L-Methylfolate Supplements
L-methylfolate is the most abundant form of folate in your body. It is also referred to as active folate or L-5-MTHF. Other types of folate need to be converted into active forms. People with MTHFR gene variants may not be able to activate folic acid. If you are low on this critical nutrient, your methylation cycle won’t work effectively.
Methylation is essential for regulating gene expression and controlling how your DNA works. L-methylfolate supports healthy red blood cells, mental health, and normal homocysteine levels.
L-methylfolate is the most abundant form of folate in your body. It is also referred to as active folate or L-5-MTHF. Other types of folate need to be converted into active forms. People with MTHFR gene variants may not be able to activate folic acid. If you are low on this critical nutrient, your methylation cycle won’t work effectively.
Methylation is essential for regulating gene expression and controlling how your DNA works. L-methylfolate supports healthy red blood cells, mental health, and normal homocysteine levels. It is found in foods like leafy greens and liver. If you aren’t eating a lot of these, you may benefit from a dietary supplement to support healthy folate levels.†
Seeking Health’s L-methylfolate supplements include L-5-MTHF and Active B12 with L-5-MTHF. You can also get Optimal Prenatal and Optimal Multivitamin, which provide folate along with active vitamin B12 (methylcobalamin), calcium, and other important vitamins and minerals.
Check out this Folate Comparison Chart to select the right folate for you.
Explore L-methylfolate supplementation options below.
If you find that methylated supplements make you feel jittery or upset, use this comparison chart to learn about the differences between methylated and non-methylated products or check out this article.
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NewL-5-MTHF - 8,500 mcg DFE (5,000 mcg/5 mg) - 60 Capsules
5.0Rated 5.0 out of 51 Review Based on 1 reviewFrom $39.95 -
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BOGOL-5-MTHF - 1,700 mcg DFE (1,000 mcg/1 mg) - 60 Capsules - BOGO
4.9Rated 4.9 out of 569 Reviews Based on 69 reviewsFrom $17.95L-5-MTHF Capsules by Seeking Health provide 1,700 mcg DFE (1,000 mcg) of pure non-racemic L-methylfolate, an active coenzyme form of folate. Folate...
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BOGOMultivitamin One - 45 Vegetarian Capsules - BOGO
4.9Rated 4.9 out of 5248 Reviews Based on 248 reviewsFrom $32.95Multivitamin One by Seeking Health provides a wide variety of nutrients in well-absorbed or active forms in a convenient capsule format. Unlike our...
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BOGOPrenatal Essentials Chewable - 60 Tablets - BOGO
4.5Rated 4.5 out of 5188 Reviews Based on 188 reviewsFrom $42.95Prenatal Essentials Chewable offers a specialized prenatal formula designed to help meet the high nutritional needs of women who are pregnant or pr...
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Optimal Man - 120 Capsules
5.0Rated 5.0 out of 55 Reviews Based on 5 reviewsFrom $59.95As a father, your genetics are passed along to your child, as you may well know. But did you know that your genes can change expression based on yo...
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Prenatal Essentials - 60 Capsules
4.9Rated 4.9 out of 5132 Reviews Based on 132 reviewsFrom $32.95Do you need a prenatal supplement without an overload of excess nutrients? Are you a pregnant mother already eating a healthy, well-balanced diet? ...
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Optimal Prenatal Powder – 15 Servings
4.6Rated 4.6 out of 5228 Reviews Based on 228 reviewsFrom $44.96Optimal Prenatal Powder by Seeking Health provides a comprehensive prenatal formula with a unique blend of amino acids, chelated minerals, and vita...
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Optimal Multivitamin Plus - 240 Capsules
5.0Rated 5.0 out of 54 Reviews Based on 4 reviewsFrom $72.95Optimal Multivitamin Plus by Seeking Health is a complete natural daily multivitamin and mineral supplement with active B vitamins and L-5-MTHF. Op...
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Optimal Multivitamin Powder - 30 Servings
0.0From $47.95Optimal Multivitamin Powder by Seeking Health provides bioavailable nutrients in easy-to-absorb forms such as methylfolate and active B12, and mine...
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Best SellerBonus RewardsOptimal Multivitamin Chewable - 60 Tablets
4.4Rated 4.4 out of 57 Reviews Based on 7 reviewsFrom $29.95Optimal Multivitamin Chewable by Seeking Health provides a wide variety of nutrients in well-absorbed or active forms in a great-tasting chewable t...
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Best SellerOptimal Multivitamin - 240 Capsules
5.0Rated 5.0 out of 55 Reviews Based on 5 reviewsFrom $59.95Optimal Multivitamin by Seeking Health is a complete daily multivitamin and mineral supplement containing more than 50 nutritional ingredients, all...
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Multivitamin with Iron - 120 Capsules
4.8Rated 4.8 out of 583 Reviews Based on 83 reviewsFrom $32.95Multivitamin with Iron by Seeking Health is a well-rounded daily multivitamin and mineral supplement with high-potency gentle iron and active B vit...
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Best SellerOptimal Prenatal - 240 Capsules
4.8Rated 4.8 out of 5700 Reviews Based on 700 reviewsFrom $59.95Optimal Prenatal capsules by Seeking Health provide a comprehensive prenatal formula with a unique blend of amino acids, chelated minerals, and vit...
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L-5-MTHF Lozenge - 60 Lozenges
0.0From $18.95L-5-MTHF Lozenges by Seeking Health provide 1,700 mcg DFE (1,000 mcg) of pure non-racemic l-methylfolate, a coenzyme form of folate, in a naturally...
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Kids Multivitamin - 180 Capsules
4.8Rated 4.8 out of 5148 Reviews Based on 148 reviewsFrom $32.95Kids Multivitamin by Seeking Health is a comprehensive multivitamin and mineral supplement that is specifically designed to support the nutritional...
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Best SellerHomocysteX Plus - 60 Capsules
4.9Rated 4.9 out of 5195 Reviews Based on 195 reviewsFrom $32.95HomocysteX Plus by Seeking Health supplies bioactive forms of four essential B-vitamins together with betaine (also known as trimethylglycine or TM...
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Best SellerB Complex Plus - 100 Capsules
4.9Rated 4.9 out of 5258 Reviews Based on 258 reviewsFrom $27.95B Complex Plus by Seeking Health provides eight B vitamins with active forms of folate, vitamin B12, riboflavin, and B6. This complex also contains...
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Best SellerActive B12 with L-5-MTHF - 60 Lozenges
4.9Rated 4.9 out of 5515 Reviews Based on 515 reviewsFrom $21.95Active B12 with L-5-MTHF Lozenges by Seeking Health provide 1,360 mcg DFE (800 mcg) of pure non-racemic L-methylfolate in an easy-to deliver lozeng...
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Best SellerDirty Genes by Dr. Ben Lynch
4.9Rated 4.9 out of 546 Reviews Based on 46 reviewsFrom $20.00Instant National Bestseller After suffering for years with unexplainable health issues, Dr. Ben Lynch discovered the root cause—“dirty” genes. Gene...
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