Skip to content
PEMT Support Bundle

See what's included?

Supplement bottle labeled 'Bile Nutrients' by Seeking Health on a white background
164 Reviews

Bile Nutrients
Supplement bottle labeled 'Liver Nutrients' by Seeking Health on a white background | AB-1 | AB-2
387 Reviews

Liver Nutrients
Supplement bottle labeled 'Optimal PC' by Seeking Health on a white background
186 Reviews

Optimal PC
Ox Bile
266 Reviews

Ox Bile

PEMT Support Bundle

You have a PEMT variant. Your liver needs a different kind of support.

If you read this and thought, “That’s me,” this bundle was built for you.

PEMT variants can reduce your body’s ability to make phosphatidylcholine — a molecule your liver depends on for healthy bile, fat digestion, and cell membrane integrity. When PC runs low, bile gets thick, fat sits instead of moving, and your liver’s workload backs up.

This bundle is designed to supply your liver with the phosphatidylcholine, bile support, and detox cofactors it needs — rather than depending entirely on PEMT to make them.†
$138
$138 - $138
$138
$110.40
$110.40 - $110.40
$110.40

See what's included?

Supplement bottle labeled 'Bile Nutrients' by Seeking Health on a white background
164 Reviews

Bile Nutrients
Supplement bottle labeled 'Liver Nutrients' by Seeking Health on a white background | AB-1 | AB-2
387 Reviews

Liver Nutrients
Supplement bottle labeled 'Optimal PC' by Seeking Health on a white background
186 Reviews

Optimal PC
Ox Bile
266 Reviews

Ox Bile
Third Party Tested Third Party Tested
High End Ingredients High End Ingredients
60-day Return Policy 60-day Return Policy
Free Shipping Free Shipping

Or Choose Individual Products

Optimal PC
4.9
Rated 4.9 out of 5 stars
186 Reviews
| Review Summary

Optimal PC

Direct phosphatidylcholine support for membranes and bile†
$47

What it does for PEMT / Liver & Bile

Phosphatidylcholine (PC) is a primary building block of every cell membrane in your body — but it’s especially critical for liver cells and bile. Your liver uses PC to package cholesterol and fats into bile so they can be excreted. Low PC can lead to thick, sludgy bile that doesn’t flow well. PC also helps protect and nourish liver cell membranes from damage caused by toxins, alcohol, and medications.†

When to take

With meals, especially meals containing fat. PC is fat-soluble and absorbs best alongside dietary fats. Splitting doses across 2–3 meals is ideal.

How to take

Follow label dosing. Softgels can be swallowed whole with food. Some people open capsules and mix the contents into food or smoothies if they have trouble swallowing pills.

Signs you may be taking too little

Sluggish digestion, especially fatty foods. Feeling heavy or nauseated after meals. Recurring skin issues. Bile that is thick or sludgy on imaging. Liver markers not benefiting despite other interventions.

Signs you may be taking too much

PC is generally very well tolerated, but some people experience mild GI upset, fishy burps, or loose stools at higher doses. These are not dangerous — just back off slightly until comfortable.
Bile Nutrients
4.7
Rated 4.7 out of 5 stars
164 Reviews
| Review Summary

Bile Nutrients

Supports the full journey of bile — from liver to gallbladder to intestine†
$42

What it does for PEMT / Liver & Bile

This formula supports the full journey of bile — from production in the liver, to storage in the gallbladder, to release into the intestine. It includes ingredients like taurine (which conjugates bile acids), betaine (thins bile), and herbs that stimulate bile flow (cholagogues). Think of it as keeping the whole plumbing system moving smoothly.†

When to take

15–20 minutes before meals, especially meals containing fat. This primes your system to release bile when the food arrives. Some people also benefit from a dose before bed to support overnight liver processing.†

How to take

Follow label dosing. Taking it slightly before eating (rather than with food) gives the ingredients time to stimulate bile production and flow so you’re ready to digest.†

Signs you may be taking too little

Bloating, gas, or discomfort after fatty meals. Feeling like food “sits” in your stomach. Pale or clay-colored stools (indicates bile isn’t reaching the intestine). Constipation. Nausea after eating.

