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Methylation Supplements

Support the building blocks of life and overall health and well-being with Seeking Health's methylation supplements!.

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All Products

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  • Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!

    Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.

    Methyl B12 with L-Methylfolate
    Best Seller
    HSA / FSA

    Methyl B12 with L-Methylfolate

    4.9
    Rated 4.9 out of 5 stars
    885 Reviews
    SHOP NOW $27
    From $27

    A delicious, fast-absorbing lozenge that bypasses genetic bottlenecks to support healthy methylation, balanced homocysteine levels, mental clarity...

    View full details
    Original price $27 - Original price $162
    Original price $27 - Original price $162
    Original price $81
    $81
    $27.00 - $137.70
    Save 67%
    $27.00 - $137.70
    $27.00 - $137.70
    Current price $27
  • Gently support healthy blood iron levels with well-tolerated ingredients in Iron with Cofactors.

    Iron with Cofactors—provides a well-tolerated form of iron (ferric glycinate) along with targeted nutrients, including vitamins A, B12, and C, that help to absorb and utilize the iron.

    Supplement bottle labeled 'Iron with Cofactors' by Seeking Health on a white background

    Iron with Cofactors

    5.0
    Rated 5.0 out of 5 stars
    205 Reviews
    SHOP NOW $22
    From $22

    Key Benefits and Actions† Gentle iron complex supports optimal absorption Well-tolerated form of iron; Easy on the stomach Cofactor nutrients su...

    View full details
    Original price $22 - Original price $132
    Original price $22 - Original price $132
    Original price $66
    $66
    $22.00 - $112.20
    Save 67%
    $22.00 - $112.20
    $22.00 - $112.20
    Current price $22
  • Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!

    Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.

    Hydroxo B12 with Folinic Acid | AB-1
    Best Seller

    Hydroxo B12 with Folinic Acid

    4.9
    Rated 4.9 out of 5 stars
    305 Reviews
    SHOP NOW $27
    From $27

    Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...

    View full details
    Original price $27 - Original price $162
    Original price $27 - Original price $162
    Original price $81
    $81
    $27.00 - $137.70
    Save 67%
    $27.00 - $137.70
    $27.00 - $137.70
    Current price $27
  • Support the body’s normal antioxidant protection and healthy detoxification conveniently on the go with Glutathione with Cofactors Lozenges!

    Glutathione with Cofactors Lozenges—A great-tasting and effective glutathione lozenge with essential cofactors supporting the normal neutralization of toxic compounds that are generated by liver detoxification.

    Supplement bottle labeled 'Glutathione with Cofactors' by Seeking Health on a white background
    Best Seller
    HSA / FSA
    Essential for Spring

    Glutathione with Cofactors Lozenges ( formerly Glutathione Plus Lozenge )

    4.8
    Rated 4.8 out of 5 stars
    214 Reviews
    SHOP NOW $50
    From $50

    Delivers fast-acting, delicious antioxidant support with glutathione and essential cofactors in a kid-approved, fruity lozenge that can be easily ...

    View full details
    Original price $50 - Original price $300
    Original price $50 - Original price $300
    Original price $150
    $150
    $50.00 - $255.00
    Save 67%
    $50.00 - $255.00
    $50.00 - $255.00
    Current price $50
  • Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!

    Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).

    Supplement bottle labeled 'Optimal PC' by Seeking Health on a white background

    Optimal PC

    4.9
    Rated 4.9 out of 5 stars
    181 Reviews
    SHOP NOW $47
    From $47

    Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...

    View full details
    Original price $47 - Original price $282
    Original price $47 - Original price $282
    Original price $141
    $141
    $47.00 - $239.70
    Save 67%
    $47.00 - $239.70
    $47.00 - $239.70
    Current price $47
  • Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.

    Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).

    Riboflavin Supplement Bottle

    Riboflavin

    4.9
    Rated 4.9 out of 5 stars
    123 Reviews
    SHOP NOW $25
    From $25

    Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...

    View full details
    Original price $25 - Original price $150
    Original price $25 - Original price $150
    Original price $75
    $75
    $25.00 - $127.50
    Save 67%
    $25.00 - $127.50
    $25.00 - $127.50
    Current price $25
  • A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.

    Orange Flavored Electrolytes Sticks
    Best Seller

    Optimal Electrolyte Sticks

    4.7
    Rated 4.7 out of 5 stars
    152 Reviews
    SHOP NOW $40
    From $40

    Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...

