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Active B12 5000

  • Potent dose of bioavailable B12 in a delicious lozenge
  • Healthy methylation and MTHFR support
  • Supports healthy homocysteine levels

Who Needs Active B12 5000

Your body prefers bioavailable nutrients. This means few (or no) enzymatic steps are required to transform it into a usable form. The two most bioactive forms of B12 are methylcobalamin and adenosylcobalamin.

Bioavailability is particularly crucial when working to replenish vitamin B12 levels. Ideally, B12 is also in a format that supports optimal digestion and absorption, such as a lozenge.

Active B12 5000 provides a potent dose of bioavailable vitamin B12 in a delicious, well-absorbed lozenge. Each serving contains a 5,000 mcg mixture of methylcobalamin and adenosylcobalamin.

You need steady energy to feel your best. Vitamin B12 plays important roles in energy production and much more.

Vitamin B12 is essential for:

  • Cognitive function
  • Red blood cell formation
  • Methylation
  • Homocysteine recycling
  • Cardiovascular health
  • DNA production and expression
  • Nervous system health and development

Vitamin B12 deficiency is common. It is one of the most difficult nutrients for your body to absorb and utilize. Symptoms of vitamin B12 deficiency can include fatigue, memory issues, and tingling in your toes or fingers.

Factors such as genetic mutations, low stomach acid, a vegetarian or vegan diet, and insufficient intrinsic factor (pernicious anemia) can all contribute to low B12 levels. For these reasons, it’s critical to consume B12 in bioavailable, optimally-absorbed forms.

Active B12 5000 provides bioactive forms of vitamin B12 that your body can readily recognize and utilize. These delicious lozenges are designed to be rapidly digested and absorbed through your intestines and cell walls.

Most B12 dietary supplements contain the active ingredient cyanocobalamin. Before it can be used, your liver must first convert cyanocobalamin into an active form and discard the cyanide. In addition, it appears that the body uses methylcobalamin more efficiently than cyanocobalamin.

Here at Seeking Health, you’ll never find the cyanide-containing form, cyanocobalamin. Instead, you’ll only find bioavailable forms of vitamin B12 that your body can quickly recognize and utilize.

Active B12 5000 provides a potent dose of vitamin B12 in the bioactive forms of methylcobalamin and adenosylcobalamin. These delicious, well-absorbed lozenges support healthy methylation, MTHFR, and homocysteine levels.

How much vitamin B12 do you need?

Everyone has different needs for vitamin B12. Work with a qualified healthcare professional to determine the best dose for your individual needs.

Active B12 5000 provides a potent dose of 5,000 mcg (5 mg) per serving. The lozenges can be broken down into halves or quarters if a smaller dose is desired.

  • For a lower dose of vitamin B12 per lozenge (1,000 mcg), consider Active B12 1000.
  • For a similar product without the methyl B12, consider Hydro-Adeno B12.
  • For vitamin B12 in the form of hydroxocobalamin, consider Hydroxo B12.

It’s never been easier (or tastier!) to support optimal B12 levels in your body. Add Active B12 5000 to your methylation support protocol for optimal wellness.

Customer Review

Trusted Product

My body energy improves with daily B12 and at 67 years old, I really appreciate that. I trust the science and integrity behind Seeking Health products, so this has been my go to for years.

Key Ingredients In Active B12 5000

  • Vitamin B12: Included in two active coenzyme forms, methylcobalamin and adenosylcobalamin. These bioavailable forms help methylfolate donate methyl groups for optimal DNA expression. They also support the transformation of food energy into cellular energy.

Why Active B12 5000 Works

Folate needs the help of vitamin B12 for proper methylation.

Do you take methylfolate to support methylation and homocysteine metabolism? These processes cannot happen with methylfolate alone. They also require adequate B12.

With the help of B12, supplemental methylfolate bypasses the MTHFR enzyme and is brought into the methylation pathway via the MTR enzyme. Ultimately, methylfolate donates its methyl groups to regulate DNA expression, healthy homocysteine levels, and much more.

