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Seeking Health we will be closed on May 27th in observance of the holiday. We will resume normal business hours on May 28th.
Seeking Health we will be closed on May 27th in observance of the holiday. We will resume normal business hours on May 28th.

Histamine Nutrients - Formerly Histamine Block Plus

  • Supports a healthy seasonal histamine response, outdoors and indoors
  • Provides nutrients needed to support healthy histamine breakdown
  • You will notice it works quite quickly

Who Needs Histamine Nutrients

Everyday you’re exposed to compounds which may trigger histamine release.

How is it that you’re struggling with histamine intolerance while others, who are exposed to the same things, are not?

The answer is you cannot break histamine down very well and they can.

Histamine intolerance is primarily caused by your reduced ability to break histamine down and eliminate it from your body.

In other words, your histamine genes are dirty.

Clean your histamine genes.

Experience what it’s like to breathe through your nose again and be free from giant red, itchy mosquito bites.

Histamine Nutrients cleans your histamine genes. It contains a synergistic collection of nutrients which support total body histamine breakdown.

If you relate to one or more of the following statements, then Histamine Nutrients may be helpful for you in supporting healthy histamine levels:

  • I want to walk outside and breathe freely through my nose.
  • I desire feeling comfortable around pets.
  • When mosquitos bite me, I get big, itchy bumps that I scratch profusely.
  • If my skin gets scratched, red lines stay on my skin for quite some time.
  • I want to fall asleep like a healthy person.
  • As a man, I tend to orgasm too quickly.
  • I tend to get irritable or headaches around fragrances.
  • I tend to be more sensitive to EMF and WiFi than others.
  • I have a dirty histamine pathway (DAO, HNMT, NAT2, ALDH, MAOA, MAOB).
  • I have tried, or currently use, Histamine Digest and still experience histamine symptoms.
  • When exercising, I sweat profusely, often getting a red face or ringing in my ears.

The synergistic blend of nutrients found in Histamine Nutrients supports healthy histamine metabolism. It also supports the body’s normal breakdown of histamine’s toxic byproducts.

Customer Review

Histamine Nutrients

My 10 year old son suffers from seasonal discomfort. Since starting him on Histamine Nutrients, he can now play outdoors all day and fall asleep easily. My husband has had support from it as well since taking these, too! I love how you don’t have to take it everyday as well! Definitely recommended for anyone experiencing seasonal discomfort! - Holly

Key Ingredients In Histamine Nutrients

  • DAO2TM (Diamine oxidase): A patented, porcine-derived enzyme. DAO is the enzyme responsible for breaking down histamine in the digestive tract
  • Zinc, Vitamins B1 & B3: Nutrient cofactors for aldehyde metabolism and the ALDH enzyme
  • SAMe: A cofactor for the HNMT enzyme that breaks down histamine throughout the body
  • Alpha Keto-Glutarate: Supports the normal breakdown of ammonia, a toxic byproduct of histamine metabolism
  • PQQ: supports normal breakdown of hydrogen peroxide and aldehydes
  • Vitamin C: stabilizes mast cells to support healthy histamine release
  • Vitamin B6: a cofactor for the DAO enzyme and supports healthy ammonia levels
  • Vitamin B5 (pantothenic acid): a cofactor for the NAT2 enzyme, which metabolizes histamine to acetyl histamine and eliminates it in the urine

Why Histamine Nutrients Works

In order for your body to have healthy histamine levels, you have to provide very specific nutrients. If you are lacking in even just one nutrient, your histamine levels will be problematic for you.

This is likely why histamine intolerance is such a common issue. It just takes one nutrient deficiency.

Here's why.

Histamine is a compound that requires destruction by multiple enzymes. These enzymes require specific nutrients. Think of it like an assembly line. If one worker gets overwhelmed, or doesn't have the right tools for the job, everything gets backed up.

Histamine Nutrients is the first, and likely only, supplement which supports all the histamine breakdown enzymes in your body. All of them. There are five enzymes which break apart histamine and eliminate it from your body. As mentioned before, you have to have ALL 5 enzymes working together simultaneously. If you don’t, you will not achieve healthy histamine levels.

Here are your five histamine breakdown enzymes:

  1. HNMT: this requires SAMe to initiate the first step of histamine breakdown into methylhistamine. HNMT is found heavily in your brain, uterus and liver.
  2. MAOA and MAOB: these two enzymes both require vitamin B2. These two enzymes process the methylhistamine made by HNMT.
  3. ALDH: this enzyme requires zinc, niacin and vitamin B1. This enzyme processes the compounds made by your MAOA, MAOB and DAO enzymes.
  4. DAO: this enzyme requires copper and vitamin B6. This enzyme processes histamine found in the digestive tract, placenta, bladder and many other areas.



It's not that easy.

As these enzymes work in breaking down histamine, they create the toxic compounds of ammonia, hydrogen peroxide, and acetaldehyde. These compounds must be broken down by additional enzymes. These enzymes require alpha keto-glutarate, thiamine and PQQ.

