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Seeking Health we will be closed on May 27th in observance of the holiday. We will resume normal business hours on May 28th.
Seeking Health we will be closed on May 27th in observance of the holiday. We will resume normal business hours on May 28th.

Optimal Prenatal MF

  • High-strength, methyl-free prenatal
  • Supports healthy immune, spine, and brain development
  • Free of methylated B vitamins, choline, betaine, and inositol (methyl donors)

Who Needs Optimal Prenatal Methyl-Free

Do you get side effects from methylated nutrients?

Some people experience nervousness, headaches, or rapid heartbeat when they take nutrients like methylcobalamin and methylfolate.

Yet, these active forms of vitamin B12 and folate are required for a healthy and successful pregnancy. For women who are considered higher-risk, bioavailable and well-tolerated sources of B12 and folate are absolutely critical.

Optimal Prenatal MF is the first non-methylated prenatal vitamin of its kind. This unique formula provides high-strength nutrition minus the methyl donors.

If you relate to one or more of the following, then Optimal Prenatal MF may be exactly what you’re looking for:

  • I get side effects like nervousness, headaches, or rapid heartbeat when I take methylated nutrients.
  • I have a history of pregnancy complications or preterm births. I want to support a healthy pregnancy.
  • Prior pregnancies have been difficult.
  • I have multiple nutrient deficiencies.
  • I experience significant morning sickness.
  • Currently, I’m trying to get pregnant and I am experiencing difficulties. I want to support healthy fertility.
  • I’m looking for the most comprehensive prenatal formula.
  • I’m tired and breastfeeding. I feel I need more nutritional support for both me and baby.
  • I tend towards feeling blue and tired. Experiencing a positive mood and healthy levels of energy would be lovely.
  • While 6 capsules per serving is a lot, it’s ok for me as I know I’m truly nourishing my developing baby, my placenta and myself. I also know I can take 2 capsules with breakfast, 2 with lunch and the rest with a mid-afternoon snack when I need a pick-me-up.

If a number of those resonated with you, then Optimal Prenatal MF is something that you should seriously consider.

If none of the statements above relate to your current life situation, then Optimal Prenatal MF is most likely not something you need right now.

Most high-strength prenatals on the market contain methylated nutrients. If you’re sensitive to methyl groups, you may have thought you have no options...until now.

Dr. Ben Lynch designed Optimal Prenatal MF as a solution for women needing potent prenatal care, but are sensitive to methyl donors.

(Wondering if you’re sensitive to methylated nutrients? This article will help you determine if you need methyl-free supplements.)

Optimal Prenatal MF includes non-methylated forms of folate and B12. These methyl-free forms take a few additional enzyme steps before they become methyl donors. This slower delivery may provide relief and comfort for women sensitive to methylated nutrients.

Optimal Prenatal MF contains the key nutrients you need for a healthy pregnancy in bioavailable forms, including non-methylated B12 and folate.

  • Folate, as Folinic acid (Calcium folinate)
  • B12, as Adenosylcobalamin and Hydroxocobalamin
  • Vitamin D3, as Cholecalciferol
  • Calcium, as DiCalcium malate
  • Ginger to support digestive comfort
  • 30+ key nutrients to support a healthy pregnancy

This nutrient-dense prenatal multivitamin is free of:

  • Methylated B vitamins
  • Methylcobalamin
  • Methylfolate
  • S-adenosylmethionine (SAMe)
  • Choline
  • Inositol
  • Trimethylglycine (TMG or Betaine)

Like methylfolate and methylcobalamin, folinic acid (folate) and adenosylcobalamin (B12) provide potent, bioavailable prenatal nutrition. These non-methylated forms may be a better option for those who are sensitive to methyl donors.

Optimal Prenatal MF provides crucial support in the following areas of fetal development:

  • Healthy spinal and brain development
  • Normal growth and development
  • Immune system support
  • Healthy antioxidant support
  • Digestive comfort for the mother

Folic acid is never included in any Seeking Health prenatals or dietary supplements. This artificial version of folate is not well utilized by the body. In fact, it can even contribute to folate deficiency!

