Dirty Genes® - COMT Slow Support
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
The COMT gene makes an enzyme that regulates neurotransmitters and hormones. It plays a big role in how your body breaks down estrogen and uses other compounds. Slow COMT may lead to high estrogen or too many neurotransmitters (dopamine, norepinephrine, and epinephrine). This could make you feel irritable, tense, or unable to relax. You might not sleep well and you might even have detoxification or hormone problems.
Slow COMT activity may mean that you don’t have enough SAMe or too much homocysteine. Nutrients that support a balanced COMT gene include vitamin B12, other B vitamins, folate, and magnesium. Your MTHFR gene works closely with COMT, so you also need nutrients for methylation, like betaine and SAMe.
To support your slow COMT gene, you need supplementation that promotes the optimal way your gene should function. Hydrox-Adeno B12 and Folinic Acid provide bioavailable sources of vitamin B12 and folate in methyl-free versions, which might be easier to tolerate if you have a sensitive brain.
Explore other supportive nutrients for your COMT gene below, like Optimal Magnesium , Adrenal Support, or Optimal Sleep.
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Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
SHOP NOW $454.8Rated 4.8 out of 5 stars219 ReviewsFrom $45Provides seasonal comfort and healthy immune responses with plant compounds, bioflavonoids, and enzymes that work together to promote healthy infl...
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Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
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Best SellerImprovedOptimal Electrolyte
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Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
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Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
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Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars204 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
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Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
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Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars189 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
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Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
SHOP NOW $454.8Rated 4.8 out of 5 stars219 ReviewsFrom $45Provides seasonal comfort and healthy immune responses with plant compounds, bioflavonoids, and enzymes that work together to promote healthy infl...
View full detailsOriginal price $45 - Original price $270Original price $45 - Original price $270Original price $135$135$45.00 - $229.50(Save 67%)$45.00 - $229.50Original price $45.00 - Original price $270.00Original price $45.00 - Original price $270.00Original price $135.00$45.00 - $229.50$45.00 - $229.50Current price $45$45.00 - $229.50Current price $45 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,615 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars74 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars204 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars200 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars189 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
SHOP NOW $454.8Rated 4.8 out of 5 stars219 ReviewsFrom $45Provides seasonal comfort and healthy immune responses with plant compounds, bioflavonoids, and enzymes that work together to promote healthy infl...
View full detailsOriginal price $45 - Original price $270Original price $45 - Original price $270Original price $135$135$45.00 - $229.50(Save 67%)$45.00 - $229.50Original price $45.00 - Original price $270.00Original price $45.00 - Original price $270.00Original price $135.00$45.00 - $229.50$45.00 - $229.50Current price $45$45.00 - $229.50Current price $45 -
Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!†
Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.†
Best SellerImprovedOptimal Electrolyte
SHOP NOW $384.6Rated 4.6 out of 5 stars1,615 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, H...
View full detailsOriginal price $38 - Original price $228Original price $38 - Original price $228Original price $114$114$38.00 - $193.80(Save 67%)$38.00 - $193.80Original price $38.00 - Original price $228.00Original price $38.00 - Original price $228.00Original price $114.00$38.00 - $193.80$38.00 - $193.80Current price $38$38.00 - $193.80Current price $38 -
Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
SHOP NOW $304.5Rated 4.5 out of 5 stars74 ReviewsFrom $30Great-tasting, kid-approved, sugar free comprehensive methyl-free multivitamin for kids 4 years old and up. Contains folinic acid.† The types ...
View full detailsOriginal price $30 - Original price $180Original price $30 - Original price $180Original price $90$90$30.00 - $153.00(Save 67%)$30.00 - $153.00Original price $30.00 - Original price $180.00Original price $30.00 - Original price $180.00Original price $90.00$30.00 - $153.00$30.00 - $153.00Current price $30$30.00 - $153.00Current price $30 -
Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid.†
Folinic Acid —Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
SHOP NOW $204.8Rated 4.8 out of 5 stars204 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
View full detailsOriginal price $20 - Original price $120Original price $20 - Original price $120Original price $60$60$20.00 - $102.00(Save 67%)$20.00 - $102.00Original price $20.00 - Original price $120.00Original price $20.00 - Original price $120.00Original price $60.00$20.00 - $102.00$20.00 - $102.00Current price $20$20.00 - $102.00Current price $20 -
Help sustain healthy magnesium levels to support healthy sleep and feelings of relaxation and calm with Magnesium Plus†
Magnesium Plus—Provides two bioavailable forms of magnesium (malate and glycinate) plus the active form of vitamin B6 to enhance absorption in support of natural energy, relaxation, and GI comfort.†
Magnesium Plus
SHOP NOW $284.9Rated 4.9 out of 5 stars200 ReviewsFrom $28Key Benefits and Actions† Magnesium plus vitamin B6 for enhanced absorption and utilization Well-absorbed malate and glycinate forms of magnesiu...
View full detailsOriginal price $28 - Original price $168Original price $28 - Original price $168Original price $84$84$28.00 - $142.80(Save 67%)$28.00 - $142.80Original price $28.00 - Original price $168.00Original price $28.00 - Original price $168.00Original price $84.00$28.00 - $142.80$28.00 - $142.80Current price $28$28.00 - $142.80Current price $28 -
Support healthy magnesium levels for your hormones, energy, bones, blood sugar, mood, and muscles with Magnesium Malate Powder!†
Magnesium Malate Powder—A potent 500 mg serving of dimagnesium malate, a well-tolerated form of magnesium that binds to malate for superior absorption and energy support.†
Magnesium Malate Powder
SHOP NOW $224.7Rated 4.7 out of 5 stars189 ReviewsFrom $22Key Benefits and Actions† Potent, powdered magnesium supplement Well-absorbed dimalate form of magnesium Supports healthy energy, muscles, nerve...
View full detailsOriginal price $22 - Original price $132Original price $22 - Original price $132Original price $66$66$22.00 - $112.20(Save 67%)$22.00 - $112.20Original price $22.00 - Original price $132.00Original price $22.00 - Original price $132.00Original price $66.00$22.00 - $112.20$22.00 - $112.20Current price $22$22.00 - $112.20Current price $22
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