Next time you want to support healthy levels of histamine, and the elimination of the toxic byproducts, take 2 capsules of Histamine Nutrients anytime you need it - day or night. You will notice that it acts quite quickly.

Histamine Nutrients
Supplement Facts

Serving Size: 2 Capsules
Servings Per Container: 30

Vitamin C (as ascorbic acid) 100 mg 111%
Thiamine (as thiamine hydrochloride) 20 mg 1,667%
Riboflavin (as riboflavin 5'-phosphate sodium) 10 mg 769%
Niacin (as nicotinic acid) 25 mg 156%
Vitamin B6 (as pyridoxal 5'-phosphate) 7 mg 412%
Pantothenic Acid (as d-calcium pantothenate) 10 mg 200%
Magnesium (as DiMagnesium Malate)(Albion®) 50 mg 12%
Zinc (as zinc gluconate) 5 mg 45%
Copper (as copper gluconate) 0.5 mg 56%
Histamine Nutrients Blend
Alpha-Ketoglutaric Acid, SAMe (as disulfate ptoluensulfonate), PQQ (as LifePQQTM pyrroloquinoline quinone disodium salt), DAO2TM porcine kidney extract (Diamine Oxidase Activity 15,000 HDU)
259.1 mg *
**Daily Value (DV) not established.

Other Ingredients: vegetarian capsule (hypromellose, water, and gellan gum), ascorbyl palmitate, microcrystalline cellulose and silica.
Albion® is a registered trademark of Balchem Corporation or its subsidiaries.
DAO2TM is a licensed trademark of Diem Direct, LLC used with permission.

    NOT Suitable for Vegetarians or Vegans
  • Delivery Method: Capsules
  • How To Store: Keep tightly closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use Histamine Nutrients

Suggested Use

As needed, take 1-2 capsules with food. Use during the day to support healthy histamine breakdown. Use during the evening to support a healthy onset of sleep. Use as directed by your healthcare professional.

Note: For additional histamine support, consider adding HistaminX to stabilize histamine. To support healthy levels in the digestive system, consider ProBiota HistaminX and/or Histamine Digest.


Consult with your healthcare practitioner prior to use. Do not use if inner tamper seal is damaged

NOT Suitable for

Vegetarians or Vegans

Delivery Method


How to Store

Keep closed in a cool, dry place out of reach by children.

FAQs for Histamine Nutrients

What is the purpose of each ingredient in Histamine Nutrients?

Ingredients Purpose
Vitamin C Supports healthy DAO production, normal histamine breakdown, and normal inflammatory processes
Thiamine Is often depleted in the presence of high aldehyde levels and other histamine byproducts
Niacin Plays a role in increasing the activity of the ALDH enzyme family to support the normal regulation of acetaldehyde concentrations
Vitamin B6 Works with DAO to help support the normal breakdown of histamine
Pantothenic Acid Cofactor for the NAT2 enzyme, which metabolizes histamine to acetylhistamine
Magnesium (as Di-Magnesium Malate) (Albion®) Supports normal glutamate response from ammonia release. Ammonia is released from histamine metabolism
Zinc Cofactor for the ALDH enzyme family
Copper Cofactor for the DAO enzyme
Alpha-Ketoglutaric Acid Supports normal ammonia breakdown, which is created from histamine metabolism
SAMe Cofactor for the HNMT enzyme, which is a major enzyme in histamine breakdown
PQQ Supports healthy oxidative stress responses
DAO (porcine extract) The enzyme that supports healthy breakdown of histamine from food

Why is Histamine Nutrients not suitable for vegans or vegetarians?

Histamine Nutrients contains porcine-derived ingredients.

Which histamine product is right for me?

Check out this Histamine Supplement Comparison Chart..

If you have a question that's not addressed
here, see all frequently asked questions.


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What our customers say

Real reviews from real customers.

Rated 4.8 out of 5 stars
Based on 224 reviews
Total 5 star reviews: 199 Total 4 star reviews: 12 Total 3 star reviews: 6 Total 2 star reviews: 1 Total 1 star reviews: 6
92%would recommend this product
224 reviews
  • ME
    Marie Elena R.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Essential if you live with histamine sensitivity!

    Yes, you can eat foods that are high in histamine -- even with histamine sensitivity. Just make sure to have these on-hand. Have been using them for years to enjoy food and feel supported.

  • AB
    Amanda B.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Histamine Nutrients!

    I've been taking Histamine Nutrients for a few years now to support my body's healthy response during seasonal changes. It has made a noticeable difference in promoting my overall comfort during those times. I'm grateful to have found a safe and effective supplement that works so well for me. Thank you Dr. Ben.

  • JH Profile picture for Julie H.
    Julie H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Histamine Nutrients

    Well I started out just giving this to my son, that hates all things outdoors in the spring. I use it. Now my daughter has discovered Histamine Nutrients and lets just say that bottle is bring fought over. We love this product and try to keep some handy. It makes a huge difference. Thank you Dr. Lynch for creating this!

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