Without sufficient bioavailable B12, you cannot effectively break down the amino acid homocysteine to methionine. Your body needs methyl B12 and methylfolate for this to happen. Elevated homocysteine levels have been correlated with cardiovascular concerns.

If you have an MTHFR genetic mutation, you may need additional support for methylation and recycling homocysteine to methionine. The human body uses methylcobalamin to carry out these functions.

Adenosylcobalamin is a methyl-free, bioavailable form of B12. Also known as Adeno B12, it is found in your cells’ mitochondria to support energy production. Here, it acts as a coenzyme to create energy (ATP) from cholesterol, branched-chain amino acids, odd chain fatty acids, and propionate. It does this by converting a derivative of these compounds into succinyl-CoA. This compound can then enter the Krebs cycle to generate cellular energy (ATP).

Methylcobalamin and adenosylcobalamin can both enter the cell’s cobalamin pool. When needed, your body pulls cobalamin from this pool to use in various processes, including methylation and homocysteine breakdown.

Active B12 5000 provides a potent dose of methylcobalamin and adenosylcobalamin in a delicious, optimally-absorbed lozenge. For a lower dose, consider Active B12 1000.

It’s never been tastier (or easier) to support healthy methylation, homocysteine levels, and energy!

Active B12 5000
Supplement Facts

Serving Size: 1 Lozenge
Servings Per Container: 60

Vitamin B12 (as MECOBALACTIVE® methylcobalamin and adenosylcobalamin) 5000 mcg 208,333%
DV = Daily Value

Other Ingredients: Xylitol, ascorbyl palmitate, silica, and natural flavors.

MECOBALACTIVE® is a registered trademark of HealthTech BioActives SLU d.b.a. Ferrer HealthTech.

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Lozenges
  • How To Store: Keep closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, and Artificial Preservatives

How to Use Active B12 5000

Suggested Use

Initial use for the first week, take ½ lozenge by mouth, let dissolve slowly, then swallow. If needing more support, increase to 1 full lozenge. Take as needed. . Do not take within 5 hours of bedtime as it may interfere with sleep. Use as directed by your healthcare professional.


Consult with your healthcare professional prior to use. Do not use if tamper seal is damaged.

FAQs for Active B12 5000

What is the purpose of each ingredient in Active B12 5000?

Ingredients Purpose
Vitamin B12 (Methylcobalamin and adenosylcobalamin) Supports the normal conversion of homocysteine to methionine, healthy methylation and metabolism, cognitive health, and healthy energy levels

Who is Active B12 5000 intended for?

Active B12 5000 is intended for those seeking a potent, optimally-absorbed, vitamin B12 lozenge containing a methylated form to support healthy methylation processes and energy production.

Which Vitamin B12 is right for me?

Click here to view our Vitamin B12 Supplement Comparison Chart.

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What our customers say

Real reviews from real customers.

Rated 4.9 out of 5 stars
Based on 115 reviews
Total 5 star reviews: 109 Total 4 star reviews: 5 Total 3 star reviews: 0 Total 2 star reviews: 1 Total 1 star reviews: 0
97%would recommend these products
115 reviews
  • SH
    Sarah H.
    Verified Buyer
    Active B12 5000
    Active B12 5000
    I recommend this product
    Rated 5 out of 5 stars
    excellent product

    I take 2-3 tablets daily to keep my b12 levels where they need to be to feel my best. I have been using Seeking Health products for years and trust the quality of their products. Super fast shipping as well.

  • CS
    Christina S.
    Verified Buyer
    Active B12 5000
    Active B12 5000
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago

    I like this chewable version which is less messy than liquid B12 I’ve used. It delivers 5,000 units which is what I’m recommended to take.

  • RT
    Renee T.
    Verified Buyer
    Active B12 5000
    Active B12 5000
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago


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