This prenatal vitamin does not include iron. Some women do not process iron well or do not need iron supplementation. This makes it easy to customize your dosage by supplementing separately with a gentle form of iron. All our Seeking Health prenatal vitamins are gluten-free.

Dr. Lynch recommends starting prenatals for several months before trying to conceive. Optimal Prenatal MF can be taken before, during, and after pregnancy to support:

  • Healthy fertility
  • Pregnancy health
  • Normal fetal development
  • Postpartum recovery
  • Breastfeeding

Optimal Prenatal MF features well-absorbed, chelated minerals and bioavailable vitamins to nourish both of you through this nine-month journey.

Pregnancy is hard enough. You shouldn’t struggle with side effects related to your prenatal. Now, you can provide your body and baby with bioavailable nutrition...without the headache of methyl donors!

Customer Review

Raving about this prenatal

I just have to write a review after consistently using Seeking Health prenatals for about 2 years now. I am so thankful that Dr. Lynch cares so much about these products. This is my first pregnancy, and overall I feel incredible. I fully believe these prenatals have greatly contributed. Time and time again I see them recommended by various naturopaths, chiropractors, functional medicine doctors, etc. That’s a great feeling! I’m a forever customer! ~Braden

Key Ingredients In Optimal Prenatal Methyl-Free

  • Active Folate: As folinic acid, a non-methylated folate. Bioavailable folate is essential for baby’s DNA and RNA synthesis. It is also required for healthy genetic, spinal, and brain development. Folic acid is never included in any of our prenatals or dietary supplements. This artificial version of folate is not well utilized by the body and may even contribute to folate deficiency!
  • Bioavailable B12: Adeno- and Hydroxo-cobalamin are non-methylated forms of vitamin B12. These bioavailable forms support healthy energy production and detoxification. Your body requires vitamin B12 to utilize folate for methylation processes.
  • Vitamin A: This essential vitamin is critical for healthy fetal development. Most prenatals do not use retinyl palmitate, the active form of vitamin A. Dr. Lynch uses this form of vitamin A as it supports healthy eye, skin, bone, and immune system health in both the mother and developing baby.
  • Vitamin D: Supports a healthy immune system, bone growth, and cognition for you and baby.
  • Chelated Minerals: Well-absorbed forms of calcium, magnesium, potassium, and trace minerals support optimal growth and development.

Why Optimal Prenatal Methyl-Free Works

A balanced diet coupled with a high-quality prenatal vitamin can go a long way to promote a healthy pregnancy. Yet most prenatal vitamins on the market contain methylated ingredients like methylfolate...until now.

Optimal Prenatal Methyl-Free is formulated to be free from methylfolate and methylcobalamin. This does not mean it goes without these two essential B vitamins! This product contains non-methylated folate in the form of folinic acid (calcium folinate). It also has non-methylated vitamin B12 in two active forms, hydroxocobalamin and adenosylcobalamin.

Your body converts these non-methylated forms into the forms required for methylation. For example, folinic acid undergoes three enzymatic steps before it is transformed into 5-MTHF (methylfolate). Adenosylcobalamin and hydroxocobalamin are both readily metabolized into cobalamin. The body uses this cobalamin to make methylcobalamin that is needed for methylation.

The additional enzyme steps slow the delivery of methylated nutrients to your system. This can significantly reduce or eliminate side effects in those sensitive to methyl groups.

Even though it does not have a methyl group, folinic acid can still act as a building block for the MTHFR enzyme to make methylfolate. Those with MTHFR genetic mutations can still benefit from this non-methylated form.

Adenosylcobalamin (Adeno B12) assists with energy production in the mitochondria. It does this by acting as a coenzyme that assists in converting cholesterol, other fatty acids, and branched-chain amino acids into ATP. Hydroxocobalamin (Hydroxo B12) helps maintain healthy levels of nitric oxide and cyanide to aid in the normal detoxification of these potential harmful compounds.

