Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars201 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
ImprovedAshwagandha
SHOP NOW $254.9Rated 4.9 out of 5 stars161 ReviewsFrom $25This targeted formulation combines clinically-studied Shoden® Ashwagandha, magnesium malate, and Ginfort® ginger to help you maintain a balanced i...
View full detailsOriginal price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50(Save 67%)$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,617 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
SHOP NOW $434.8Rated 4.8 out of 5 stars158 ReviewsFrom $43Key Benefits:† DIM Supplement Supports healthy liver metabolism of estrogens Glutathione added to support healthy estrogen detoxification Support...
View full detailsOriginal price $43 - Original price $258Original price $43 - Original price $258Original price $129$129$43.00 - $219.30(Save 67%)$43.00 - $219.30Original price $43.00 - Original price $258.00Original price $43.00 - Original price $258.00Original price $129.00$43.00 - $219.30$43.00 - $219.30Current price $43$43.00 - $219.30Current price $43 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars77 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars193 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars201 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
ImprovedAshwagandha
SHOP NOW $254.9Rated 4.9 out of 5 stars161 ReviewsFrom $25This targeted formulation combines clinically-studied Shoden® Ashwagandha, magnesium malate, and Ginfort® ginger to help you maintain a balanced i...
View full detailsOriginal price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50(Save 67%)$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,617 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
SHOP NOW $434.8Rated 4.8 out of 5 stars158 ReviewsFrom $43Key Benefits:† DIM Supplement Supports healthy liver metabolism of estrogens Glutathione added to support healthy estrogen detoxification Support...
View full detailsOriginal price $43 - Original price $258Original price $43 - Original price $258Original price $129$129$43.00 - $219.30(Save 67%)$43.00 - $219.30Original price $43.00 - Original price $258.00Original price $43.00 - Original price $258.00Original price $129.00$43.00 - $219.30$43.00 - $219.30Current price $43$43.00 - $219.30Current price $43 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars77 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars193 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
-
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars201 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
ImprovedAshwagandha
SHOP NOW $254.9Rated 4.9 out of 5 stars161 ReviewsFrom $25This targeted formulation combines clinically-studied Shoden® Ashwagandha, magnesium malate, and Ginfort® ginger to help you maintain a balanced i...
View full detailsOriginal price $25 - Original price $150Original price $25 - Original price $150Original price $75$75$25.00 - $127.50(Save 67%)$25.00 - $127.50Original price $25.00 - Original price $150.00Original price $25.00 - Original price $150.00Original price $75.00$25.00 - $127.50$25.00 - $127.50Current price $25$25.00 - $127.50Current price $25 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,617 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
SHOP NOW $434.8Rated 4.8 out of 5 stars158 ReviewsFrom $43Key Benefits:† DIM Supplement Supports healthy liver metabolism of estrogens Glutathione added to support healthy estrogen detoxification Support...
View full detailsOriginal price $43 - Original price $258Original price $43 - Original price $258Original price $129$129$43.00 - $219.30(Save 67%)$43.00 - $219.30Original price $43.00 - Original price $258.00Original price $43.00 - Original price $258.00Original price $129.00$43.00 - $219.30$43.00 - $219.30Current price $43$43.00 - $219.30Current price $43 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars77 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars193 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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