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30 Capsules

Key Benefits and Actions*

  • May help support healthy mood
  • May help support healthy connective tissues
  • May help support normal glutathione levels and liver health
  • May help support healthy methylation processes

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Availability: In stock

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Suitable for Vegans and Vegetarians

Free of:

Dairy, Egg, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, Soy

SAMe by Seeking Health provides 250 mg of S-adenosyl-L-methionine (SAMe) in each protective, acid-resistant vegetarian capsule. To optimize stability and prevent degradation on exposure to environmental factors, each capsule is protected from moisture and air in a pop-out blister pack.*

SAMe is the body's main methyl donor - it is found in nearly every tissue and fluid in the human body. SAMe is naturally produced from the amino acid methionine and ATP. It is involved in the synthesis and regulation of chemicals in the brain, the maintenance of healthy cell membranes, the ATP cycle, and both methylation and transsulfuration pathways. As a sulfur-containing compound, SAMe is also important for normal production of glutathione, cysteine and taurine and may therefore be implicated in maintaining healthy liver function. Due to its role in supporting healthy synthesis of connective tissues, SAMe may also help support bone and joint health.*

Suggested Use

Take one capsule 45 minutes before or 60 minutes after a meal or as recommended by your healthcare professional. Taking away from food increases absorption.


Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Consult with a healthcare professional prior to use if you have any medical conditions. Individuals taking medications of any kind, especially for depression or anxiety, or MAOIs, should consult with a healthcare provider prior to taking this supplement.

Serving Size: 1
Servings Per Container: 30

Supplement Facts

SAMe (S-adenosyl-L-methionine) 250 mg **
% DV (Daily Value) based on standard 2,000 calorie daily intake
**Daily Value not established

Other Ingredients: HPMC (acid-resistant capsule), calcium chloride anhydrous, ascorbyl palmitate, calcium oxide, silica, and microcrystalline cellulose.

Additional Info
Additional Info
Knowledge Base Find product FAQ and more! Click here.
Cost Per Serving $1.00
Delivery Method Vegetarian Capsule
Capsule Size 0
Storage Keep closed in a cool, dry place out of reach by children. Keep out of direct sunlight. Pop each capsule out of the blister pack only as needed to reduce exposure of the capsules to oxygen and light. Take immediately after removing from packaging.
Age Suitability Adult
Manufactured In USA
Case Quantity 12
Dimensions (in.) Length: 1.25 / Width: 5.75 / Height: 4
Weight (lb.) 0.1000
Barcode 798295549181
Return Policy 30 Day Returns ― Learn more about our Return Policy.
Customer Reviews (9)
Great product
My naturopathic MD recommended this supplement and it has been excellent. Review by Nicole (Posted on 1/18/2018)
Improved sleep/wake cycle
I don't know why, but since stared taking this, my sleep/wake cycle is now normal, and had been to many doctors for sleep issues, and nothing has ever fixed it at all. And like magic, now I sleep at night and can maintain being awake during the day. A miracle for me. Occasionally I still have dips of energy and need to nap, but can still maintain a normal sleep/wake cycle even with a nap, it so nice to be a day person again and have a social life back. Again, don't know how it worked out, but I'm glad. I do have MTHFR which is why I started taking this to start with. But I certainly don't ever want to be without this supplement again!!! Review by KristiM (Posted on 11/24/2017)
Finally Some Sleep!
I started taking the SAMe and it has helped me stay asleep longer. I was taking a tablet before with no success, and wanted to try Dr. Lynch's. It's worth every penny! Review by Jessica (Posted on 10/30/2017)
Blister packed protection! Additionally I like the low dose. Most store products are 400 mg and I do like the option to titrate up if necessary. Thank you for the wonderful supplement line options for nutrigenomic health! Review by Edr1976 (Posted on 5/29/2017)
Healthier Alternative To Xanax
I have been taking SAMe at night and Magnesium Plus during the day and have consistently slept better but today after feeling unusually anxious for the majority of the day, I tried an extra SAMe and within 10-15 minutes, I felt like the blanket was lifted and the anxiety was so much better! I love the quality and research that goes in to every product here! Review by Kristi (Posted on 5/23/2017)
Very good.
This is a great supplement for those who have high histamine level, but be careful about potassium and b-vitamins. Many Sam-e supplements have toxic enteric coatings, This is one of the few which has a non-toxic capsule. Review by Michal (Posted on 5/16/2017)
Great Product
I have been taking Seeking Health supplements for over a year. Dr. Lynch has high quality products. I take this because of my MTHFR C677T. This is great support for mythelation. I can tell when I forget to take it because I don't feel as well. Review by Diane (Posted on 4/20/2017)
Immediate Difference
Within 2 days I felt a huge improvement. It was like the clouds finally lifted after many months of general sadness and low energy. I have high blood histamine levels and am an under-methylator so this what just what I needed. Review by AKS (Posted on 4/14/2017)
great results
Started taking this a year ago on advice from my physician - when I run out I notice i'm in need and this supplement version seems to be the one my body likes the best. Review by anne (Posted on 3/14/2017)
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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