    View full details
    Original price $40 - Original price $240
    Original price $40 - Original price $240
    Original price $120
    $120
    $40.00 - $204.00
    Save 67%
    $40.00 - $204.00
    $40.00 - $204.00
    Current price $40
  • Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!

    PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.

    PQQ Lozenge by Seeking Health
    Best Seller

    PQQ Lozenge

    4.7
    Rated 4.7 out of 5 stars
    325 Reviews
    SHOP NOW $35
    From $35

    Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...

    View full details
    Original price $35 - Original price $210
    Original price $35 - Original price $210
    Original price $105
    $105
    $35.00 - $178.50
    Save 67%
    $35.00 - $178.50
    $35.00 - $178.50
    Current price $35
  • Keep your homocysteine levels in check with the unique formula found in Homocysteine Nutrients!

    Homocysteine Nutrients—Provides the 5 nutrients your body requires for optimal methylation, including folate, methylcobalamin, and adenosylcobalamin, to support normal homocysteine breakdown for heart health support.

    Supplement bottle labeled 'Homocysteine Nutrients' by Seeking Health on a white background
    Best Seller

    Homocysteine Nutrients

    4.9
    Rated 4.9 out of 5 stars
    281 Reviews
    SHOP NOW $37
    From $37

    Key Benefits and Actions† Supports healthy methylation and homocysteine levels Powerful heart health support Supports healthy cognition and brai...

    View full details
    Original price $37 - Original price $222
    Original price $37 - Original price $222
    Original price $111
    $111
    $37.00 - $188.70
    Save 67%
    $37.00 - $188.70
    $37.00 - $188.70
    Current price $37
  • Help your body metabolize homocysteine, normalize mood, balance hormones, and get restful sleep with P-5-P (Pyridoxal 5-Phosphate)!

    P-5-P (Pyridoxal 5-Phosphate)—Contains a potent 25 mg of vitamin B6 (1,471% Daily Value) in the active form of P-5-P (pyridoxal 5’-phosphate), ideal if you are deficient or require higher amounts.

    P-5-P (Pyridoxal 5-Phosphate)

    P-5-P (Pyridoxal 5-Phosphate)

    4.9
    Rated 4.9 out of 5 stars
    126 Reviews
    SHOP NOW $22
    From $22

    Key Benefits and Actions† Active, bioavailable form of vitamin B6 Homocysteine metabolism support Supports a healthy mood Who Needs P-5-P (Pyri...

    View full details
    Original price $22 - Original price $132
    Original price $22 - Original price $132
    Original price $66
    $66
    $22.00 - $112.20
    Save 67%
    $22.00 - $112.20
    $22.00 - $112.20
    Current price $22
  • Support healthy detoxification and immune system functioning with easy-to-swallow Glutathione with Cofactors!

    Glutathione with Cofactors—A unique formula with Emothion™ and S-Acetyl-L-Glutathione for lung, skin, eye, and immune system support, all in a small taste- and smell-free capsule!

    Supplement bottle labeled 'Glutathione with Cofactors' on a white background
    Best Seller

    Glutathione with Cofactors ( formerly Glutathione Plus)

    4.9
    Rated 4.9 out of 5 stars
    217 Reviews
    SHOP NOW $65
    From $65

    Supports your body's natural response to everyday chemical exposures—from formaldehyde in new furniture and gas stoves to chlorine in your water, ...

    View full details
    Original price $65 - Original price $390
    Original price $65 - Original price $390
    Original price $195
    $195
    $65.00 - $331.50
    Save 67%
    $65.00 - $331.50
    $65.00 - $331.50
    Current price $65
  • Dirty Genes: The Histamine Workbook

    Dirty Genes®: The Histamine Workbook

    4.7
    Rated 4.7 out of 5 stars
    35 Reviews
    SHOP NOW $8
    From $8

    Original price $8 - Original price $8
    Original price
    $8
    $8.00 - $8.00
    Current price $8
  • Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!

    Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.

    Optimal Electrolyte Strawberry Watermelon Container | Strawberry Watermelon / 1 Pack, Strawberry Watermelon / 3 Pack, Strawberry Watermelon / 6 Pack
    Best Seller
    HSA / FSA

    Optimal Electrolyte

    4.6
    Rated 4.6 out of 5 stars
    1,674 Reviews
    SHOP NOW $40
    From $40

    Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...

