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Adeno B12

  • Powerful energy production support
  • Supports healthy methylation
  • Delicious lozenge for optimal absorption

Who Needs Adeno B12

Do you want to support healthy energy levels all day long?

Are you sensitive to methylated nutrients, but want to support healthy methylation in your body?

You may need a methyl-free form of vitamin B12.

Vitamin B12 deficiency is common. It is one of the most difficult nutrients for your body to absorb and utilize.

When working to replenish B12 levels, you need a bioavailable form that is readily utilized by your body. Ideally, B12 is in a format that supports optimal digestion and absorption, such as a lozenge.

If you’re sensitive to methylated nutrients, you also want a form free of methyl groups.

Adeno B12 contains 3,000 mcg of bioavailable vitamin B12 per delicious, optimally-absorbing lozenge. The methyl-free form of adenosylcobalamin supports optimal vitamin B12 levels in your body.

Adeno B12 provides a powerful dose of methyl-free vitamin B12. One tasty lozenge supports healthy energy and optimal methylation all day long.

Our Adeno B12 lozenges are naturally sweetened with xylitol. These tasty lozenges deliver B12 in a form that is designed to be rapidly digested and absorbed through your intestines and cell walls.

Some people experience side effects from methylated nutrients. These can include nervousness, headaches, or rapid heartbeat after taking methylcobalamin or methylfolate.

Adeno B12 provides vitamin B12 in the non-methyl form of adenosylcobalamin. This methyl-free form takes a few additional enzyme steps before the methyl groups are liberated for your body to use. This slower delivery can provide relief and comfort in those sensitive to methylated nutrients.

Adenosylcobalamin is particularly unique. It is the form of B12 present in mitochondria, the energy powerhouse of cells. It acts as a coenzyme that assists in keeping healthy ATP (energy) levels in each and every cell.

You shouldn’t be struggling with side effects related to your supplements. Now, you can provide your body with potent, bioavailable B12...without the headache of methyl donors!

Customer Review

Seems to work well!

I consistently have a tendency to run low on B12. The Adeno B12 definitely gives me a little boost in energy and I feel good taking it. It tastes very good as well. It is a nice mild pleasant taste, which I appreciate. ~Anna

Key Ingredients In Adeno B12

  • Adenosylcobalamin: A methyl-free form of vitamin B12. Large concentrations are found naturally in the cell’s mitochondria, where it plays roles in energy production. This form of B12 also supports healthy methylation processes by indirectly providing cobalamin for the MTR enzyme.

Why Adeno B12 Works

Adenosylcobalamin is a non-methylated, active form of vitamin B12. It is present in the mitochondria of cells in large quantities. Here, it supports cellular energy production (ATP).

Adenosylcobalamin is used as a coenzyme for the Methylmalonyl CoA Mutase (MCM) enzyme. This important enzyme facilitates the creation of energy from cholesterol, branched-chain amino acids, odd chain fatty acids, and propionate (from gut bacteria). It converts these substances into succinyl CoA, which can enter the Krebs cycle to create ATP (energy). By supplementing with adenosylcobalamin, you provide your body with the compounds necessary to support healthy energy production.

This methyl-free B12 is readily converted into cobalamin that enters the cell’s cobalamin pool. When needed, cobalamin is pulled from this pool for your body to use in various processes, including methylation. Cobalamin plays essential roles in the methylation cycle to support homocysteine breakdown to methionine.

Homocysteine levels may increase with poor homocysteine metabolism. Cardiovascular and general wellness are dependent upon maintaining healthy homocysteine levels.

Your body needs vitamin B12 and methylfolate (L-5-MTHF) to metabolize homocysteine into methionine via the MTR enzyme. From methionine, SAMe is created, your body’s main methyl donor. SAMe donates methyl groups to support your body’s methylation processes, including DNA expression.

Without adequate B12, your body cannot effectively utilize methylfolate through the MTR enzyme. By consuming Adeno B12, you are giving your body indirect methylation support without the side effects some people experience from methyl groups.

Most B12 dietary supplements contain the active ingredient cyanocobalamin. Before it can be used, your liver must first convert cyanocobalamin into an active form and discard the cyanide. If a person already has exposure to cyanide from cigarette smoke, fire smoke, or other sources, an alternative form of B12 such as adenosylcobalamin may be a healthier option.

Here at Seeking Health, you’ll never find the cyanide-containing form, cyanocobalamin. Instead, you’ll only find bioavailable forms of vitamin B12 that your body can quickly recognize and utilize.

Because B12 needs folate to support proper methylation, be sure to pair Adeno B12 with a bioactive form of folate, such as methyl-free Folinic Acid.

It has never been easier (or more delicious!) to get your daily B12. If you’re looking to support healthy energy and methylation (without the side effects of methyl groups), Adeno B12 is the perfect formula for you!

Adeno B12
Supplement Facts

Serving Size: 1 Lozenge
Servings Per Container: 60

Vitamin B12 (as adenosylcobalamin) 3000 mcg 125,000%
DV = Daily Value

Other Ingredients: Xylitol, ascorbyl palmitate, silica, natural cherry flavor.

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Lozenges
  • How To Store: Keep closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, and Wheat

How to Use Adeno B12

Suggested Use

Initial use for the first week, take ½ a lozenge by mouth, let dissolve slowly, then swallow. If needing more support, increase to 1 full lozenge. Take as needed. Do not take within 5 hours of bedtime as it may interfere with sleep. Use as directed by your healthcare professional.


Consult with your healthcare practitioner prior to use. Do not use if tamper seal is damaged.

Suitable for


Delivery Method


How to Store

Keep closed in a cool, dry place out of reach by children.

FAQs for Adeno B12

What is the purpose of each ingredient in Adeno B12?

Ingredients Purpose
Vitamin B12 (as adenosylcobalamin) Supports energy production in the mitochondria as well as indirectly supports the normal conversion of homocysteine to methionine, healthy metabolism, methylation, and cognitive health

Who is Adeno B12 intended for?

Adeno B12 is intended for those seeking the mitochondrial form of vitamin B12 in an easy-to-deliver lozenge. Adenosylcobalamin is considered an active “coenzyme” form of B12, meaning it is used directly in B12-dependent enzyme reactions in the body. This form provides an alternative to methylcobalamin for individuals sensitive to methyl donors or methylated B vitamins.

Which vitamin B12 supplement is right for me?

Click here to view our Vitamin B12 Supplement Comparison Chart.

This article will help you determine if you need a methyl-free supplement..

If you have a question that's not addressed
here, see all frequently asked questions.


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What our customers say

Real reviews from real customers.

Rated 4.9 out of 5 stars
Based on 106 reviews
Total 5 star reviews: 94 Total 4 star reviews: 11 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 1
99%would recommend these products
106 reviews
  • JE
    Jana E.
    Verified Buyer
    Adeno B12
    Adeno B12
    I recommend this product
    Rated 5 out of 5 stars
    6 days ago
    Great product!

    This helps with energy slumps.

  • MM
    Monica M.
    Verified Buyer
    Adeno B12
    Adeno B12
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago

    At the suggestion of my doctor I started taking Adeno B to replace the vitamin B shots I had been taking for several years. I couldn’t believe how much more energy I had after only a few days.

  • KK
    Kamlesh Kumar A.
    Verified Buyer
    Adeno B12
    Adeno B12
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago

    I really like this product and it's available at a great price.

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