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Seeking Health | L-5-MTHF Lozenge | Vitamins | Supplements
Discontinued

L-5-MTHF Lozenge

4.8
Rated 4.8 out of 5 stars
97 Reviews
SALE $18.95
$17.06
  • Powerful methylation, MTHFR, and homocysteine support
  • Supports healthy mood and cognition
  • Supports healthy genetic expression
DISCONTINUED - This product has been discontinued. For the same serving of high quality folate to support healthy mood and methylation, try L-5-MTHF Capsules - 1,700 mcg DFE (1,000 mcg/1 mg).

Who Needs L-5-MTHF Lozenge

Methylation controls multiple biochemical pathways in your body.

Your genetics, heart health, hormones, sleep, stress, mood, and detoxification depend on healthy methylation.†

Where does your body get the methyl groups needed to carry out methylation? Primarily from folates that come from food and intestinal microbes. Food folates must be first converted into an active form before your body can use them.

Your MTHFR enzyme converts food folates into the active form of folate, methylfolate. This bioavailable form is also known as L-methylfolate. The true biochemical name is L-5-methyltetrahydrofolate (L-5-MTHF).

Over 50 percent of the population is thought to have a genetic mutation in their MTHFR gene. Thus, they may not be achieving adequate methylfolate levels from food alone.†

Because L-5-MTHF bypasses the MTHFR enzyme, it can provide methylation support for those with MTHFR polymorphisms.†

Folate (as bioavailable L-5-MTHF) is:†

  • Easily absorbed and used by cells
  • The predominant form of folate in circulation
  • The only form of folate that can cross the blood-brain barrier
  • Essential for methylation, DNA expression, homocysteine metabolism, and nervous system function

Bioavailability is particularly crucial when working to replenish folate levels. Ideally, methylfolate is also in a format that supports optimal digestion and absorption, such as a lozenge.†

Seeking Health’s L-5-MTHF Lozenge provides potent methylation support in a delicious, well-absorbed lozenge. Each serving contains 1,700 mcg DFE of methylfolate in the bioavailable form of L-5-methyltetrahydrofolate (L-5-MTHF).†

Our L-5-MTHF Lozenge is naturally sweetened with xylitol. These delicious lozenges deliver folate in a form designed to be rapidly digested for optimal absorption.†

The bioactive form of L-methylfolate (L-5-MTHF) is well-utilized in the methylation cycle. It is often the preferred form for those with methylation, homocysteine, or MTHFR gene mutation concerns.†

Mutations in your MTHFR gene can lead to reduced L-methylfolate production and a less functional methylation cycle. Challenges in the methylation cycle may lead to an increase in homocysteine in the body. Cardiovascular and general wellness are dependent upon maintaining homocysteine levels in the normal range.†

Mutations in this gene can also slow your body’s ability to convert folate into its active forms. Thus, a large majority of people may benefit from consuming an L-methylfolate dietary supplement.† The most direct way to support methylation and MTHFR genetic mutations is with L-methylfolate (L-5-MTHF).†

Supplementing with bioavailable L-5-MTHF supports:†

  • Healthy methylation
  • Positive mood
  • Healthy homocysteine levels
  • Nervous system function and development
  • Prevention of neural tube defects during pregnancy
  • Healthy energy production
  • Normal cognitive, memory, and brain function

Methylation has never tasted so good! Get ready for your methylation cycle to fire on all cylinders with Seeking Health’s L-5-MTHF Lozenge.†

Customer Review

Purest Form

Couldn't find a purest form of b9 elsewhere.. Keep it up team!!! ~AB

Key Ingredients In L-5-MTHF Lozenge

  • L-5-MTHF: A superior form of L-methylfolate that readily donates its methyl groups. It aids conversion of the amino acid homocysteine into methionine and supports your entire methylation cycle.†

Why L-5-MTHF Lozenge Works

Folate plays critical roles in methylation. By donating its methyl groups, folate regulates DNA expression and much more. Without sufficient bioavailable folate, your cells cannot effectively express your genes.†

The MTHFR gene converts food folates into methyl folates. However, MTHFR variations and environmental or lifestyle stress can slow this gene down. If the MTHFR gene is slowed, MTHFR enzyme function is also slowed. The result can be a debilitating folate deficiency.

The artificial version of folate, folic acid, is often prescribed to folate-deficient individuals. Supplementation with L-5-MTHF may be more effective than folic acid supplementation at increasing blood folate levels.†

Folic acid is never included in any of our Seeking Health dietary supplements. This artificial version of folate is not well-utilized by the body and can produce adverse effects. Folic acid must go through several enzymatic steps before it is converted into usable methylfolate. Its inefficient chemical structure may even slow down your SLC191A, DHFR, and MTHFR genes to the point of folate deficiency! Folic acid can also block usable folate from entering your cells, further contributing to folate deficiency.†

By supplementing with the natural form of folate as L-5-MTHF, you bypass the MTHFR enzyme. The methylated form, L-5-methylfolate (L-5-MTHF), requires no additional metabolic steps to be used by the body. This is why it is often the preferred choice for those with folate absorption or metabolic defects.†