    View full details
    Original price $40 - Original price $240
    Original price $40 - Original price $240
    Original price $120
    $120
    $40.00 - $204.00
    Save 67%
    $40.00 - $204.00
    $40.00 - $204.00
    Current price $40
  • Support healthy methylation, MTHFR, and homocysteine levels with bioavailable L-Methylfolate!

    L-Methylfolate—A superior form of L-methylfolate that readily donates its methyl groups, aids the conversion of the amino acid homocysteine into methionine, and supports your entire methylation cycle.

    A bottle of Seeking Health L-Methylfolate capsules, which is a dietary supplement for methylation, mood, and cognitive support.

    L-Methylfolate

    4.8
    Rated 4.8 out of 5 stars
    113 Reviews
    SHOP NOW $20
    From $20

    Key Benefits and Actions† Powerful methylation, MTHFR, and homocysteine support Supports healthy cognition and mood Healthy genetic expression s...

    View full details
    Original price $20 - Original price $120
    Original price $20 - Original price $120
    Original price $60
    $60
    $20.00 - $102.00
    Save 67%
    $20.00 - $102.00
    $20.00 - $102.00
    Current price $20
  • Promote sustainable energy by supporting methylation, homocysteine, and MTHFR with Methyl B12 with L-Methylfolate!

    Methyl B12 with L-Methylfolate—Each serving contains a blend of bioavailable folate and vitamin B12 to support healthy methylation, homocysteine regulation, and energy production in a tasty, well-absorbed lozenge.

    Methyl B12 with L-Methylfolate
    Best Seller
    HSA / FSA

    Methyl B12 with L-Methylfolate

    4.9
    Rated 4.9 out of 5 stars
    885 Reviews
    SHOP NOW $27
    From $27

    A delicious, fast-absorbing lozenge that bypasses genetic bottlenecks to support healthy methylation, balanced homocysteine levels, mental clarity...

    View full details
    Original price $27 - Original price $162
    Original price $27 - Original price $162
    Original price $81
    $81
    $27.00 - $137.70
    Save 67%
    $27.00 - $137.70
    $27.00 - $137.70
    Current price $27
  • Gently support healthy blood iron levels with well-tolerated ingredients in Iron with Cofactors.

    Iron with Cofactors—provides a well-tolerated form of iron (ferric glycinate) along with targeted nutrients, including vitamins A, B12, and C, that help to absorb and utilize the iron.

    Supplement bottle labeled 'Iron with Cofactors' by Seeking Health on a white background

    Iron with Cofactors

    5.0
    Rated 5.0 out of 5 stars
    205 Reviews
    SHOP NOW $22
    From $22

    Key Benefits and Actions† Gentle iron complex supports optimal absorption Well-tolerated form of iron; Easy on the stomach Cofactor nutrients su...

    View full details
    Original price $22 - Original price $132
    Original price $22 - Original price $132
    Original price $66
    $66
    $22.00 - $112.20
    Save 67%
    $22.00 - $112.20
    $22.00 - $112.20
    Current price $22
  • Foster healthy energy production, mental clarity, and methylation with Hydroxo B12 with Folinic Acid!

    Hydroxo B12 with Folinic Acid—Provides a potent dose of methyl-free folate (folinic acid) and vitamin B12 (Hydroxo B12) in a delicious, well-digested lozenge.

    Hydroxo B12 with Folinic Acid | AB-1
    Best Seller

    Hydroxo B12 with Folinic Acid

    4.9
    Rated 4.9 out of 5 stars
    305 Reviews
    SHOP NOW $27
    From $27

    Key Benefits and Actions† Potent methyl-free B12 and folate Methylation, energy, and cognition support Supports healthy homocysteine levels and ...

    View full details
    Original price $27 - Original price $162
    Original price $27 - Original price $162
    Original price $81
    $81
    $27.00 - $137.70
    Save 67%
    $27.00 - $137.70
    $27.00 - $137.70
    Current price $27
  • Support the body’s normal antioxidant protection and healthy detoxification conveniently on the go with Glutathione with Cofactors Lozenges!

    Glutathione with Cofactors Lozenges—A great-tasting and effective glutathione lozenge with essential cofactors supporting the normal neutralization of toxic compounds that are generated by liver detoxification.

    Supplement bottle labeled 'Glutathione with Cofactors' by Seeking Health on a white background
    Best Seller
    HSA / FSA
    Essential for Spring

    Glutathione with Cofactors Lozenges ( formerly Glutathione Plus Lozenge )

    4.8
    Rated 4.8 out of 5 stars
    214 Reviews
    SHOP NOW $50
    From $50

    Delivers fast-acting, delicious antioxidant support with glutathione and essential cofactors in a kid-approved, fruity lozenge that can be easily ...

