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Histamine Digest - Formerly Histamine Block

SALE $37.95

Quality DAO Supplement

  • Digests histamine fast using the patented DAOgest® enzyme
  • Eat and drink with confidence again!
  • Supports healthy histamine levels in the small intestines, colon, uterus, bladder, prostate and breast milk.

Who Needs Histamine Digest

Can’t digest histamine?

Histamine Digest can do it for you.

Now you can eat and drink with confidence.

Assess each statement below. If you relate any of them, then Histamine Digest may help you support healthy histamine levels:

  • After eating or drinking, I often feel worse but not sure why.
  • I have been told that I have a leaky gut. I want to support a healthy gut lining.
  • I’m breastfeeding and I notice my baby experiences colic when my diet consists of histamine containing foods or drinks.
  • I’m pregnant and experiencing morning sickness, nausea and vomiting of pregnancy.
  • I would love to support a healthy, comfortable menstrual cycle.
  • I noticed that when I was pregnant, my histamine intolerance was basically gone! Now that I’m not pregnant, my histamine symptoms are back again. So weird!
  • I need Metformin and want to support a healthy histamine response while taking it.
  • My bowel movements are often loose or just inconsistent
  • Certain probiotics make me feel worse - eg. Streptococcus, L. fermentum, L. casei, L. bulgaricus and I want to support healthy balance
  • My gut microbiome is messing with me. I’d like to support a healthy response to my gut microbiome.
  • I have a dirty DAO gene
  • SIBO is troubling me and I believe it’s contributing to my histamine intolerance. I’d like to support healthy histamine levels.
  • I want to enjoy eating and drinking a more varied menu again
  • I eat and drink lots of cured, aged, and fermented products
  • I experience uncomfortable symptoms after having the following foods or drinks (note: you are not allergic to these foods, they just make you feel off):
    • Alcohol, especially red wine or champagne
    • Aged cheeses (eg. Parmesan, Gouda, Swiss, Cheddar)
    • Aged meats (eg. salami, pepperoni, canned meat, sausages, jerky)
    • Fish
    • Tomatoes
    • Sausages
    • Orange juice
    • Pineapple juice
    • Very ripe fruit (eg. strawberries, bananas)
    • Avocados
    • Sauerkraut, Kimchi
    • Balsamic vinegar
    • Kombucha
    • Leftovers
  • I experience a few of the following symptoms after having high histamine foods or drinks
    • Headaches
    • Hives
    • Frequent inappropriate fatigue
    • Difficulty falling asleep
    • Loose stools
    • Bloating, gas
    • Stomach discomfort
    • Bladder discomfort
    • Nausea or pukey
    • Frequent peeing.
    • Waking up to pee at night
    • Ringing in the ears or fluid
    • Bedwetting
    • Heart palpitations or faster heart beat
    • Rashes, itchy skin or eczema
    • Sweating, flushing, red spots on skin or just feel hotter
    • Sneezing or runny nose
    • Irritability
    • Anxiousness
    • Nose bleeds

If a number of those resonated with you, then Histamine Digest is something that you should seriously consider.

If none of the statements above resonated with you, then Histamine Digest is not something you need currently.

Alternatively, consider Histamine Nutrients or ProBiota HistaminX.

Customer Review

Amazing Products

This product has been a game changer for us. My daughter can enjoy food so much more and road trips are no longer nearly as stressful. We take the Histamine Digest everywhere! ~ Esquibel F.

Key Ingredients In Histamine Digest

  • DAOgest® (Diamine oxidase): This patented enzyme, derived from porcine (pork) kidney extract, supports the healthy breakdown of histamine in many areas of your body - especially the small intestine, colon, placenta, kidney, appendix, testis and prostate.

Why Histamine Digest Works

You have a gene called DAO. This gene makes an enzyme that digests histamine.

Your DAO enzyme is found in various parts of your body in order to maintain healthy levels of histamine.

The problem is many people, and possibly you, do not have a DAO enzyme working very well for a variety of reasons.

This is why you may need Histamine Digest.

Histamine Digest provides you with the patented, lab tested and pure DAO enzyme called DAOgest®.

After you take a small capsule of Histamine Digest, the capsule breaks open and releases its contents of the DAO enzyme in your small intestine. The released DAO enzyme immediately starts digesting histamine for you so your body doesn’t have to.

Histamine Digest works on digesting histamine from these main sources of histamine:

  1. Food and drink
  2. Your gut’s immune system
  3. Your microbiome

By using Histamine Digest, you’ll once again support healthy levels of the DAO enzyme. By doing so, you may notice fewer symptoms of histamine intolerance!

Histamine Digest
Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 30 / 90

DAOgest® porcine kidney extract (Diamine Oxidase Activity 10,000 HDU)4.2 mg**
**Daily Value (DV) not established.

Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose, water, and gellan gum), and ascorbyl palmitate.
DAOgest®️ is a trademark l licensed by BIOIBERICA, S.A.U

    NOT Suitable for Vegetarians or Vegans
  • Delivery Method: Capsules
  • How To Store: Keep tightly closed in a cool, dry place out of reach by children.