Signs you may be taking too much

Loose stools or diarrhea — bile is a natural laxative, so too much flow will speed things up. Stomach cramping or urgency after meals. Bright yellow/orange loose stools specifically suggest excess bile reaching the colon. Back off the dose or skip the pre-meal timing.
Liver Nutrients
4.9
Rated 4.9 out of 5 stars
387 Reviews
| Review Summary

Liver Nutrients

Methylation and antioxidant cofactors to give PEMT its tools†
$29

What it does for PEMT / Liver & Bile

Your liver performs over 500 functions — it needs a lot of raw materials. This formula typically provides methylation support (B vitamins, folate), antioxidant support (like milk thistle, NAC, or alpha-lipoic acid), and cofactors for the liver’s detoxification pathways (Phase I and Phase II). It’s designed to support normal liver function for individuals navigating common environmental and lifestyle demands, such as toxin exposure, alcohol, or metabolic stress.†

When to take

With food, typically morning or midday. The B vitamins can be energizing, so avoid evening dosing if you’re sensitive. Consistency matters more than perfect timing — your liver works 24/7.

How to take

Follow label dosing. If you’re new to liver support or know you have a high toxin burden, consider starting at half the dose for the first week. Supporting detox pathways can mobilize stored toxins, and you want to go slowly.†

Signs you may be taking too little

Fatigue despite adequate sleep. Sluggish recovery from alcohol or medications. Skin breakouts, rashes, or dullness. Hormonal imbalances (the liver clears excess hormones). Chemical or fragrance sensitivities. Elevated liver enzymes on bloodwork.

Signs you may be taking too much

Detox-like symptoms — headaches, fatigue, brain fog, skin breakouts, or feeling “flu-ish.” This usually means you’re mobilizing toxins faster than you can clear them. It’s not dangerous, but uncomfortable. Reduce the dose, increase hydration and electrolytes, and consider adding a binder (like activated charcoal or chlorella, taken away from other supplements†).
Ox Bile
4.8
Rated 4.8 out of 5 stars
266 Reviews
| Review Summary

Ox Bile

Supplemental bile salts on demand — essential if you’re missing a gallbladder†
$20

What it does for PEMT / Liver & Bile

This is actual bile — supplemental bile salts derived from oxen. It directly supports what your body may not be producing or releasing adequately. Essential for anyone without a gallbladder (since there’s no longer a reservoir to store and concentrate bile). Also helpful for those wanting to support healthy bile production, or difficulty digesting fats even with gallbladder intact.†

When to take

With meals containing fat — this is non-negotiable. Ox bile has no purpose without fat to emulsify. Take it at the start of your meal or halfway through. No need to take with fat-free meals.

How to take

Follow label dosing — 125 mg is a moderate starting dose. Swallow with food. You may need to adjust based on the fat content of your meal (more fat = potentially more bile needed). Some people take 1 capsule with lighter meals and 2 with heavier, fattier meals.

Signs you may be taking too little

Greasy, floating, or pale stools (fat isn’t being absorbed). Bloating or nausea after fatty foods. Diarrhea specifically after high-fat meals. Deficiencies in fat-soluble vitamins (A, D, E, K) over time. Feeling like fat “doesn’t agree with you.”

Signs you may be taking too much

Loose stools, diarrhea, or urgency — especially bright yellow/orange stools, which indicate excess bile. Stomach cramping or burning sensation. If fat-containing meals suddenly send you running to the bathroom, you’ve likely overshot. Reduce to a lower dose or skip with lighter meals.

What This BundleHelps Address

  • Optimal PC — direct phosphatidylcholine support†
  • Bile Nutrients — supports bile flowing from liver to intestine†
  • Liver Nutrients — methylation and antioxidant cofactors
  • Ox Bile 125 — supplemental bile for fat digestion†

It’s about giving your liver what PEMT can’t fully provide on its own — so digestion, detox, and daily energy can work the way they’re supposed to.†

What Our Customers Say

Kelsey S.
Gallbladder Support
I've been experiencing nausea on and off for over a year due to my gallbladder. I've been taking several supplements but I needed more help, and decided to try this. Since starting optimal PC, I have noticed a healthy response to my nausea and gallbladder flares.I am SO grateful!! It seems to have been my missing puzzle piece.
Terri
Happy liver
Helps support a healthy liver since having my gallbladder removed.
Ellen
Great for liver health and bile flow
Bile flow is so needful in the body's ability to detoxify, and we have more and more to detoxify in our world. I trust Seeking Health to source ox bile ethically and responsibly from clean sources.
Lyra R.
The only ox bile for me!
I always have this in my cabinet. I really appreciate that it's a 125mg capsule with only ox bile. I do have a hard time processing fats, but not with these! Really helps.
Penny
Bile Nutrients
I was experiencing occasional digestive discomfort, and this product was very helpful in supporting a calming effect

You’re in the right place

When the foundation is supported
everything works better
Start with daily, genetics-informed nutrients.

Stay up to date on our latest product releases, events, and more!

Receive 10% off your order when you download our App!