    View full details
    Original price $50 - Original price $300
    Original price $50 - Original price $300
    Original price $150
    $150
    $50.00 - $255.00
    Save 67%
    $50.00 - $255.00
    $50.00 - $255.00
    Current price $50
  • Conveniently support healthy choline levels for healthy cell walls, liver, and brain with Optimal PC!

    Optimal PC—Provides 800 mg of soy-free phospholipids from non-GMO sunflower lecithin in a unique phospholipid complex containing phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).

    Supplement bottle labeled 'Optimal PC' by Seeking Health on a white background

    Optimal PC

    4.9
    Rated 4.9 out of 5 stars
    181 Reviews
    SHOP NOW $47
    From $47

    Key Benefits and Actions† High-quality source of choline from phosphatidylcholine (PC) Supports healthy cell walls, liver, and brain Supports he...

    View full details
    Original price $47 - Original price $282
    Original price $47 - Original price $282
    Original price $141
    $141
    $47.00 - $239.70
    Save 67%
    $47.00 - $239.70
    $47.00 - $239.70
    Current price $47
  • Support MTHFR, MAOA, and GSR gene function for healthy homocysteine, neurotransmitter, antioxidant levels, and healthy methylation pathways with Riboflavin.

    Riboflavin—Contains a potent 400 mg of riboflavin per vegan-friendly capsule. Vitamin B2 is provided in the active and bioavailable form of riboflavin-5-phosphate (R-5-P).

    Riboflavin Supplement Bottle

    Riboflavin

    4.9
    Rated 4.9 out of 5 stars
    123 Reviews
    SHOP NOW $25
    From $25

    Key Benefits and Actions† Includes the biologically active form of riboflavin as R-5-P (Riboflavin 5’-Phosphate) Supports MTHFR, MAOA, and GSR g...

    View full details
    Original price $25 - Original price $150
    Original price $25 - Original price $150
    Original price $75
    $75
    $25.00 - $127.50
    Save 67%
    $25.00 - $127.50
    $25.00 - $127.50
    Current price $25
  • A convenient way to experience our electrolyte blend for healthy muscle contraction and relaxation and heart rhythm and contraction support. Each stick contains one serving of Optimal Electrolyte to mix with a glass of water.

    Orange Flavored Electrolytes Sticks
    Best Seller

    Optimal Electrolyte Sticks

    4.7
    Rated 4.7 out of 5 stars
    152 Reviews
    SHOP NOW $40
    From $40

    Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...

    View full details
    Original price $40 - Original price $240
    Original price $40 - Original price $240
    Original price $120
    $120
    $40.00 - $204.00
    Save 67%
    $40.00 - $204.00
    $40.00 - $204.00
    Current price $40
  • Support healthy energy production, oxidative stress, and aging responses with PQQ Lozenge!

    PQQ Lozenge—Contains 20 mg of Pyrroloquinoline Quinone Disodium Salt (PQQ), an antioxidant-like nutrient that supports healthy energy production and responses to oxidative stress.

    PQQ Lozenge by Seeking Health
    Best Seller

    PQQ Lozenge

    4.7
    Rated 4.7 out of 5 stars
    325 Reviews
    SHOP NOW $35
    From $35

    Key Benefits and Actions† Long lasting, antioxidant-like properties Supports mitochondrial development and growth Supports a healthy brain and h...

    View full details
    Original price $35 - Original price $210
    Original price $35 - Original price $210
    Original price $105
    $105
    $35.00 - $178.50
    Save 67%
    $35.00 - $178.50
    $35.00 - $178.50
    Current price $35
  • Keep your homocysteine levels in check with the unique formula found in Homocysteine Nutrients!

    Homocysteine Nutrients—Provides the 5 nutrients your body requires for optimal methylation, including folate, methylcobalamin, and adenosylcobalamin, to support normal homocysteine breakdown for heart health support.

    Supplement bottle labeled 'Homocysteine Nutrients' by Seeking Health on a white background
    Best Seller

    Homocysteine Nutrients

    4.9
    Rated 4.9 out of 5 stars
    281 Reviews
    SHOP NOW $37
    From $37

    Key Benefits and Actions† Supports healthy methylation and homocysteine levels Powerful heart health support Supports healthy cognition and brai...