These methyl-free forms provide bioavailable and naturally occurring forms of folate and B12 that effectively support methylation. With true, sufficient folate and B12 support healthy fetal development and expression of genetics via methylation.

Say goodbye to the side effects of methyl groups and hello to Optimal Prenatal Methyl-Free!

Optimal Prenatal Methyl-Free
Supplement Facts

Serving Size: 6 Capsules
Servings Per Container: 30

Vitamin A (as beta-carotene and retinyl palmitate) 1,500 mcg RAE 115%
Vitamin C (as ascorbic acid) 350 mg 292%
Vitamin D3 (as cholecalciferol) 100 mcg (4,000 IU) 667%
Vitamin E (as Novatol® d-alpha tocopheryl acid succinate) 130 mg 684%
Thiamin (as thiamine hydrochloride) 5 mg 357%
Riboflavin (as riboflavin 5'-phosphate sodium) 10 mg 625%
Niacin (as niacinamide) 25 mg NE 139%
Vitamin B6 (as pyridoxal 5'-phosphate and pyridoxine hydrochloride) 20 mg 1,000%
Folate (as calcium folinate) 1,360 mcg DFE (800 mcg) 227%
Vitamin B12 (as hydroxocobalmin and adenosylcobalamin) 150 mcg 5,357%
Biotin 500 mcg 1,429%
Pantothenic Acid (as d-calcium pantothenate) 150 mg 2,143%
Calcium (as Di-Calcium Malate)(Albion®️) 400 mg 31%
Iodine (potassium iodide) 250 mcg 86%
Magnesium (as Di-Magnesium Malate)(Albion®️) 250 mg 63%
Zinc (as Zinc Bisglycinate Chelate)(Albion®️) 20 mg 154%
Selenium (as SelenoExcell® High Selenium Yeast) 200 mcg 286%
Copper (as Copper Bisglycinate Chelate) (Albion®️) 0.75 mg 58%
Manganese (as Manganese Bisglycinate Chelate) (Albion®️) 5 mg 192%
Chromium (as Chromium Nicotinate Glycinate Chelate) (Albion®️) 120 mcg 267%
Molybdenum (as Molybdenum Glycinate Chelate) (Albion®️) 100 mcg 200%
Potassium (as Potassium Glycinate Complex) (Albion®️) 99 mg 2%
Ginger Extract (Zingiber officinale)(rhizome)(Ginfort®️) 100 mg **
Milk Thistle Extract (Silybum marianum)(seeds)(80% silymarin) 75 mg **
Coenzyme Q10 (ubidecarenone) 50 mg **
Taurine 50 mg **
Mixed Tocopherols 45 mg **
LifePQQ TM(pyrroloquinoline disodium salt) 10 mg **
Lutein (from marigold extract)(Tagetes erecta)(flowers)(Lutemax®️) 5 mg **
Zeaxanthin (from marigold extract)(Tagetes erecta)(flowers) 5 mg **
Boron (as Bororganic Glycine) (Albion®️) 1 mg **
Vitamin K2 (as menaquinone-7) 100 mcg **
**Daily Value (DV) not established.

Other Ingredients: Vegetarian capsule (hypromellose and water), ascorbyl palmitate, silica, and L-Leucine.
Novatol® is a registered trademark of Archer-Daniels-Midland Company.
Albion®️ is a registered trademarks of Balchem Corporation
Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under US patent 7,947,662.
SelenoExcell® is a registered trademark of Cypress Systems, Inc.
Ginfort® is a trademark of Olene Life Sciences Private Limited. Dolcas Biotech, LLC is the exclusive licensee of Ginfort®.
Lutemax 2020 is a trademark of OmniActive Health Technologies Ltd.

  • Suitable For: Vegetarians
  • Delivery Method: Capsules
  • How To Store: Keep tightly closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, and Artificial Flavors

How to Use Optimal Prenatal Methyl-Free

Suggested Use

As needed, take 6 capsules daily in divided servings with breakfast, lunch, and afternoon snack. Supports healthy fertility, pregnancy, postpartum recovery and breastfeeding.† Do not take within 5 hours of bedtime as it may interfere with sleep. Use as directed by your healthcare professional.


