, pesticides, herbicides around home
1. Reduce Incoming Chemical Burden (Turn Down The Faucet)
GST/GPX-supportive foods:
For cysteine (rate-limiting for glutathione)
- Red meat (grass-fed beef, lamb)
- Poultry (chicken, turkey, especially dark meat)
- Eggs (particularly yolks)
- Sunflower seeds
- Cruciferous vegetables (broccoli, cabbage, cauliflower, Brussels sprouts)
- Allium vegetables (garlic, onions)
- Asparagus
For selenium (GPX cofactor):
- Brazil nuts (1-2 daily, most concentrated source)
- Wild-caught seafood (salmon, halibut, sardines, tuna)
- Grass-fed beef and organ meats (liver, kidney)
- Pasture-raised eggs
- Brown rice
- Sunflower seeds
For riboflavin/B2 (glutathione recycling):
- Chicken liver and other organ meats
- Lamb
- Mushrooms (especially portobello, cremini)
- Spinach and dark leafy greens
- Almonds
- Wild-caught salmon and mackerel
- Pasture-raised eggs
For fiber (detox elimination):
- Artichokes, asparagus
- Leafy greens (kale, chard, collards)
- Cruciferous vegetables (broccoli, Brussels sprouts, cabbage, cauliflower)
- Berries (raspberries, blackberries, blueberries)
- Avocado
- Chia seeds, flax meal
- Beans and lentils (if tolerated)
- Pears, apples with skin
- Target: 30-40g fiber daily
Sulfur-rich foods (support GST pathways):
- Cruciferous vegetables
- Allium vegetables (garlic, onions, leeks, shallots)
- Eggs
- Quality meats and fish
- Asparagus
How GST/GPX Connect To The Rest Of Your Super Seven
GST/GPX sit at a critical intersection in your gene network:
MTHFR and methylation
- methylation produces glutathione;
- dirty MTHFR = low glutathione = disabled GST/GPX[cite:6]
COMT
- requires methylation and handles catechol detox;
- when GST/GPX are dirty, overall toxic burden increases and COMT gets overwhelmed
MAOA –
- stress and mood genes;
- chronic stress produces hydrogen peroxide that dirty GPX can't clear, worsening mood and energy
DAO
- histamine clearance;
- oxidative stress and inflammation increase histamine;
- dirty GST/GPX worsen DAO patterns
NOS3
- cardiovascular and circulation;
- oxidative stress damages blood vessels and impairs nitric oxide;
- GPX protects against this
PEMT
- liver and cell membrane health;
- toxic burden stresses liver, whereas GST works by supporting GST/GPX and reduces the burden on PEMT
Your "I can't handle anything" story is a common experience, and it’s not a weakness and not "all in your head." It's what life looks like when detoxification and antioxidant defense are overwhelmed, and GST/GPX have been working under increased demand for too long. When you change the incoming chemical burden, support glutathione production and function, provide essential cofactors, prioritize sleep and stress management, and—when appropriate—use focused GST/GPX-supportive products, you stop fighting a losing battle and give your body the protection and resilience it needs.†
†These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.