    View full details
    Original price $37 - Original price $222
    Original price $37 - Original price $222
    Original price $111
    $111
    $37.00 - $188.70
    Save 67%
    $37.00 - $188.70
    $37.00 - $188.70
    Current price $37
  • Help your body metabolize homocysteine, normalize mood, balance hormones, and get restful sleep with P-5-P (Pyridoxal 5-Phosphate)!

    P-5-P (Pyridoxal 5-Phosphate)—Contains a potent 25 mg of vitamin B6 (1,471% Daily Value) in the active form of P-5-P (pyridoxal 5’-phosphate), ideal if you are deficient or require higher amounts.

    P-5-P (Pyridoxal 5-Phosphate)

    P-5-P (Pyridoxal 5-Phosphate)

    4.9
    Rated 4.9 out of 5 stars
    126 Reviews
    SHOP NOW $22
    From $22

    Key Benefits and Actions† Active, bioavailable form of vitamin B6 Homocysteine metabolism support Supports a healthy mood Who Needs P-5-P (Pyri...

    View full details
    Original price $22 - Original price $132
    Original price $22 - Original price $132
    Original price $66
    $66
    $22.00 - $112.20
    Save 67%
    $22.00 - $112.20
    $22.00 - $112.20
    Current price $22
  • Support healthy detoxification and immune system functioning with easy-to-swallow Glutathione with Cofactors!

    Glutathione with Cofactors—A unique formula with Emothion™ and S-Acetyl-L-Glutathione for lung, skin, eye, and immune system support, all in a small taste- and smell-free capsule!

    Supplement bottle labeled 'Glutathione with Cofactors' on a white background
    Best Seller

    Glutathione with Cofactors ( formerly Glutathione Plus)

    4.9
    Rated 4.9 out of 5 stars
    217 Reviews
    SHOP NOW $65
    From $65

    Supports your body's natural response to everyday chemical exposures—from formaldehyde in new furniture and gas stoves to chlorine in your water, ...

    View full details
    Original price $65 - Original price $390
    Original price $65 - Original price $390
    Original price $195
    $195
    $65.00 - $331.50
    Save 67%
    $65.00 - $331.50
    $65.00 - $331.50
    Current price $65
  • Dirty Genes: The Histamine Workbook

    Dirty Genes®: The Histamine Workbook

    4.7
    Rated 4.7 out of 5 stars
    35 Reviews
    SHOP NOW $8
    From $8

    Original price $8 - Original price $8
    Original price
    $8
    $8.00 - $8.00
    Current price $8
  • Quench your body’s thirst for healthy hydration with the unique blend of ingredients found in the improved formula of Optimal Electrolyte!

    Optimal Electrolyte—Formulated with key ingredients, including sodium from real Himalayan pink salt and potassium, PeakATP®, niacin, and magnesium that easily mixes with water to support hydration for heart and muscle health.

    Optimal Electrolyte Strawberry Watermelon Container | Strawberry Watermelon / 1 Pack, Strawberry Watermelon / 3 Pack, Strawberry Watermelon / 6 Pack
    Best Seller
    HSA / FSA

    Optimal Electrolyte

    4.6
    Rated 4.6 out of 5 stars
    1,674 Reviews
    SHOP NOW $40
    From $40

    Key Benefits:† Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with key ingredi...

    View full details
    Original price $40 - Original price $240
    Original price $40 - Original price $240
    Original price $120
    $120
    $40.00 - $204.00
    Save 67%
    $40.00 - $204.00
    $40.00 - $204.00
    Current price $40
  • Support healthy methylation, MTHFR, and homocysteine levels with bioavailable L-Methylfolate!

    L-Methylfolate—A superior form of L-methylfolate that readily donates its methyl groups, aids the conversion of the amino acid homocysteine into methionine, and supports your entire methylation cycle.

    A bottle of Seeking Health L-Methylfolate capsules, which is a dietary supplement for methylation, mood, and cognitive support.

    L-Methylfolate

    4.8
    Rated 4.8 out of 5 stars
    113 Reviews
    SHOP NOW $20
    From $20

    Key Benefits and Actions† Powerful methylation, MTHFR, and homocysteine support Supports healthy cognition and mood Healthy genetic expression s...

    View full details
    Original price $20 - Original price $120
    Original price $20 - Original price $120
    Original price $60
    $60
    $20.00 - $102.00
    Save 67%
    $20.00 - $102.00
    $20.00 - $102.00
    Current price $20

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