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Active B12 1000

60 Lozenges

Key Benefits and Actions*

  • May help support the normal conversion of homocysteine to methionine
  • May help support healthy methylation and metabolism
  • May help support cognitive health
  • May help support healthy energy levels

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Availability: In stock

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Suitable for Vegans and Vegetarians

Free of:

Dairy, Egg, Fish, Shellfish, Tree Nuts, Peanuts, Wheat, Soy, Gluten, GMO

Active B12 1000 by Seeking Health provides two active “coenzyme” forms of vitamin B12, methylcobalamin and adenosylcobalamin, in a in a lower dose of 1,000 mcg (1 mg) per lozenge. As “coenzyme” forms, methylcobalamin and adenosylcobalamin are the forms required by certain B12-dependent enzymes and reactions within the body. Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the conversion of homocysteine to methionine. Methionine is required for the formation of SAMe (S-adenosylmethionine), an important methyl donor.*

Vitamin B12 is naturally present in seafood, shellfish, liver, eggs and dairy products. It may be harder for vegetarians and vegans to meet their daily needs for vitamin B12 from food sources without relying on supplements or fortified foods.*

As each individual may have different needs for vitamin B12, the dose of this vitamin contained in Active B12 1000 may not be ideal for everyone. Working with a qualified healthcare professional is the best way determine the appropriate dose for your individual needs. The lozenges can be broken down into halves or quarters if a lower dose is desired.

For a higher (5,000 mcg) dose of vitamin B12 per lozenge, consider our Active B12 5000. For a similar product without the methylcobalamin, consider our Adeno B12. For vitamin B12 in the form of hydroxocobalamin, consider our Hydroxo B12.

Suggested Use

Take 1 lozenge daily or as directed by your healthcare professional. Lozenge may be broken into smaller pieces if lower dosage is desired.


Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Consult with a healthcare professional before use if you are using antibiotics or other medications.

Serving Size: 1 Lozenge
Servings Per Container: 60

Supplement Facts

Vitamin B12 (80% as methylcobalamin and 20% as adenosylcobalamin) 1000 mcg 41,667%
% DV (Daily Value) based on standard 2,000 calorie daily intake
**Daily Value not established

Other Ingredients: Xylitol, ascorbyl palmitate, natural orange flavor, and silica.

Additional Info
Additional Info
Learning Center Find product FAQ and more! Click here.
Cost Per Serving $0.17
Delivery Method Lozenge
Tablet Size 11/32" round tablet
Storage Keep closed in a cool, dry place out of reach by children.
Age Suitability Adult
Manufactured In USA
Case Quantity 24
Dimensions (in.) Length: 1.875 / Width: 1.875 / Height: 3.25
Weight (lb.) 0.0500
Barcode 710465148765
Return Policy 30 Day Returns ― Learn more about our Return Policy.
Customer Reviews (9)
Nice price for a quick b12 increase
This was a great addition to my sublingual folate prescription. Review by Rhanda (Posted on 9/3/2018)
Feeling so much better
If you are in need of B12 supplementation, this is the one for you. I feel so much better now that I am getting what my body needs. Thank you Seeking Health! Review by Vic (Posted on 7/27/2018)
Excellent product
My friend/nutritionist ordered this for me and it has been great! I struggle with texture and taste issues but these are not bad at all! I have noticed a difference in my energy levels, as a pregnant mom of 4 this is huge! Review by Chasity (Posted on 7/17/2018)
Great b12 for my son
Love this supplement and have looked at A LOT of different brands. Most other companies have fillers but not this one. It's pure, easy to take and gets the job done. Most importantly, no complaints from my 7 year old. Score! Review by T. (Posted on 7/2/2018)
Most Effective B12
I've used a number of brands of sublingual B-12. Some do next to nothing, while other seem to function somewhat when taken at higher doses.

The Seeking Health Active B12 is the most potent brand of B12 I have tried. In fact if your methylation is limping along, you may want to start with a small fraction of one of these tablets for awhile. And watch for potassium deficiency symptoms as your methylation starts to function correctly again and your potassium is used up making new cells. It can be quite uncomfortable if you don't know what's going on. But most people with just borderline non-functional methylation probably don't have to be this cautious. I have been almost bedbound for years with lyme and CFS, so starting up my methylation has been challenging, to say the least.

Anyway, great product, most effective on the market!
Review by Steve (Posted on 4/1/2018)
My doctor recommended this site for specifically this product and the blood work has already seen an improvement - thank you !! Review by Kim (Posted on 3/20/2018)
Best b12 around
Really happy with these, great absorption, will keep using! Review by Christopher (Posted on 3/20/2018)
Finally A B12 That Works!
My health care provider said I needed vitamin B12 supplementation. I took two different products at separate times suggested by my provider, but unfortunately, my body could not handle either. After reading about the purity of Seeking Health's products and discovering their B12 is both vegan and vegetarian, I placed an order, hoping for the best. I'm glad I did! I feel so much better. I'm eager to see my tests results. I'm positive my lab work has improved. Review by Elaine (Posted on 4/25/2017)
My Best methylation support
As much as I may need more, I prefer this combination.

It makes me feel safe and mainly relax and helps with concentration.

I take as I need not on regular basis.
Review by Maryar (Posted on 3/6/2017)
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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