Free Of: Dairy, Eggs, Fish, Gluten, GMO, Peanuts, Sesame, Shellfish, Soy, Tree Nuts, Wheat, Artificial Colors, and Artificial Flavors

How to Use Histamine Digest

When taken with meals, Histamine Digest helps break down histamine found in foods and drinks. Histamine will be at a healthy level which helps eliminate feelings related to histamine intolerance.†‡

When taken on an empty stomach, Histamine Digest helps break down histamine produced from the microbiome or your gut’s immune system.

This is a great idea to try: Take 1 capsule of Histamine Digest on an empty stomach to see if you feel better within 30 minutes.

Why would this be useful? High amounts of histamine are produced by an unhealthy microbiome, or an overactive gut immune system.

If you feel better, continue using Histamine Digest on an empty stomach as needed. Histamine Digest supports a healthy balance of histamine in the gut.

Histamine Digest may support healthy levels of histamine within the small intestine, colon, kidneys, uterus, appendix, placenta, prostate, or testicles. This is very important as unhealthy levels of histamine within these areas contribute to problems locally or throughout the body.

Children 4 years of age and older may use Histamine Digest. You may need to open the small capsule and mix in a bite of applesauce if they cannot swallow the small capsule.

Breastfeeding women may use Histamine Digest. Histamine gets absorbed from the gut and into breastmilk. If breastmilk has higher levels of histamine, the breastfeeding baby may experience colic. Infant colic is associated with higher levels of histamine. Support healthy levels of histamine in your breastmilk by taking Histamine Digest.

Pregnant women may use Histamine Digest if approved by their healthcare professional. Occasional nausea and vomiting of pregnancy is associated with high levels of histamine. Levels of histamine in a healthy pregnancy decrease below values found in healthy non-pregnant women. This is because the placenta is designed to produce a lot of the DAO enzyme. However, sometimes the levels of histamine exceed the ability of the placenta’s DAO enzyme to digest histamine.

In some complications of pregnancy, maternal blood histamine levels rise above those associated with a healthy pregnancy. Many of the complications of pregnancy, including preeclampsia, preterm labour, spontaneous abortion and hyperemesis gravidarum, are associated with increased levels of maternal blood histamine. Supporting healthy levels of maternal blood histamine levels during pregnancy, especially during such complications, may be helpful.

Suggested Use

As needed, anytime, take 1 capsule before eating or drinking. Alternatively, as needed, take 1 capsule away from food or drink if wanting to support uterine comfort during the menstrual cycle, occasional nausea from pregnancy or healthy histamine levels in your digestive system. Capsules may be opened and sprinkled on a bite of food. Use as directed by your healthcare professional.

Do not take Histamine Digest and knowingly eat foods you are allergic to—it will not prevent allergic reactions.


Consult with your healthcare practitioner prior to use. Do not use if inner tamper seal is damaged.

NOT Suitable for

Vegetarians or Vegans

Delivery Method


How to Store

Keep closed in a cool, dry place out of reach by children.

FAQs for Histamine Digest

What is the purpose of each ingredient in Histamine Digest?

Ingredients Purpose
DAOgest® (diamine oxidase) The enzyme that breaks down histamine in various parts of the body - especially the small intestine, colon, placenta, kidney, appendix, testis and prostate.

Why is Histamine Digest not suitable for vegans or vegetarians?

Histamine Digest is not vegetarian or vegan because the DAO (diamine oxidase) is from porcine (pig) sources.

Which histamine product is right for me?

Check out this Histamine Supplement Comparison Chart.

If you have a question that's not addressed
here, see all frequently asked questions.


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What our customers say

Real reviews from real customers.

Rated 4.8 out of 5 stars
Based on 758 reviews
Total 5 star reviews: 658 Total 4 star reviews: 66 Total 3 star reviews: 15 Total 2 star reviews: 6 Total 1 star reviews: 13
93%would recommend these products
758 reviews
  • P
    Verified Buyer
    Histamine Digest - Formerly Histamine Block
    Histamine Digest - Formerly Histamine Block
    I recommend this product
    Rated 5 out of 5 stars
    5 days ago
    Lifesaver for histamine sensitivity

    This is a great product and I wish I had found it sooner. I have histamine sensitivities and so every meal I eat is a risk of a histamine response. Taking this with each meal has given me peace of mind until I can get my gut issues in order.

  • SS
    Safari S.
    Verified Buyer
    Histamine Digest - Formerly Histamine Block
    Histamine Digest - Formerly Histamine Block
    I recommend this product
    Rated 5 out of 5 stars
    6 days ago
    Love This!

    Great product! Works well. Tried cheaper ones, which didn't work or caused more allergies!

  • JT Profile picture for Jennifer logo
    Jennifer T.
    Verified Buyer
    Histamine Digest - Formerly Histamine Block
    Histamine Digest - Formerly Histamine Block
    I recommend this product
    Rated 4 out of 5 stars
    6 days ago

    I am struggling with MCAS & these are helpful when I know I'm having something that is a trigger for me. Though I do find one isn't usually enough to do the job.

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