Consult with your healthcare practitioner prior to use. Do not use if inner tamper seal is damaged.

FAQs for Optimal Prenatal Methyl-Free

What is the purpose of each ingredient in Optimal Prenatal Methyl-Free?

Ingredients Purpose
Vitamin A (beta-carotene, retinyl palmitate) Supports healthy vision, mucus membranes, and immune system function
Vitamin D (cholecalciferol) and Vitamin K2 (menaquinone-7) Support healthy calcium utilization, circulation, immune system function, and bone health
Vitamin E (Novatol® d-alpha tocopheryl acid succinate) and Vitamin C (ascorbic acid) Support overall antioxidant levels and a healthy response to oxidative stress
Thiamin (thiamine hydrochloride), Riboflavin (riboflavin 5’-phosphate sodium and riboflavin), Niacin (niacinamide), Vitamin B6 (pyridoxal 5’-phosphate and pyridoxine hydrochloride), Biotin, Folate (as folinic acid (calcium folinate)), Vitamin B12 (hydroxocobalamin and adenosylcobalamin), Pantothenic Acid (d-calcium pantothenate) Support healthy methylation processes, energy production, and genetic development
Iodine (potassium iodide), Zinc (Zinc Bisglycinate Chelate), Selenium (SelenoExcell® High Selenium Yeast), Manganese (Manganese Bisglycinate Chelate), Molybdenum (Molybdenum Glycinate Chelate), Potassium (Potassium Glycinate Complex), Magnesium (DiMagnesium Malate), Calcium (DiCalcium Malate), Copper (Copper Bisglycinate Chelate), Boron (Bororganic Glycine) Essential trace minerals support overall growth and development
Chromium (Chromium Nicotinate Glycinate Chelate) Supports healthy metabolism
Mixed Tocopherols Provides antioxidant support
Lutein and Zeaxanthin (Tagetes erecta) Support eye health and development; Provide antioxidant support
Ginger (Zingiber officinale) Supports stomach comfort
Raspberry leaf Used historically to support uterine strength and comfort during labor
L-Carnosine Supports healthy brain function
Milk Thistle Extract Supports healthy glutathione production and liver health
Coenzyme Q10 (CoQ10, ubidecarenone) Supports healthy heart and cellular stress response
Taurine Supports healthy brain, metabolism, hydration, and liver

Why is Optimal Prenatal Methyl-Free not suitable for vegans?

Optimal Prenatal Methyl-Free is suitable for vegetarians. The vitamin D is derived from sheep’s wool, making Optimal Prenatal Methyl-Free unsuitable for some vegans. This vitamin D, however, is derived from wool that is sheared from live healthy sheep, so no animals are harmed in the process.

Which prenatal is right for me?

Click here to view our Prenatal Supplement Comparison Chart.

This article will help you determine the best prenatal vitamin for you.

This article will help you determine if you need a methyl-free supplement.

If you have a question that's not addressed
here, see all frequently asked questions.


Do you have Questions
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What our customers say

Real reviews from real customers.

Rated 4.9 out of 5 stars
Based on 55 reviews
Total 5 star reviews: 53 Total 4 star reviews: 1 Total 3 star reviews: 1 Total 2 star reviews: 0 Total 1 star reviews: 0
98%would recommend this product
55 reviews
  • SK
    sarah k.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    4 months ago
    My go to

    This is my go to for multivitamins pregnant or not!

  • CW
    Corine W.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    4 months ago
    Good multi vitamin

    I just wish you did not have to take so many pills to get the desired ingredients

  • JS
    Julianne S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7 months ago
    Love these!

    I’m so thankful to have found a MF option!! Methylated vitamins make me SUPER tired all day long, and inositol prolongs my cycles. This prenatal has given me the option to get the best quality without the methylated vitamins! I feel energized and for once found a vitamin that doesn’t give me brain fog!! Hoping they help us when/if we are able to conceive!

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