L-5-MTHF also supports the production of important mood neurotransmitters. These include dopamine, serotonin, melatonin, epinephrine, and norepinephrine. This is how supplementation with L-5-MTHF can help to support a healthy mood.†

Seeking Heath’s L-5-MTHF Lozenge provides a pure, non-racemic form of L-methylfolate. Each delicious, naturally-flavored lozenge offers a potent dose of 1,700 mcg DFE of folate as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt. This superior form supports healthy methylation, mood, and more.†

Because folate needs B12 to support proper methylation, be sure to pair L-5-MTHF Lozenge with a bioactive form of B12, such as Active B12 1000.†

Now you can go about your day with confidence, knowing your methylation cycle is firing on all cylinders!†

L-5-MTHF Lozenge
Supplement Facts

Serving Size: 1 Lozenge
Servings Per Container: 60

AMT %DV
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt] 1,700 mcg DFE (1,000 mcg) 425%

Other Ingredients: Xylitol, ascorbyl palmitate, natural flavors, and silica.

  • Suitable For: Vegetarians and Vegans
  • Delivery Method: Lozenges
  • How To Store: Keep closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, Artificial Flavors, and Artificial Preservatives

How to Use L-5-MTHF Lozenge

Suggested Use

Take 1 capsule daily, or use as directed by your healthcare provider. Do not take within 5 hours of bedtime as it may interfere with sleep.

Warnings

Children and pregnant or lactating women should consult their healthcare professional prior to use. Do not use if tamper seal is damaged. Consult a healthcare professional prior to use if you are taking any medications or if you are undergoing treatment for any medical condition.

FAQs for L-5-MTHF Lozenge

What is the purpose of each ingredient in L-5-MTHF Lozenge?

Ingredients Purpose†
Folate (Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt) Supports a healthy nervous system, methylation, homocysteine recycling, and prenatal regimen along with a healthy diet and lifestyle

How do I know if taking methylfolate (L-5-MTHF) works? How do I improve its utilization?

L-methylfolate (L-5-MTHF) is a superior form of folate that is well-utilized in the body. This is because 80 percent of the human body's folate is in this form.†

L-5-MTHF is the form of folate that is used for methylation. Methylation is simply when one compound donates a methyl group to another compound. By having a methyl group attached, the compound's function changes.†

You know when L-methylfolate works because of how you feel. It's typically very fast to notice if it's working or not.†

According to Dr. Ben Lynch, supplementing with L-methylfolate can support healthy:†

  • Mental clarity
  • Attention and focus
  • Energy production
  • Vision
  • Memory and recall
  • Circulation, especially in the hands and feet
  • Normal blood pressure
  • Normal homocysteine levels

In order for L-methylfolate to work, it requires vitamin B12. Reduced oxidative stress is also needed for L-methylfolate to function.†

L-methylfolate needs the following to support methylation:†

  • Vitamin B12
  • Zinc
  • Glutathione
  • Reduced oxidative stress
  • Functional MTR enzymes

Talk to your qualified healthcare practitioner before starting methylfolate supplementation. A trained health professional will be able to determine the appropriate dosing and whether methylfolate is right for you.

Which folate is right for me?

Click here to view our Folate Supplement Comparison Chart.

Read this blog: The different forms of folate: which one is right for you?

This blog article explains folic acid side effects.

If you have a question that's not addressed
here, see all frequently asked questions.

VIEW ALL FAQS

Do you have Questions
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What our customers say

Real reviews from real customers.

4.8
Rated 4.8 out of 5 stars
Based on 97 reviews
Total 5 star reviews: 87 Total 4 star reviews: 4 Total 3 star reviews: 5 Total 2 star reviews: 1 Total 1 star reviews: 0
96%would recommend these products
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97 reviews
  • C
    Charity
    Verified Buyer
    L-5-MTHF Lozenge
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    L-5-MTHF Lozenge
    I recommend this product
    Rated 5 out of 5 stars
    55 minutes ago
    This Was a Great Product

    A family member has used this product for several years and found it VERY helpful first thing in AM to support folate and methyl group levels and healthy BP. That individual has low stomach acid and found a dose of 75mcg (3/4 of lozenge) to be best on most days. Thus, capsules won't work well or, at best, will be bitter if must be broken and just swallow the powder. Very unhappy to hear lozenges discontinued because of "overlap with other products." Back to Square One.

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  • MS
    Marsha S.
    Verified Buyer
    L-5-MTHF Lozenge
    Reviewing
    L-5-MTHF Lozenge
    I recommend this product
    Rated 5 out of 5 stars
    4 weeks ago
    L 5 MTHF Lozenge

    Very helpful to my health.

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  • SK
    Shirley K.
    Verified Buyer
    L-5-MTHF Lozenge
    Reviewing
    L-5-MTHF Lozenge
    I recommend this product
    Rated 5 out of 5 stars
    4 weeks ago
    Excellent

    Love that these taste great and I can take more or less when natural folate in my diet is lacking. It's often difficult to find the freshest, organic green vegetables to meet my bodies need for high quality folate and having these as a backup is priceless.

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†These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.